Migraine Clinical Trials

A listing of 49 Migraine clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 49 active clinical trials seeking participants for Migraine research studies. The states with the highest number of trials for Migraine participants are Florida, California, Texas and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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Cooling to Alleviate Migraine #3

NCT06874361

Recruiting

This is a prospective, double-blind, sham-controlled, randomized, decentralized trial. This study aims to assess the safety and efficacy of the Mi-Helper transnasal cooling device for acute treatment of migraine in an at home setting. Adults aged 18 years to 70 years old with a diagnosis of migraine (with or without aura) for at least one year will be recruited for this study.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

08/13/2025

Locations: SPRIM Pro, Indian Harbour Beach, Florida

Conditions: Migraine With or Without Aura, Migraine, Migraine Headache

Learn More ›

A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments

NCT06323928

Recruiting

The purpose of this trial is to determine which doses of Lu AG09222 are recommended to help prevent migraines. People who join this trial have already tried 1 to 4 other available medications to prevent their migraines, but these medications have not helped them.

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

08/13/2025

Locations: Accel Research Sites Network - Neurology and Neurodiagnostic of Alabama, Hoover, Alabama +115 locations

Accel Research Sites Network - Neurology and Neurodiagnostic of Alabama, Hoover, Alabama

Profound Research - Neurology Center of Southern California, Carlsbad, California

Neurology Center of North Orange County, Fullerton, California

CenExel CNS, Los Alamitos, California

ASCLEPES Research Centers, Sherman Oaks, California

Ki Health Partners LLC DBA New England Institute for Clinical Research, Stamford, Connecticut

K2 Medical Research - Winter Garden, Clermont, Florida

Clinical Neuroscience Solutions, Inc., Jacksonville, Florida

K2 Medical Research, LLC, Maitland, Florida

Aqualane Clinical Research, Naples, Florida

K2 Medical Research Tampa LLC, Tampa, Florida

Premiere Research Institute Palm Beach, West Palm Beach, Florida

Accellacare and McFarland Clinic, Ames, Iowa

Clinical Research Professionals, Chesterfield, Missouri

Healthcare Research Network, Hazelwood, Missouri

Dent Neurosciences Research Center, Inc., Amherst, New York

North Suffolk Neurology, PC., Port Jefferson Station, New York

Accellacare of Cary - Cary Medical Group, Cary, North Carolina

Headache Wellness Center, Greensboro, North Carolina

Raleigh Medical Group, Raleigh, North Carolina

M3 Wake Research, Inc, Raleigh, North Carolina

Accellacare of Rocky Mount, Rocky Mount, North Carolina

Triad Neurological Associates, Winston-Salem, North Carolina

Accellacare of Charleston, Mount Pleasant, South Carolina

Internal Medicine and Pediatric Associates of Bristol, PC, Bristol, Tennessee

Cedar Health Research, LLC, Dallas, Texas

Mercury Clinical Research, Sugar Land, Texas

MedStar Health - Neurology Clinic at McLean, McLean, Virginia

Diagnostic Consultative Center Convex Ltd, Sofia, Sofiiska

MC Nevrocentrum, Plovdiv, Not set

MC Rusemed-OOD, Ruse, Not set

Neurosanatio s.r.o., Litomyshl, Pardubicky

Dr. Radomir Talab MD, Office of, Hradec Kralove, Not set

Neuros s.r.o, Plzen, Not set

Clintrial s. r. o., Prague, Not set

DADO MEDICAL s.r.o., Praha 2, Not set

Praglandia s.r.o, Praha 5, Not set

Axon Clinical s r.o, Praha 5, Not set

Neurologicka ordinace FORBELI sro, Praha 6, Not set

Institut neuropsychiatricke pece, Praha 8, Not set

Neurologicka ambulance, Slezska Ostrava, Not set

NeuroMed Zlin s.r.o., Zlin, Not set

Glostrup Hospital, Glostrup, Not set

Bispebjerg Hospital - Region Capital, Kobenhavn, Not set

Centre Hospitalier Universitaire de Lyon, Hopital Pierre Wertheimer, Bron, Not set

Centre Hospitalier Regional Universitaire de Lille - Hopital Roger Salengro, Lille, Not set

Assistance Publique Hopitaux de Marseille (AP-HM) - Hopital de La Timone, Marseille Cedex 5, Not set

Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital Pierre-Paul Riquet, Toulouse, Not set

Malkhaz Katsiashvili Multiprofile Emergency Medicine Center, Tbilisi, Not set

American Hospital Network, Tbilisi, Not set

Archangel St Michael Multiprofile Clinical Hospital, Tbilisi, Not set

Jo Ann Medical Center, Tbilisi, Not set

JSC K. Eristavi National Center of Experimental and Clinical Surgery, Tbilisi, Not set

Aversi Clinic, Tbilisi, Not set

MD Georgia Staff Physician MediClub Georgia, Tbilisi, Not set

S. Khechinashvili University Hospital, Tbilisi, Not set

Charite - Universitaetsmedizin Berlin - Campus Charite Mitte (CCM), Berlin, Not set

Studienzentrum Dr. Bischof GmbH, Boeblingen, Not set

Headache Center Frankfurt, Frankfurt, Not set

Klinik Haag i. OB, Haag in Oberbayern, Not set

Siteworks - Hannover, Hannover, Not set

Siteworks - Heidelberg, Heidelberg, Not set

S-Medicon Kft., Budapest, Central Hungary (Közép-Magyarország)

Komarom-Esztergom Varmegyei Szent Borbala Korhaz, Tatabanya, Not set

Jinnouchi Neurosurgery Clinic, Kasuga-shi, Fukuoka-Ken

Ikeda Neurosurgery Clinic, Kasuga-shi, Fukuoka-Ken

Nakamura Memorial Hospital, Sapporo, Hokkaid¿

Mito Kyodo General Hospital, Mito, Ibaraki

Iwate Medical University Uchimaru Medical Center, Morioka, Iwate

Atsuchi Neurosurgical Hospital, Kagoshima-shi, Kagoshima-Ken

Tanaka Neurosurgery & Headache Clinic, Kagoshima-city, Kagoshima

Shonan Keiiku Hospital, Fujisawa-shi, Kanagawa-ken

Sendai Headache and Neurology Clinic Medical Corporation, Sendai-shi, Miyagi-Ken

Tominaga Hospital, Osaka-shi, Osaka-Fu

Saitama Medical University Hospital, Iruma-gun, Saitama

Japanese Red Cross Shizuoka Hospital, Shizuoka-shi, Shizuoka-Ken

Dokkyo Medical University Hospital, Shimotsuga-Gun, Tochigi

Shinagawa Strings Clinic, Minato-ku, Tokyo

Kitasato University Kitasato Institute Hospital, Minato-ku, Tokyo

Keio University Hospital, Tokyo, Not set

Hospital of Lithuanian University of Health Sciences Kaunas, Kaunas, Not set

PI University Hospital of Klaipeda, Klaipeda, Not set

Medicum Centrum, Taurage, Not set

Centrum Medyczne Neuroprotect, Warszawa, Mazowieckie

Landa Specjalistyczne Gabinety Lekarskie, Krakow, Małopolskie

Neuro-Care sp. z o.o. sp. Komandytowa, Katowice, Slaskie

Centrum Medyczne HCP sp. z o.o, Poznan, Wielkopolskie

Centrum Medczyne Pratia Bydgoszcz, Bydgoszcz, Not set

Centrum Kliniczno-Badawcze J.Brzezicki, B.Gornikiewicz-Brzezicka Lekarze Spolka partnerska, Elblag, Not set

Pratia MCM Krakow, Krakow, Not set

Centrum Opieki Zdrowotnej OrkanMed, Ksawerow, Not set

Appletreeclinics Network Sp. z o.o., Lodz, Not set

Clinirem Sp. z o.o., Lublin, Not set

Indywidualna Praktyka Lekarska Dr hab. n. med. Anna Szczepanska-Szerej, Lublin, Not set

Centrum Medyczne Hope Clinic Sebastian Szklener, Lublin, Not set

Twoja Przychodnia NCM, Nowa Sol, Not set

Instytut Zdrowia dr Boczarska-Jedynak, Oswiecim, Not set

Neurologiczny Niepubliczny ZOZ Centrum Leczenia SM Osrodek Badan Klinicznych im. dr n. med. Hanki..., Plewiska, Not set

RCMed Oddzial Sochaczew, Sochaczew, Not set

MTZ Clinical Research Powered by Pratia, Warszawa, Not set

MIGRE Polskie Centrum Leczenia Migreny, Wroclaw, Not set

ClinHouse Centrum Medyczne, Zabrze, Not set

Sc Clubul Sanatatii S.R.L., Campulung,, Judet Arges

Policlinica CCBR S.R.L., Bucuresti, Not set

The Emergency County Clinical Hospital St. Andrew Constanta, Constanta, Not set

Private Practice - Dr. Beáta Dupejová, Banska Bystrica, Not set

IN MEDIC s.r.o, Bardejov, Not set

KONZILIUM s.r.o., Dubnica nad Vahom, Not set

SANERA, s.r.o., Presov, Not set

Hospital General Universitario de Alicante, Alicante, Not set

Parc de Salut Mar - Hospital del Mar, Barcelona, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Clinica Universidad de Navarra, Madrid, Not set

Clinica Universidad de Navarra, Pamplona, Not set

Hospital Clinico Universitario de Valencia (Instituto de Investigacion Sanitaria INCLIVA), Valencia, Not set

Hospital Universitario La Fe de Valencia, Valencia, Not set

Conditions: Migraine

Learn More ›

Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

NCT06543914

Recruiting

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate the effectiveness of atogepant in treating adult participants with migraine in a real-world setting. Atogepant is an approved drug for preventive treatment of migraine in adults. Approximately 1000 adult participants who are prescribed atogepant by their doctors will be enrolled in this study across the world. Partici... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Neurology and Neurodiagnostics of Alabama /ID# 267614, Hoover, Alabama +79 locations

Neurology and Neurodiagnostics of Alabama /ID# 267614, Hoover, Alabama

Barrow Neurological Institute - Dignity Health St. Joseph's Hosp and Medical Ctr /ID# 267610, Phoenix, Arizona

Kenneth Martinez MD, A Medical Corp /ID# 267834, Aliso Viejo, California

Los Angeles Headache Center /ID# 267570, Los Angeles, California

Alcanza Clinical Research, LLC /ID# 267838, Lake Mary, Florida

Norton Cancer Institute - St. Matthews /ID# 267605, Louisville, Kentucky

Dent Neurologic Institute - Amherst /ID# 267606, Amherst, New York

Grace Forde /ID# 267596, N. New Hyde Park, New York

Thomas Jefferson University Hospital /ID# 267572, Philadelphia, Pennsylvania

Inova Health Care System /ID# 267615, Falls Church, Virginia

Neuroscience Group /ID# 267571, Neenah, Wisconsin

Cliniques Universitaires UCL Saint-Luc /ID# 270545, Bruxelles, Bruxelles-Capitale

Universitair Ziekenhuis Brussel /ID# 269799, Jette, Bruxelles-Capitale

Chu Tivoli /ID# 271254, La Louvière, Hainaut

Centre Hospitalier Régional de la Citadelle /ID# 270539, Liège, Liege

Groupe Sante CHC - Clinique du MontLegia /ID# 270218, Liège, Liege

OLV Ziekenhuis Aalst /ID# 270284, Aalst, Oost-Vlaanderen

AZ Sint-Jan Brugge /ID# 270540, Brugge, West-Vlaanderen

AZ Groeninge /ID# 272772, Kortrijk, West-Vlaanderen

Calgary Headache Assessment and Management Program /ID# 270266, Calgary, Alberta

Burrard Health Center /ID# 270268, Vancouver, British Columbia

Dr. Renju Kuriakose Prof. Corp. /ID# 273178, Saint John, New Brunswick

Maritime Neurology /ID# 270270, Halifax, Nova Scotia

Centricity /ID# 271478, London, Ontario

Bayshore Neurology /ID# 270673, Ottawa, Ontario

Sunnybrook Health Sciences Centre /ID# 273207, Toronto, Ontario

Centre de Recherche St-Louis /ID# 270957, Lévis, Quebec

Genge Partners /ID# 270267, Montreal, Quebec

Universitaetsklinikum Heidelberg /ID# 278134, Heidelberg, Baden-Wuerttemberg

Praxis fur Neurologie Dr. med. Martin Delf /ID# 275918, Hoppegarten, Brandenburg

Zentrum Für Klinische Forschung Dr. Irma Schöll /ID# 275642, Bad Homburg, Hessen

Universitaetsmedizin Greifswald /ID# 276678, Greifswald, Mecklenburg-Vorpommern

ZNS Siegen /ID# 275660, Siegen, Nordrhein-Westfalen

Schmerzklinik Kiel /ID# 275592, Kiel, Schleswig-Holstein

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 275760, Berlin, Not set

Schmerzzentrum Berlin /ID# 275819, Berlin, Not set

Neurologischen Facharztzentrum Berlin /ID# 275919, Berlin, Not set

Städtisches Klinikum Brandenburg /ID# 275725, Brandenburg, Not set

IRCCS Ospedale San Raffaele /ID# 273153, Milan, Milano

Sapienza University of Rome /ID# 273506, Rome, Roma

Azienda Ospedaliero Universitaria delle Marche /ID# 273349, Ancona, Not set

Fondazione Mondino Istituto Neurologico Nazionale a Carattere Scientifico IRCCS /ID# 273155, Pavia, Not set

Gelre Ziekenhuis /ID# 272429, Apeldoorn, Gelderland

Zaans Medisch Centrum /ID# 269603, Zaandam, Noord-Holland

Isala, locatie Zwolle /ID# 269602, Zwolle, Overijssel

Maasstad Ziekenhuis /ID# 269601, Rotterdam, Zuid-Holland

Hodeverket /ID# 271383, Sandnes, Rogaland

Oslo Hodepinesenter AS /ID# 271384, Oslo, Not set

Hospital da Luz /ID# 267002, Lisbon, Lisboa

CUF Sintra Hospital /ID# 272394, Sintra, Lisboa

Campus Neurológico Sénior /ID# 272392, Torres Vedras, Lisboa

Hospital CUF Porto /ID# 272788, Porto, Not set

Hospital Regional Universitario de Malaga /ID# 268272, Malaga, Andalucia

Hospital Universitario Severo Ochoa /ID# 268249, Leganés, Madrid

Hospital Universitario Puerta de Hierro - Majadahonda /ID# 268246, Majadahonda, Madrid

