There are currently 77 active clinical trials seeking participants for Ulcerative Colitis research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and New York.
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
Recruiting
This research study is testing whether changes in sleep timing and morning light treatment may have an impact on symptoms related to inflammatory bowel disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treated with tilpisertib fosmecarbil with participants treated with placebo. The primary objective of this study is to demonstrate the efficacy of tilpisertib fosmecarbil, compared to placebo control, in achieving Clinical Response at Week 12.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/09/2024
Locations: Arizona Digestive Health, Sun City, Arizona +46 locations
Conditions: Ulcerative Colitis
Aquamin® as an Adjuvant Intervention for Ulcerative Colitis
Recruiting
The purpose of this study is to determine if Aquamin® works as a potential treatment to improve symptoms and if it will induce remission in patients with mild Ulcerative Colitis and extend remission in Ulcerative Colitis in remission.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/05/2024
Locations: The University of Michigan, Ann Arbor, Michigan
Conditions: Ulcerative Colitis
GI Permeability Change in Response to Aquamin®
Recruiting
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/05/2024
Locations: University of Michigan Hospital, Ann Arbor, Michigan
Conditions: Healthy, Ulcerative Colitis, Irritable Bowel Syndrome With Diarrhea
A Phase 1b Proof-of-concept Trial Exploring the Effects of FE 999322 and FE 999324 in Adults With Mild to Moderate Ulcerative Colitis
Recruiting
To explore the safety of FE 999322 (microbiota suspension) and FE 999324 (microbiota capsule) versus placebo in subjects with active mild to moderate ulcerative colitis (UC).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Ferring Investigational Site, North Little Rock, Arkansas +2 locations
Conditions: Ulcerative Colitis
An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis
Recruiting
The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blind treatment (either etrasimod 2 mg per day or placebo) during participation in one of the qualified Phase 3 or Phase 2 double-blind, placebo-controlled parent studies including but not limited to: (APD334-301 [NCT03945188] or APD334-302 [NCT03996369] or APD334-210 [NCT04607837]).
Gender:
All
Ages:
Between 16 years and 80 years
Trial Updated:
04/02/2024
Locations: Center for Digestive Health (Colonoscopy Location), Dothan, Alabama +619 locations
Conditions: Ulcerative Colitis
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Recruiting
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years up to < 18 years of age). Participants who will complete the total 52-week treatment period will have the opportunity to continue in a Long-Term Extension (LTE) Period of up to 4 years (5 years after study enrollment), or until marketing authorization is obtained in the participant's country, whiche... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
04/02/2024
Locations: Valley View Wellness Medical Center, Garden Grove, California +49 locations
Conditions: Ulcerative Colitis
VE202 in Patients With Mild-to-Moderate Ulcerative Colitis
Recruiting
A Phase 2 study to evaluate the safety, efficacy, and microbiota changes of VE202 in patients with mild to moderate ulcerative colitis (UC).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/29/2024
Locations: Digestive Health Specialists, Dothan, Alabama +52 locations
Conditions: Ulcerative Colitis, Colitis, Ulcerative
Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis
Recruiting
Phase 2 induction study with a long-term extension (LTE) period in participants with moderate to severe ulcerative colitis (UC).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/13/2024
Locations: Orlando Health, Inc., Orlando, Florida +31 locations
Conditions: Ulcerative Colitis
Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The primary objective of this study is to evaluate the long-term safety and tolerability of efavaleukin alfa in participants with moderate to severe ulcerative colitis (UC).
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/13/2024
Locations: Santa Maria Gastroenterology Medical Group, Santa Maria, California +22 locations
Conditions: Ulcerative Colitis
Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis
Recruiting
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how safe and effective ABBV-668 is in treating adult participants with UC. Adverse events and change in disease activity will be assessed. ABBV-668 is an investigational drug being developed for the treatment of moderate to severe UC. Approximately 40 adult participants diagnosed with UC will be enrolled in approx... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Gastro SB /ID# 249271, Chula Vista, California +29 locations
Conditions: Ulcerative Colitis
A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
A study to investigate bowel urgency in adults with moderately to severely active ulcerative colitis (UC) treated with mirikizumab. The study will have 4 periods and will last for 36 weeks.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: East View Medical Research, LLC, Mobile, Alabama +153 locations
Conditions: Ulcerative Colitis, Ulcerative Colitis Chronic