There are currently 57 active clinical trials seeking participants for Rheumatoid Arthritis research studies. The states with the highest number of trials for Rheumatoid Arthritis participants are Florida, California, Texas and Pennsylvania.
Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System
NCT03626038
Recruiting
This study is a multicenter, prospective, non-randomized, non-controlled post-market clinical follow-up study. The primary objective of this study is to confirm the safety and performance of the A.L.P.S. Proximal Humerus Plating System applied in proximal humerus fracture treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: Foundation for Orthopaedic Research & Education, Tampa, Florida +1 locations
Conditions: Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Psoriatic Arthritis, Proximal Humeral Fracture
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Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis
NCT05363891
Recruiting
Phase II, Double-Blind, Placebo-Controlled, Randomized Trial Examining Natrunix in Combination with MTX (+Folate) for the Treatment of Rheumatoid Arthritis
Gender:
All
Ages:
18 years and above
Trial Updated:
12/08/2023
Locations: Accurate Clinical Research Inc, Lake Charles, Louisiana +2 locations
Conditions: Rheumatoid Arthritis
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Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease
NCT03297775
Recruiting
The overall goal of this study is to define the phenotype of Interstitial Lung Disease (ILD), and identify factors that predict radiologic progression in those with subclinical RA-ILD, in patients with rheumatoid arthritis (RA). The investigators hypothesize that there are common core elements (e.g. clinical features, genetic variants, and/or biologic markers) between other forms of ILD (e.g. idiopathic pulmonary fibrosis, IPF) and subclinical RA-ILD that places individuals at risk for the devel... Read More
Gender:
All
Ages:
Between 45 years and 90 years
Trial Updated:
11/28/2023
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Rheumatoid Arthritis, Interstitial Lung Disease
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Comparative Pharmacokinetic Study of Three Abatacept Products in Male Normal Healthy Volunteers by the Subcutaneous Route
NCT06126042
Recruiting
This is a randomised, double-blind, single dose, parallel groups study to compare the PK, immunogenicity, and safety of 3 abatacept products (DRL_AB, RP and RMP) in male NHV.
Gender:
Male
Ages:
Between 18 years and 50 years
Trial Updated:
11/08/2023
Locations: ICON, plc., Lenexa, Kansas +2 locations
Conditions: Rheumatoid Arthritis
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COVID-19 VaccinE Response in Rheumatology Patients
NCT05080218
Recruiting
The COVID-19 VaccinE Response in Rheumatology patients (COVER) study is a multicenter randomized controlled trial designed to evaluate the efficacy and safety of a mRNA COVID-19 vaccine supplemental dose (booster) in patients with autoimmune conditions and to evaluate the impact of different immunomodulatory therapies on vaccine response. The investigators propose to recruit up to 1000- patients with autoimmune conditions who have a completed 2-dose regime of mRNA COVID-19 vaccine (>28 days prio... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama +7 locations
Conditions: Rheumatoid Arthritis, Psoriatic Arthritis, Spondylarthritis
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A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
NCT06041269
Recruiting
RENOIR Study: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe Rheumatoid Arthritis (RA)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2023
Locations: Anaptys Bio Investigative Site 10-132, Flagstaff, Arizona +88 locations
Conditions: Rheumatoid Arthritis
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MAD Study of IA-14069
NCT05533372
Recruiting
The purpose of this study is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending oral doses of IA-14069 in healthy subjects and in patients with RA on stable dosese of MTX, with preliminary assessment of efficacy in RA patients.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/11/2023
Locations: ICON plc., Lenexa, Kansas
Conditions: Healthy, Rheumatoid Arthritis
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Rheumatoid Arthritis Shared Decision Making
NCT05530694
Recruiting
Shared decision making is the first overarching principle for the treat to target guidelines for rheumatoid arthritis (RA) and has been proposed as a potential mechanism to reduce health disparities, however there is little evidence to inform effective ways to implement this practice in the care of Veterans with RA. The purpose of this project is to evaluate the effectiveness of a multi-component shared decision making intervention on RA disease activity, adherence to RA medications and patient... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: San Francisco VA Medical Center, San Francisco, CA, San Francisco, California +2 locations
Conditions: Rheumatoid Arthritis
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Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
NCT04488497
Recruiting
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk for heart attacks and strokes. This project will build the foundation for an intervention that will test the hypothesis that the patient-centered intervention tailored to patients with RA to improve hyperlipidemia screening and treatment, thereby decreasing the risk for... Read More
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
08/17/2023
Locations: Weill Cornell Medicine, New York, New York
Conditions: Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
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Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis
NCT05291299
Recruiting
The primary objective of this study is to assess if there is a significant difference in the mean disease activity score in individuals with RA participating in a dietary intervention compared to those in the control group measured by DAS-28. Other measures to track disease activity will include monitoring number and severity of disease flares and any changes in medications. This will be done by completing a single-blinded randomized controlled trial, parallel in design. The study population wil... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Attune Health Research Inc, Beverly Hills, California
Conditions: Rheumatoid Arthritis
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Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis
NCT05460390
Recruiting
Current standard of care of rheumatoid arthritis (RA) management includes a routine clinical assessment of disease activity to adjust therapy. For the most part, therapy adjustment for therapy non-response and/or suboptimal therapy response leads to therapy switch within the same class of therapy or to a different class of therapy. The lack of objective data to titrate dose of a given therapeutic agent for maximal possible efficacy makes it difficult for providers and payors to titrate dose as n... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: Boston Medical Center, Rheumatology Clinic, Boston, Massachusetts
Conditions: Rheumatoid Arthritis
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OTIS Autoimmune Diseases in Pregnancy Project
NCT01797224
Recruiting
The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for five years after birth. With respect to fetal outcome, it is important to evaluate the spectrum of outcomes that may be relevant to a medication exposure during pregnancy, and these include both easily recognizable defects which are visible at birth, as we... Read More
Gender:
Female
Ages:
All
Trial Updated:
05/22/2023
Locations: University of California, San Diego, San Diego, California
Conditions: Crohn's Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
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