Hospital Universitario Virgen Macarena /ID# 268244, Seville, Sevilla

Hospital Universitario Vall d'Hebron /ID# 268222, Barcelona, Not set

Hospital Universitario de La Princesa /ID# 268245, Madrid, Not set

Hospital Universitario La Paz /ID# 268238, Madrid, Not set

Hospital Universitario Virgen del Rocio /ID# 268223, Sevilla, Not set

Hospital Clinico Universitario de Valladolid /ID# 268225, Valladolid, Not set

Hospital Clinico Universitario Lozano Blesa /ID# 268243, Zaragoza, Not set

Karolinska Universitetssjukhuset - Huddinge /ID# 265295, Huddinge, Stockholms Lan

Neurology Clinic /ID# 266707, Stockholm, Stockholms Lan

Skaneuro /ID# 265203, Lund, Not set

ZURZACH Care /ID# 265697, Bad Zurzach, Aargau

NeuroPraxis Birseck /ID# 266140, Reinach BL, Basel-Landschaft

DYA Swiss Institut SA /ID# 266891, Lugano, Ticino

EOC Ospedale Regionale Lugano /ID# 266887, Lugano, Ticino

CHUV, Centre hospitalier universitaire vaudois /ID# 266551, Lausanne, Vaud

Kopfwehzentrum Hirslanden Zuerich /ID# 265817, Zollikon, Zuerich

Inselspital, Universitaetsspital Bern /ID# 265818, Bern, Not set

Tri-Service General Hospital /ID# 272082, Taipei, Not set

Linkou Chang Gung Memorial Hospital /ID# 272084, Taoyuan City, Not set

Hull Royal Infirmary /ID# 276819, Hull, East Riding Of Yorkshire

Western General Hospital - NHS Lothian /ID# 277029, Edinburgh, Edinburgh, City Of

Cripps Health Centre /ID# 277474, Nottingham, Nottinghamshire

Great Western Hospital /ID# 276693, Swindon, Wiltshire

Worcestershire Royal Hospital /ID# 276902, Worcester, Worcestershire

Ulster Hospital - South Eastern Health & Social Care Trust /ID# 276900, Belfast, Not set

Conditions: Migraine

Learn More ›

Migraine in Adolescents

NCT05654012

Recruiting

Aim 1. To identify psychophysical and neural factors predicting migraine onset in adolescents Aim 2a. To determine hormonal, psychophysical, and neural changes associated with migraine onset. Aim 2b. To identify the temporal relationships between hormonal, psychophysical, and neural changes preceding vs. following migraine onset. Aim 3. To identify psychophysical and neural factors predicting migraine prognosis in adolescents with migraine.

Gender:

ALL

Ages:

Between 10 years and 13 years

Trial Updated:

08/12/2025

Locations: Washington University School of Medicine, Saint Louis, Missouri

Conditions: Migraine

Learn More ›

Endometriosis and Migraine

NCT06785129

Recruiting

This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.

Gender:

FEMALE

Ages:

Between 12 years and 45 years

Trial Updated:

08/11/2025

Locations: Washington University School of Medicine, Saint Louis, Missouri

Conditions: Migraine, Endometriosis

Learn More ›

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

NCT05125302

Recruiting

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children. The purpose of this study is to evaluate how safe and effective ubrogepant is in the acute treatment of migraine in children and adolescents. Ubrogepant is a drug approved for the acute treatment of migraine in adults. Children and adolescents (aged 6-17 years) with a history of migraine will be enrolled. The study will include 2 cohorts of participants - PK Cohort and Main Study (non-PK cohort). Participants aged 6-11 years in the PK Cohort will receive Dose A or Dose B of Ubrogepant for PK analysis to determine dose selection for the main study. In the main study, after dose selection, children aged 6-11 years will be randomized to receive either low or high dose of Ubrogepant or placebo. There is a 1 in 3 chance that a participant will be assigned to placebo. Adolescents aged 12-17 years will be randomized to receive either low or high dose of Ubrogepant or placebo with a 1 in 3 chance of placebo assignment. For qualifying migraine attacks, participants will receive oral tablets of the double-blind study intervention. There will be an option to take a second dose of double-blind study intervention (identical to initial dose), or rescue medication, at least 2 hours after the initial dose, for headache of moderate/severe intensity. Around 1059 participants will be enrolled in the study in approximately 120 sites in the United States. The study duration will be up to 6 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires. Read Less

Gender:

ALL

Ages:

Between 6 years and 17 years

Trial Updated:

08/11/2025

Locations: Rehabilitation & Neurological Services /ID# 229969, Huntsville, Alabama +113 locations

