There are currently 183 active clinical trials seeking participants for Heart Failure research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Pennsylvania.
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197
Recruiting
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Aurora, CO Investigative Site, Aurora, Colorado +3 locations
Conditions: Heart Failure, Acute Heart Failure
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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
NCT03142152
Recruiting
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona +61 locations
Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
NCT05753059
Recruiting
Randomized placebo-controlled, double-blind, double-dummy, crossover design testing combinations placebo/placebo, bendroflumethiazide/placebo, amiloride/placebo, and bendroflumethiazide/amiloride added to bumetanide.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure
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Project 2: ACHIEVE- HF
NCT05330221
Recruiting
This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health Inequities by Early PreVEntion in the GREAT LakEs Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Wayne State University, Detroit, Michigan
Conditions: Heart Failure, Hypertension
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The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients
NCT05858320
Recruiting
The SmartHF study is a 12-week prospective randomized controlled multicenter clinical trial. This study will investigate the efficacy of an adaptive web application to facilitate guideline-directed medical therapy (GDMT) optimization in HFrEF patients. Eligible participants will be randomized to the web application intervention or control in a 1:1 manner, stratified by site. The intervention is an adaptive medication optimization web application that extracts and analyzes the EHR data with a co... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Emory University, Grady Hospital, Atlanta, Georgia +3 locations
Conditions: Heart Failure
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Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure ( BETA )
NCT06045117
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CardioPumonary Management (CPM) system reduces the rate of heart failure (HF) related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system against those who are not. This can either be done using institutions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Cone Health, Greensboro, North Carolina
Conditions: Heart Failure
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Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)
NCT06052072
Recruiting
This early feasibility study is intended to characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Group 2 Pulmonary Hypertension
Gender:
All
Ages:
Between 22 years and 85 years
Trial Updated:
02/22/2024
Locations: Duke University, Durham, North Carolina
Conditions: Group 2 Pulmonary Hypertension, Heart Failure
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Feasibility and Efficacy Study of the CardioPulmonary Monitoring (CPM) System in Patients With Chronic Heart Failure
NCT05978518
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CPM system reduces the rate of HF related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system & have their data reviewed by a physician against those who are using the CPM system and not having their data rev... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Prisma Health, Greenville, South Carolina
Conditions: Heart Failure
Register for Updates
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
NCT05650541
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CPM system reduces the rate of HF related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system against those who are not. This can either be done using institutions averages, if available, or through a control... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Desert Oasis Healthcare, Palm Springs, California +3 locations
Conditions: Heart Failure
Register for Updates
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure (BETA)
NCT06078280
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CardioPumonary Management (CPM) system reduces the rate of heart failure (HF) related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system against those who are not. This can either be done using institutions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Desert Oasis Healthcare, Palm Springs, California
Conditions: Heart Failure
Register for Updates
Clinical Data Collection Study Using CPM System
NCT06007079
Recruiting
This study will assess the deployment of the ADI CPM System in a home setting and determine the interoperability of the CPM System within existing care pathways for HF patients. Clinicians will be blinded to CPM generated data and acquired physiologic data will not be used in clinical decision-making. After conclusion of this phase, a retrospective review of CPM System-acquired data will be compared with changes in treatment and HF events. This retrospective review will inform the subsequent des... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Heart Failure
Register for Updates
Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
NCT06253104
Recruiting
This study aims to determine, via skeletal muscle ultrasound (US), the extent, timing and relationship between skeletal muscle mass loss and outcomes after orthotropic heart transplantation (OHT) and left ventricular assist device (LVAD) implantation amongst patients with cardiogenic shock. Advanced therapies such as OHT and VADs in the heart failure (HF) population may promote skeletal muscle mass and subsequent quality of life, but there is a lack of literature assessing muscle mass changes in... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
02/22/2024
Locations: Tufts Medical Center, Boston, Massachusetts
Conditions: Heart Failure, Muscle Atrophy, Skeletal Muscle Atrophy, Cardiogenic Shock
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