There are currently 59 active clinical trials seeking participants for Rheumatoid Arthritis research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and Pennsylvania.
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
OTIS Autoimmune Diseases in Pregnancy Project
Recruiting
The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for five years after birth. With respect to fetal outcome, it is important to evaluate the spectrum of outcomes that may be relevant to a medication exposure during pregnancy, and these include both easily recognizable defects which are visible at birth, as we... Read More
Gender:
Female
Ages:
All
Trial Updated:
05/22/2023
Locations: University of California, San Diego, San Diego, California
Conditions: Crohn's Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)
Recruiting
Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities. They established reliable and reproducible methodologies in RA patients. The purpose of this phase 2 pilot is to study RA disease progression and effectiveness as well as the mechanism of action of clinical interventions using established NIR-ICG methodologies in previous studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: University of Rochester, Rochester, New York
Conditions: Rheumatoid Arthritis
Physica System Total Knee Replacement Registry Study
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: Eisenhower Desert Orthopedics Center - Harry and Diane Rinker Bldg, Rancho Mirage, California +4 locations
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
The ArthritisPower Wearable Study
Recruiting
Rheumatoid arthritis patients being seen at one of the participating clinical sites in a U.S. network of community rheumatology practices who are starting treatment on adalimumab or upadacitinib will be enrolled into a 24-week study combining clinical data from physicians, self-reported patient outcomes from the ArthritisPower registry app, and activity and sleep data from a Fitbit wearable device. The primary objective of this study is: • Evaluate longitudinal associations between biometric s... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
10/27/2022
Locations: Global Healthy Living Foundation, Upper Nyack, New York
Conditions: Rheumatoid Arthritis
Sputum Studies of Anti-Citrullinated Protein Antibodies (ACPA) and Rheumatoid Arthritis (RA) Origins
Recruiting
The study is designed to learn more about the causes of rheumatoid arthritis (RA). People who get RA have elevated protein markers called autoantibodies in their blood years before initial symptoms of arthritis. The goal of this study is to learn more about how autoantibodies in RA might be related to inflammation in the lungs.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/13/2022
Locations: University of Colorado Denver (Anschutz Medical Campus), Aurora, Colorado
Conditions: Rheumatoid Arthritis
Novel Form of Acquired Long QT Syndrome
Recruiting
The goal of this study is to determine whether anti-Ro/SSA antibodies are associated with acquired QT prolongation in subjects with connective tissue disease. The investigators will investigate whether gender or race influence correlation between anti-Ro antibody status and prolonged QT interval and the role of inflammatory cytokines in association with anti-Ro antibodies and QT prolongation. The investigators propose to add an additional objective to test whether QT prolongation is reversible w... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/07/2022
Locations: VA New York Harbor Healthcare System, NY and Brooklyn Campuses, New York, New York
Conditions: Long QT Syndrome, Connective Tissue Diseases, Rheumatoid Arthritis
Delivery of Enhance Fitness Trial
Recruiting
Arthritis is a common condition in the United States, and a leading cause of pain and disability. Physical exercise is recommended for managing arthritis, but access to evidence-based exercise programs is limited, particularly in rural areas. Therefore, the investigators propose to evaluate remote delivery of an evidence-based exercise program called Enhance Fitness (EF) that is recommended for arthritis management. The primary purpose of this study is to determine if remotely delivered EF is no... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2022
Locations: University of Washington, Seattle, Washington
Conditions: Arthritis, Rheumatoid Arthritis, Fibromyalgia, Gout, Osteoarthritis, Lupus or SLE
Survivorship and Patient Outcomes of Primary Total Hip Arthroplasty With the Ovation Hip System
Recruiting
The objective of this study is to evaluate patient outcomes in regards to safety and effectiveness based on the clinical performance of the reference devices to further support the assessment of residual risk identified in the Clinical Evaluation Report for the Ortho Development Hip System.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/13/2019
Locations: Straub Medical Center, Honolulu, Hawaii
Conditions: Joint Diseases, Osteoarthritis, Hip, Rheumatoid Arthritis, Psoriatic Arthritis, Avascular Necrosis of Hip
Investigate the Development and Progression of Lung Disease in Rheumatoid Arthritis Over Time
Recruiting
The purpose of this study is to investigate the link between the lungs and rheumatoid arthritis (RA). Additionally, to understand why RA patients get lung disease, how to treat, and prevent the disease.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: Rheumatoid Arthritis, Lung Diseases
NSAIDs vs. Coxibs in the Presence of Aspirin
Recruiting
The objectives of this single site, randomized, crossover study is to evaluate the pharmacodynamic interactions between aspirin, NSAIDs and Coxibs with respect to platelet function, biomarkers of inflammation and endothelial function.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
10/04/2018
Locations: Inova Heart and Vascular Institute, Falls Church, Virginia
Conditions: Rheumatoid Arthritis, Cardiovascular Diseases