Rehabilitation & Neurological Services /ID# 229969, Huntsville, Alabama

The Center for Clinical Trials - Saraland /ID# 231546, Saraland, Alabama

HealthStar Research of Hot Springs PLLC /ID# 273256, Hot Springs, Arkansas

Preferred Research Partners /ID# 230725, Little Rock, Arkansas

Advanced Research Center /ID# 227962, Anaheim, California

Neuro Pain Medical Center /ID# 227966, Fresno, California

Alliance for Research Alliance for Wellness /ID# 230546, Long Beach, California

Children's Hospital Los Angeles /ID# 230596, Los Angeles, California

Excell Research, Inc /ID# 230899, Oceanside, California

Paradigm Clinical Research - San Diego /ID# 269608, San Diego, California

Lumos Clinical Research Center /ID# 231267, San Jose, California

Pacific Clinical Research Management Group /ID# 231636, Upland, California

Sunwise Clinical Research /ID# 230971, Walnut Creek, California

Children's Hospital Colorado - Aurora /ID# 231879, Aurora, Colorado

IMMUNOe Research Centers /ID# 230879, Centennial, Colorado

MCB Clinical Research Centers /ID# 231625, Colorado Springs, Colorado

New England Institute for Clinical Research /ID# 230635, Stamford, Connecticut

Emerson Clinical Research Inst /ID# 231693, Washington, District of Columbia

Encore Medical Research of Boynton Beach LLC /ID# 246833, Boynton Beach, Florida

Gulf Coast Clinical Research Center /ID# 230020, Fort Myers, Florida

Sarkis Clinical Trials /ID# 227956, Gainesville, Florida

Northwest Florida Clinical Research Group, LLC /ID# 231069, Gulf Breeze, Florida

AGA Clinical Trials /ID# 230554, Hialeah, Florida

Encore Medical Research /ID# 245682, Hollywood, Florida

Advanced Research Institute of Miami /ID# 230292, Homestead, Florida

Auzmer Research /ID# 239251, Lakeland, Florida

Columbus Clinical Services, Llc /Id# 230880, Miami, Florida

My Preferred Research LLC /ID# 227886, Miami, Florida

Neurology & Pain Medicine /ID# 240168, Miami, Florida

Medical Research Group of Central Florida /ID# 231632, Orange City, Florida

Clinical Associates of Orlando, LLC /ID# 272619, Orlando, Florida

Suncoast Clinical Research - Palm Harbor /ID# 229337, Palm Harbor, Florida

Asclepes Research Centers - Spring Hill /ID# 229815, Spring Hill, Florida

University of South Florida- Neuroscience Institute /ID# 229324, Tampa, Florida

Encore Medical Research - Weston /ID# 246809, Weston, Florida

Pediatric Neurology and Epilepsy Specialists /ID# 229967, Winter Park, Florida

Treken Primary Care /ID# 240586, Atlanta, Georgia

Rare Disease Research, LLC /ID# 231046, Atlanta, Georgia

Clinical Integrative Research Center of Atlanta (CIRCA) /ID# 231134, Atlanta, Georgia

Coastal Georgia Child Neurology /ID# 231409, Brunswick, Georgia

CenExcel iResearch LLC /ID# 227903, Decatur, Georgia

Velocity Clinical Research - Savannah /ID# 228992, Savannah, Georgia

Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 231738, Stockbridge, Georgia

Velocity Clinical Research - Boise /ID# 231871, Meridian, Idaho

Chicago Headache Center & Research Institute /ID# 248625, Chicago, Illinois

Accellacare - McFarland Clinic /ID# 229789, Ames, Iowa

College Park Family Care Center Overland Park /ID# 231456, Overland Park, Kansas

Clinical Associates Midwest, LLC /ID# 274315, Overland Park, Kansas

Psychiatric Associates /ID# 230872, Overland Park, Kansas

Alliance for Multispecialty Research - Wichita East /ID# 234126, Wichita, Kansas

University of Kentucky Chandler Medical Center /ID# 230827, Lexington, Kentucky

Pharmasite Research, Inc. /ID# 227908, Baltimore, Maryland

Minneapolis Clinic of Neurology - Burnsville /ID# 232551, Burnsville, Minnesota

MediSync Clinical Research Hattiesburg Clinic /ID# 233326, Petal, Mississippi

Proven Endpoints LLC /ID# 239513, Ridgeland, Mississippi

Sharlin Health and Neurology /ID# 229523, Ozark, Missouri

Cognitive Clinical Trials (CCT) - Papillion /ID# 232552, Papillion, Nebraska

Healthy Perspectives - Innovative Mental Health Services, PLLC /ID# 230312, Nashua, New Hampshire

