There are currently 51 active clinical trials seeking participants for Migraine research studies. The states with the highest number of trials for Migraine participants are Florida, California, Texas and New York.
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
NCT06624137
Recruiting
The goal of this observational study is to learn how the brain's information processing changes during and following administration of serotonergic psychedelics (psilocybin, N,N-Dimethyltryptamine/DMT, Lystergic Acid Diethylamide/LSD, etc.) for people with and without mental illness receiving serotonergic psychedelics through any clinical trial at Yale University. The main questions it aims to answer are: 1. Do serotonergic psychedelics cause the brain to rely on new information more than previ... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/12/2024
Locations: Connecticut Mental Health Center, Hamden, Connecticut +1 locations
Conditions: OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
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RELAXaHEAD for Headache Patients (Phase III)
NCT06077838
Recruiting
This study is a fully powered, remote randomized control trial to evaluate RELAXaHEAD in people with migraine.
Gender:
ALL
Ages:
Between 16 years and 80 years
Trial Updated:
10/08/2024
Locations: NYU Langone Health, New York, New York
Conditions: Migraine
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Aimovig Pregnancy Exposure Registry
NCT06150781
Recruiting
The primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of women with migraine unexposed to erenumeb-aooe.
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
10/02/2024
Locations: IQVIA Virtual Site, Durham, North Carolina
Conditions: Migraine
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A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
NCT06473597
Recruiting
Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine. Rizatriptan benzoate (MAXALT), is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist. Rizatriptan binds with high affinity to human cloned 5-HT1B and 5-HT1D receptors which leads to activation of these receptors results in cranial vessel constriction, inhibition of neuropeptide release and reduced transmission in trigeminal pain pathways with resu... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/27/2024
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Migraine
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Treatment for Migraine and Mood
NCT05576467
Recruiting
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: Albert Einstein College of Medicine, Bronx, New York +2 locations
Conditions: Migraine, Depressive Symptoms
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Overlapping Pain Trajectory Study
NCT05752396
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/20/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
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Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications
NCT06401642
Recruiting
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Mayo Clinic in Arizona, Phoenix, Arizona
Conditions: Migraine
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Mindfulness-Based Intervention for Adolescents With Chronic Migraine
NCT06414109
Recruiting
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on headache-related outcomes.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
07/08/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Migraine, Migraine in Adolescence
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Objectively Diagnose and Monitor Treatment of Light Sensitivity
NCT03694626
Recruiting
The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and autonomic nerve responses to light.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/15/2024
Locations: University of Iowa Health Care, Iowa City, Iowa
Conditions: Photophobia, Traumatic Brain Injury, Migraine
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Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
NCT06173661
Recruiting
The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period. The study includes people ages 18 to 45 who have been diagnosed with migraine and who have a migraine with their menstrual period or those who have migraines with their menstrual period and at other times of the month as well. The main question the study aims to answer are: • Does fremanazemab, an injectable calcitonin gene-related pept... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/14/2024
Locations: Brigham and Women's Health Care Center, Chestnut Hill, Massachusetts
Conditions: Migraine, Menstrual Migraine, Menstrually Related Migraine
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Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
NCT04930887
Recruiting
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion. We aim to investigate whether the administration of Exparel (Bupivacaine) to the lateral nasal wall may pos... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2024
Locations: Peter H Hwang, Stanford, California
Conditions: Craniofacial Pain, Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Sphenopalatine Ganglion Neuralgia, Paroxysmal Hemicrania
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Migraine Manager (R01)
NCT04567355
Recruiting
The objective of this trial is to test whether an online tailored intervention, Migraine Manager, is efficacious in improving headache outcomes compared to an attention control intervention in adolescents with migraines. We will conduct a randomized clinical trial to compare a sample of 80 youth (ages 11 to 17) with migraine receiving the online tailored adherence intervention to 80 youth in an attention control group. We will test whether adherence to healthy habit (hydration, regular meals, ex... Read More
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
03/25/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Migraine, Migraine Disorders
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