The state of Florida currently has 43 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
Characterizing the Scalp Tolerability of TMS
NCT06354686
Recruiting
The primary objective is to characterize the tolerability of TMS by scalp location (over parietal, motor, modified Beam F3 prefrontal, THREE-D prefrontal, orbitofrontal, and medial prefrontal) and stimulation parameters (single pulse, 10 Hz, theta burst). The secondary objective is to evaluate the knee as a surrogate location to safely trial tolerability of novel TMS parameters.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Florida State University, Tallahassee, Florida
Conditions: Healthy
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A Study of LY3437943 in Participants With Impaired and Normal Liver Function
NCT05916560
Recruiting
The main purpose of this study is to measure how much of LY3437943 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to healthy participants with normal liver function. The safety and tolerability of LY3437943 will also be evaluated. The study may last up to 9 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/25/2024
Locations: Accel Research Sites- Clinical Research Unit, DeLand, Florida +1 locations
Conditions: Healthy, