There are currently 51 active clinical trials seeking participants for Migraine research studies. The states with the highest number of trials for Migraine participants are Florida, California, Texas and New York.
A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
NCT06473597
Recruiting
Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine. Rizatriptan benzoate (MAXALT), is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist. Rizatriptan binds with high affinity to human cloned 5-HT1B and 5-HT1D receptors which leads to activation of these receptors results in cranial vessel constriction, inhibition of neuropeptide release and reduced transmission in trigeminal pain pathways with resu... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/27/2024
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Migraine
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Treatment for Migraine and Mood
NCT05576467
Recruiting
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: Albert Einstein College of Medicine, Bronx, New York +2 locations
Conditions: Migraine, Depressive Symptoms
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Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications
NCT06401642
Recruiting
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Mayo Clinic in Arizona, Phoenix, Arizona
Conditions: Migraine
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Mindfulness-Based Intervention for Adolescents With Chronic Migraine
NCT06414109
Recruiting
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on headache-related outcomes.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
07/08/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Migraine, Migraine in Adolescence
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Objectively Diagnose and Monitor Treatment of Light Sensitivity
NCT03694626
Recruiting
The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and autonomic nerve responses to light.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/15/2024
Locations: University of Iowa Health Care, Iowa City, Iowa
Conditions: Photophobia, Traumatic Brain Injury, Migraine
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Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
NCT06173661
Recruiting
The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period. The study includes people ages 18 to 45 who have been diagnosed with migraine and who have a migraine with their menstrual period or those who have migraines with their menstrual period and at other times of the month as well. The main question the study aims to answer are: • Does fremanazemab, an injectable calcitonin gene-related pept... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
05/14/2024
Locations: Brigham and Women's Health Care Center, Chestnut Hill, Massachusetts
Conditions: Migraine, Menstrual Migraine, Menstrually Related Migraine
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Responding With Evidence and Access for Childhood Headaches
NCT05889624
Recruiting
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the feasibility of Cognitive Behavioral Therapy (CBT) via telehealth for youth with migraine. The focus is on applying evidence-based care and enhancing access to it. CBT via telehealth while taking a clinically-prescribed, pill-based prevention therapy (amitriptyline) will b... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
05/13/2024
Locations: University of Alabama at Birmingham Children's of Alabama, Birmingham, Alabama +13 locations
Conditions: Headache, Headache Disorders, Headache, Migraine, Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Chronic Migraine
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Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
NCT04930887
Recruiting
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion. We aim to investigate whether the administration of Exparel (Bupivacaine) to the lateral nasal wall may pos... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2024
Locations: Peter H Hwang, Stanford, California
Conditions: Craniofacial Pain, Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Sphenopalatine Ganglion Neuralgia, Paroxysmal Hemicrania
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Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial
NCT06170281
Recruiting
This study will unpack the behavioral intervention for migraine and determine the optimum combinations. In addition, the study will test preference and self-selection effects during the trial.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: Stanford University, Stanford, California
Conditions: Migraine, Headache, Chronic Migraine, Headache Disorders
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Emgality for Migraine in Breastmilk
NCT06085144
Recruiting
The goal of this project is to evaluate galcanezumab transfer into maternal breastmilk, and to evaluate infant (growth, development, constipation, colic, infections) and maternal (headache) outcomes for dyads in which the mother was treated with galcanezumab and to compare outcomes for infants who were or were not breastfed after maternal treatment. In this prospective observational study, the study team proposes to prospectively collect serial milk samples from 30 adult women who are treated w... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
11/28/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Migraine
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Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
NCT06016465
Recruiting
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
09/26/2023
Locations: University Medical Center of El Paso, El Paso, Texas
Conditions: Migraine
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EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines
NCT04607460
Recruiting
The purpose of this pilot efficacy study is to examine the effects of EMG-biofeedback (EMG-BF) on pain-related outcomes in Chronic Low Back Pain (CLBP) patients, Recent mastectomy and lumpectomy patients, and patients with episodic migraine. EMG-BF facilitates neuromuscular retraining and muscle relaxation by using audio and visual stimuli using an EMG surface electrode-based biosensor and a software installed on a tablet or smart phone. For this pilot efficacy study, we will recruit 125 patie... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/11/2023
Locations: Brigham and Women's Hospital, Chestnut Hill, Massachusetts
Conditions: Chronic Low-back Pain, Mastectomy, Lumpectomy, Migraine
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