Hunterdon Neurology /ID# 245648, Annandale, New Jersey

Goryeb Children's Hospital /ID# 229507, Morristown, New Jersey

CVS HealthHUB - Runnemede /ID# 234233, Runnemede, New Jersey

Dent Neurologic Institute - Amherst /ID# 231182, Amherst, New York

Bioscience Research /ID# 232159, Mount Kisco, New York

Modern Migraine MD /ID# 258081, New York, New York

North Suffolk Neurology /ID# 230956, Port Jefferson Station, New York

SUNY Upstate Medical University /ID# 239898, Syracuse, New York

CVS HealthHUB - Charlotte /ID# 239530, Charlotte, North Carolina

OnSite Clinical Solutions, LLC - Hickory /ID# 227994, Hickory, North Carolina

Patient Priority Clinical Sites, LLC /ID# 238485, Cincinnati, Ohio

University Of Cincinnati Medical Center /ID# 231199, Cincinnati, Ohio

Cincinnati Childrens Hospital Medical Center /ID# 244689, Cincinnati, Ohio

Headache Center of Hope /ID# 242645, Cincinnati, Ohio

Centricity Research Columbus /ID# 231181, Columbus, Ohio

CincyScience /ID# 230046, West Chester, Ohio

IPS Research Company /ID# 227961, Oklahoma City, Oklahoma

Providence Brain and Spine Institute /ID# 231607, Portland, Oregon

Children's Hospital of Philadelphia - Main /ID# 232487, Philadelphia, Pennsylvania

Frontier Clinical Research, LLC - Scottdale /ID# 231913, Scottdale, Pennsylvania

Frontier Clinical Research - Smithfield /ID# 231912, Smithfield, Pennsylvania

Coastal Pediatric Research /ID# 238616, Charleston, South Carolina

Tribe Clinical Research LLC /ID# 230422, Greenville, South Carolina

Duplicate_Premier Neurology, P.C. /ID# 227999, Greer, South Carolina

Access Clinical Trials, Inc. /ID# 228002, Nashville, Tennessee

UT Health Austin at Dell Children's Neurology Clinic /ID# 244266, Austin, Texas

BioBehavioral Research of Austin /ID# 230529, Austin, Texas

Velocity Clinical Research, Austin /ID# 230557, Austin, Texas

Tekton Research - Beaumont /ID# 231207, Beaumont, Texas

Relaro Medical Trials /ID# 239642, Dallas, Texas

Cedar Health Research /ID# 228003, Dallas, Texas

3A Research - East El Paso /ID# 239193, El Paso, Texas

Earle Research /ID# 231548, Friendswood, Texas

DM Clinical Research /ID# 229826, Houston, Texas

Houston Clinical Research Associates /ID# 244889, Houston, Texas

Sante Clinical Research /ID# 246503, Kerrville, Texas

FMC Science /ID# 231915, Lampasas, Texas

Livingspring Family Medical Center /ID# 249869, Mansfield, Texas

AIM Trials /ID# 230142, Plano, Texas

Road Runner Research /ID# 230527, San Antonio, Texas

Family Psychiatry of The Woodlands /ID# 230163, The Woodlands, Texas

ClinPoint Trials /ID# 230295, Waxahachie, Texas

Pantheon Clinical Research /ID# 250703, Bountiful, Utah

Highland Clinical Research /ID# 239362, Salt Lake City, Utah

University of Utah Health Hospital /ID# 230908, Salt Lake City, Utah

Neuropsychiatric Associates LLC/DBA Woodstock Research Center /ID# 238976, Woodstock, Vermont

Office of Maria Ona /ID# 234232, Franklin, Virginia

Children's Hospital of The King's Daughters - Children's Medical Tower /ID# 230581, Norfolk, Virginia

National Clinical Research /ID# 231320, Richmond, Virginia

Core Clinical Research /ID# 227904, Everett, Washington

Frontier Clinical Research - Kingwood /ID# 231914, Kingwood, West Virginia

Mind+ Neurology /ID# 275529, Mequon, Wisconsin

Clinical Research Investigator Group, LLC /ID# 267454, Bayamon, Not set

Puerto Rico Health Institute /ID# 249162, Dorado, Not set

GCM Medical Group PSC /ID# 249643, San Juan, Not set

Caribbean Medical Research Center /ID# 265301, San Juan, Not set

Conditions: Migraine

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Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

NCT06972056

Recruiting

This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and propranolol. It will be determined if one works better and is more tolerable than the others. Research participants will: * Be randomly assigned to one of the three medications. * Provide information about their migraine pattern using a daily headache diary and during res... Read More

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

08/06/2025

Locations: Northern Arizona Healthcare, Flagstaff, Arizona +6 locations

Conditions: Migraine

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Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

NCT06417775

Recruiting

A migraine is a moderate to severe headache typically on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms. Menstrual migraine (MM) is defined as migraine attacks that occur within the perimenstrual period (PMP) in at least 2 out of 3 menstrual cycles. The PMP is from 2 days before the onset of menstrual bleeding to 2 days after. This study will assess how safe and effective ubrogepant i... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/04/2025

Locations: Central Research Associates /ID# 260161, Birmingham, Alabama +98 locations

Central Research Associates /ID# 260161, Birmingham, Alabama

Rehabilitation & Neurological Services /ID# 275593, Huntsville, Alabama

MD First Research - Chandler /ID# 262564, Chandler, Arizona

Gilbert Neurology /ID# 260179, Gilbert, Arizona

Foothills Research Center/CCT Research /ID# 260180, Phoenix, Arizona

Trialmed-Synexus Clinical Research US, Inc. - Tucson /ID# 258309, Tucson, Arizona

