There are currently 48 active clinical trials seeking participants for Autism research studies. The states with the highest number of trials for Autism participants are California, Florida, Ohio and New York.
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01778504
Recruiting
Background: - Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood. Researchers want to look at people of all ages who have these disorders that started in childhood. They will also look at relatives of people with these disorders. This information will allow doctors to learn more about childhood behavioral problems and how they are inherited. It may also help doct... Read More
Gender:
ALL
Ages:
99 years and below
Trial Updated:
04/23/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurological Disorder, Autism, Sleep
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Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
NCT03434080
Recruiting
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This ma... Read More
Gender:
ALL
Ages:
Between 3 months and 5 years
Trial Updated:
04/23/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Autism, Cerebral Palsy
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Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
NCT06859918
Recruiting
The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings. The Investigators will... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Autism Spectrum Disorder, Autism, Autistic Disorder, Asperger Syndrome
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The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
NCT00271622
Recruiting
The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific protocols at NIH.
Gender:
ALL
Ages:
6 weeks and above
Trial Updated:
04/22/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurologic Disorders, Autism, Neurodegenerative Disease, Neurobehavioral Manifestation
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Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers
NCT05880225
Recruiting
The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and social communication skills, or a music-enhanced version of RIT. Throughout their participation in the intervention, toddlers will complete study procedures of viewing naturalistic videos of infant-dire... Read More
Gender:
ALL
Ages:
Between 18 months and 36 months
Trial Updated:
04/22/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Autism, Autism Spectrum Disorder
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Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
NCT05741840
Recruiting
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
03/27/2025
Locations: UC San Diego Center for Healthy Eating and Activity Research (CHEAR), La Jolla, California
Conditions: Autism Spectrum Disorder, Obesity, Childhood, Autism
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Biomarkers Research in Anxiety for Validation and Efficacy
NCT06221176
Recruiting
A within-subjects design will be used for this preliminary investigation of four biomarkers across two contexts of use: prediction of treatment response (i.e., stratification) and quantification of response (i.e., change).
Gender:
ALL
Ages:
Between 3 years and 6 years
Trial Updated:
03/10/2025
Locations: Boston Children's Hospital, Two Brookline Place, Brookline, Massachusetts
Conditions: Autism, Autism Spectrum Disorder
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A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum
NCT06255925
Recruiting
The investigators are looking to evaluate how effective a training program that focuses on character strengths may be in improving job maintenance skills in young adults. The investigators are examining the effects of this intervention in young adults who feel they would like to help in improving their satisfaction with work, and in keeping their jobs.
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
03/06/2025
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Autism
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Use of Eye Tracking to Aid in Autism Risk Detection
NCT06471504
Recruiting
The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.
Gender:
ALL
Ages:
Between 12 months and 48 months
Trial Updated:
03/04/2025
Locations: Riley Hospital for Children, Indianapolis, Indiana
Conditions: Autism
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Trial of Diphenhydramine for Sleep in Children With Autism
NCT05501678
Recruiting
The purpose of this study is to examine the effect of diphenhydramine on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Diphenhydramine is an anti-histaminergic agent with strong hypnotic properties. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of diphenhydramine on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
02/28/2025
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
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Pilot Trial of Pregnenolone in Autism
NCT02627508
Recruiting
This is a research study to examine the tolerability and effectiveness of pregnenolone in individuals with autism. Pregnenolone is a naturally occurring steroid hormone in the brain that has been implicated in treating various psychiatric conditions. The investigators hope to learn the effects and safety of using pregnenolone in reducing irritability and sensitivity to sensory differences and improving social communication in individuals with autism. The investigators hope by studying the effect... Read More
Gender:
ALL
Ages:
Between 14 years and 25 years
Trial Updated:
02/28/2025
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
Register for Updates
Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
NCT06472115
Recruiting
This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism and investigate 1) whether caregivers can learn to deliver the adapted Supportive Parenting for Anxious Childhood emotions (SPACE) intervention for IS via telehealth and 2) whether children will show greater improvement in IS behaviors.
Gender:
ALL
Ages:
Between 6 years and 11 years
Trial Updated:
02/21/2025
Locations: Jennifer Phillips, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
Register for Updates