There are currently 59 active clinical trials seeking participants for Rheumatoid Arthritis research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and Pennsylvania.
Dietary Salt in Rheumatoid Arthritis
Recruiting
In this study investigators propose to address the following hypotheses: 1) Reduction in dietary sodium will decrease inflammation in patients with rheumatoid arthritis (RA). 2) Reduction in dietary sodium will decrease blood pressure in patients with RA. 3) Reduction in dietary sodium will decrease tissue sodium in patients with RA.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/27/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Rheumatoid Arthritis
Prospective, Multi-Center, Observational, Whole Blood Specimen Collection Study in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to bDMARD or tsDMARD +/- csDMARD Changing Treatment to a bDMARD or tsDMARD Treatment +/- csDMARD
Recruiting
The primary goal of this study is to assess a cfDNA-based blood test using genetic, transcriptomic and/or epigenetic information to help doctors predict the best treatment options for rheumatoid arthritis (RA) patients with inadequate response or intolerance to previous therapies.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Arthritis and Osteoporosis Consultants of the Carolinas, Charlotte, North Carolina
Conditions: Rheumatoid Arthritis
Dynamic Treatment Regiments for Glucocorticoid Tapering
Recruiting
The purpose of this clinical trial is to better understand how people with rheumatoid arthritis (RA) respond to gradual dose reduction, or "tapering", of steroid medications like prednisone. Some people with RA have symptoms when steroid dose is reduced, while others don't. This trial will look at different patient characteristics, including levels of inflammation in the body, differences in the way the brain processes sensory information, and certain hormone levels, to help researchers better u... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/16/2023
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan
Conditions: Rheumatoid Arthritis
A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
Recruiting
RENOIR Study: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe Rheumatoid Arthritis (RA)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2023
Locations: Anaptys Bio Investigative Site 10-132, Flagstaff, Arizona +88 locations
Conditions: Rheumatoid Arthritis
MAD Study of IA-14069
Recruiting
The purpose of this study is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending oral doses of IA-14069 in healthy subjects and in patients with RA on stable dosese of MTX, with preliminary assessment of efficacy in RA patients.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/11/2023
Locations: ICON plc., Lenexa, Kansas
Conditions: Healthy, Rheumatoid Arthritis
Rheumatoid Arthritis Shared Decision Making
Recruiting
Shared decision making is the first overarching principle for the treat to target guidelines for rheumatoid arthritis (RA) and has been proposed as a potential mechanism to reduce health disparities, however there is little evidence to inform effective ways to implement this practice in the care of Veterans with RA. The purpose of this project is to evaluate the effectiveness of a multi-component shared decision making intervention on RA disease activity, adherence to RA medications and patient... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: San Francisco VA Medical Center, San Francisco, CA, San Francisco, California +2 locations
Conditions: Rheumatoid Arthritis
Early Rheumatoid Arthritis Lung Disease Study
Recruiting
The primary goal of this study is to investigate lung disease, through pulmonary function and high resolution chest CT, in newly diagnosed RA patients. Extra-articular disease occurs in approximately 50% of RA patients, with the lung being a common site of involvement. Investigators goal is to understand the prevalence of lung disease in early RA patients and to better characterize it through questionnaires, imaging, and serum studies. Additionally, the goal is to find novel biomarkers to predi... Read More
Gender:
All
Ages:
Between 19 years and 90 years
Trial Updated:
09/29/2023
Locations: University of Nebraska Medical Center, Omaha, Nebraska
Conditions: Rheumatoid Arthritis
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Recruiting
This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibility, and content of the tool. Researchers will use the information collected to improve the educational materials that will help patients make future decisions about their treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease, Inflammatory Bowel Disease, Melanoma, Psoriasis, Psoriatic Arthritis, Reactive Arthritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Ulcerative Colitis, Enteropathic Arthritis, Enteropathic Spondylitis
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
Recruiting
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk for heart attacks and strokes. This project will build the foundation for an intervention that will test the hypothesis that the patient-centered intervention tailored to patients with RA to improve hyperlipidemia screening and treatment, thereby decreasing the risk for... Read More
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
08/17/2023
Locations: Weill Cornell Medicine, New York, New York
Conditions: Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
Effect of Anti-inflammatory Diet in Rheumatoid Arthritis
Recruiting
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: UCSD, La Jolla, California
Conditions: Rheumatoid Arthritis
Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis
Recruiting
The primary objective of this study is to assess if there is a significant difference in the mean disease activity score in individuals with RA participating in a dietary intervention compared to those in the control group measured by DAS-28. Other measures to track disease activity will include monitoring number and severity of disease flares and any changes in medications. This will be done by completing a single-blinded randomized controlled trial, parallel in design. The study population wil... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Attune Health Research Inc, Beverly Hills, California
Conditions: Rheumatoid Arthritis
Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis
Recruiting
Current standard of care of rheumatoid arthritis (RA) management includes a routine clinical assessment of disease activity to adjust therapy. For the most part, therapy adjustment for therapy non-response and/or suboptimal therapy response leads to therapy switch within the same class of therapy or to a different class of therapy. The lack of objective data to titrate dose of a given therapeutic agent for maximal possible efficacy makes it difficult for providers and payors to titrate dose as n... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: Boston Medical Center, Rheumatology Clinic, Boston, Massachusetts
Conditions: Rheumatoid Arthritis