Preferred Research Partners /ID# 262786, Little Rock, Arkansas

Preferred Research Partners /ID# 273128, Little Rock, Arkansas

Hope Clinical Research /ID# 257867, Canoga Park, California

Axiom Research /ID# 257833, Colton, California

Neuro Pain Medical Center /ID# 257155, Fresno, California

Axiom Research, LLC-Los Angeles /ID# 264085, Glendale, California

Sun Valley Research Center /ID# 257152, Imperial, California

Axiom Research - Irvine /ID# 264083, Irvine, California

Collaborative Neuroscience Research CNS /ID# 257828, Los Alamitos, California

Los Angeles Headache Center /ID# 257237, Los Angeles, California

Pharmacology Research Institute (PRI) - Newport Beach (Wake) /ID# 257158, Newport Beach, California

Artemis Institute for Clinical Research - San Diego /ID# 257134, San Diego, California

WR - Medical Center for Clinical Research /ID# 257897, San Diego, California

Optimus Medical /ID# 257856, San Francisco, California

New England Institute for Clinical Research /ID# 264019, Stamford, Connecticut

Neurology Offices of South Florida, PLLC /ID# 257161, Boca Raton, Florida

Accel Research Sites Network - DeLand Clinical Research Unit /ID# 257403, DeLand, Florida

Accel Research Sites - Lakeland Clinical Research Unit /ID# 257874, Lakeland, Florida

Well Pharma Medical Research /ID# 257199, Miami, Florida

Sensible Healthcare /ID# 257198, Ocoee, Florida

Clinical Neuroscience Solutions, Inc /ID# 257190, Orlando, Florida

Conquest Research /ID# 258314, Winter Park, Florida

NeuroTrials Research /ID# 274507, Atlanta, Georgia

Clinical Research Atlanta - Headlands LLC /ID# 260181, Stockbridge, Georgia

Hawaii Pacific Neuroscience /ID# 274469, Honolulu, Hawaii

Velocity Clinical Research - Boise /ID# 257135, Meridian, Idaho

Healthcare Research Network /ID# 257868, Flossmoor, Illinois

Deaconess Midtown Hospital /ID# 257400, Evansville, Indiana

Accellacare - McFarland Clinic /ID# 257834, Ames, Iowa

Alliance for Multispecialty Research LLC /ID# 257839, Newton, Kansas

Collective Medical Research /ID# 257131, Overland Park, Kansas

Alliance for Multispecialty Research - Wichita East /ID# 257148, Wichita, Kansas

Tandem Clinical Research - Marrero - Barataria Boulevard /ID# 260146, Marrero, Louisiana

IMA Clinical Research Monroe - Wood /ID# 259362, Monroe, Louisiana

Headlands PharmaSite /ID# 257208, Baltimore, Maryland

Boston Clinical Trials /ID# 257132, Boston, Massachusetts

BTC of New Bedford /ID# 257128, New Bedford, Massachusetts

MedVadis Research /ID# 257156, Waltham, Massachusetts

Michigan Headache & Neurological Institute (MHNI) /ID# 257179, Ann Arbor, Michigan

Proven Endpoints LLC /ID# 273796, Ridgeland, Mississippi

HealthCare Research Network - Hazelwood /ID# 257402, Hazelwood, Missouri

Clinvest Research LLC /ID# 257215, Springfield, Missouri

Methodist Physicians Clinic/CCT Research /ID# 260167, Fremont, Nebraska

Cognitive Clinical Trials (CCT) - Papillion /ID# 260174, Papillion, Nebraska

IMA Clinical Research Las Vegas /ID# 258679, Las Vegas, Nevada

Wr-Crcn, Llc /Id# 257895, Las Vegas, Nevada

Bio Behavioral Health, Inc /ID# 257140, Toms River, New Jersey

IMA Clinical Research Warren /ID# 263641, Warren, New Jersey

Albuquerque Clinical Trials, Inc. /ID# 257212, Albuquerque, New Mexico

Dent Neurologic Institute - Amherst /ID# 257219, Amherst, New York

IMA Clinical Research Westchester /ID# 259157, Hartsdale, New York

Fieve Clinical Research, Inc. /ID# 257177, New York, New York

Rochester Clinical Research /ID# 257193, New York, New York

Upstate Clinical Research Associates /ID# 257163, Williamsville, New York

Headache Wellness Center /ID# 257136, Greensboro, North Carolina

Accellacare /ID# 257731, Winston-Salem, North Carolina

Accellacare /ID# 257850, Winston-Salem, North Carolina

Lillestol Research, LLC /ID# 257896, Fargo, North Dakota

CTI Clinical Research Center /ID# 257162, Cincinnati, Ohio

C7 Research /ID# 272815, Cleveland, Ohio

Centricity Research Columbus /ID# 257221, Columbus, Ohio

Wright State Physicians Health Center /ID# 274708, Fairborn, Ohio

Lynn Institute of Oklahoma City /ID# 257857, Oklahoma City, Oklahoma

Summit Research Network - Portland - Northwest Vaughn Street /ID# 257139, Portland, Oregon

Abington Neurological Associates - Abington /ID# 257164, Abington, Pennsylvania

Clinical Research of Philadelphia, LLC /ID# 257197, Philadelphia, Pennsylvania

Partners In Clinical Research /ID# 257855, Cumberland, Rhode Island

Premier Neurology /ID# 260359, Greenville, South Carolina

Coastal Carolina Research Center - North Charleston /ID# 257227, North Charleston, South Carolina

WR-ClinSearch /ID# 257160, Chattanooga, Tennessee

KCA Neurology /ID# 274495, Franklin, Tennessee

Alliance for Multispecialty Research - Knoxville /ID# 257846, Knoxville, Tennessee

FutureSearch Trials of Neurology /ID# 257186, Austin, Texas

FutureSearch Trials of Dallas, LP /ID# 257142, Dallas, Texas

Houston Clinical Research Associates /ID# 272077, Houston, Texas

Red Star Research, LLC /ID# 257871, Lake Jackson, Texas

Radiance Clinical Research /ID# 271727, Lampasas, Texas

Epic Clinical Research - Lewisville /ID# 274480, Lewisville, Texas

Elevate Clinical - Seabrook /ID# 274679, Seabrook, Texas

Clinpoint Trials /ID# 274524, Waxahachie, Texas

Advanced Research Institute /ID# 257853, Ogden, Utah

J. Lewis Research, Inc. / Foothill Family Clinic South /ID# 258305, Salt Lake City, Utah

Highland Clinical Research /ID# 257137, Salt Lake City, Utah

Charlottesville Medical Research /ID# 257154, Charlottesville, Virginia

Alliance for Multispecialty Research - Clinical Research Associates /ID# 257851, Norfolk, Virginia

Northwest Clinical Research Center /ID# 257381, Bellevue, Washington

Puget Sound Neurology /ID# 257174, Tacoma, Washington

Vaught Neurological Services /ID# 267519, Beckley, West Virginia

West Virginia Univ School Med /ID# 258898, Morgantown, West Virginia

Mind+ Neurology /ID# 274486, Mequon, Wisconsin

ISIS Clinical Research Center /ID# 262858, Guaynabo, Not set

Instituto De Neurologia Dra. Ivonne Fraga, Psc /ID# 262852, San Juan, Not set

BDH Research /ID# 262851, San Juan, Not set

Conditions: Migraine

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Mechanistic Studies of Psilocybin in Headache Disorders

NCT06464367

Recruiting

In previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin. This purpose of this study is to examine potential sources for this observed effect. This study will measure brain resting state functional connectivity (fMRI), central synaptic density (SV2A PET), peripheral markers of inflammation, circadian rhythm (actigraphy), and sleep (sleep EEG) in both migraine and healthy control participants before and one week after the... Read More

Gender:

ALL

Ages:

Between 21 years and 70 years

Trial Updated:

07/21/2025

Locations: VA Connecticut Healthcare System, West Haven, Connecticut

Conditions: Migraine

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Evaluation of a Wearable Device for Acute Treatment of Migraines

NCT07015125

Recruiting

The goal of this clinical trial is to determine the efficacy of a new, improved neuromodulation device that can be worn on the head and neck to relieve migraine pain. To measure efficacy, investigators will compare how measured outcomes resulting from active stimulation with this device compare to those of sham treatment.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/10/2025

Locations: Hinge Health, Inc., San Francisco, California

Conditions: Migraine, Migraine With or Without Aura, Migraine, Acute, Migraine Headache

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Cocoa Extract for Migraine Trial

NCT06808230

Recruiting

The goal of this clinical trial is to assess the feasibility of recruitment and adherence to a high-dose cocoa extract supplement in individuals diagnosed with episodic migraine. The main questions it aims to answer are: * Will we be able to enroll 114 participants during the recruitment period? * Will participants take study pills daily during the pill-taking period? Researchers will compare two doses of cocoa extract to placebo to determine the acceptability of higher doses of cocoa extract... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/09/2025

Locations: Brigham and Women's Hospital, Boston, Massachusetts

Conditions: Migraine

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Bilateral Middle Meningeal Artery Lidocaine Infusion for Chronic Debilitating Migraines

NCT07061847

Recruiting

The main purpose of this study is to evaluate the effectiveness of a new treatment in improving chronic migraine symptoms. This treatment involves a targeted lidocaine infusion into blood vessels in the skull to numb pain receptors, potentially leading to improvements in chronic migraine intensity, frequency, and duration.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

07/01/2025

Locations: Neuroscience Institute at Great Neck, Great Neck, New York

Conditions: Migraine

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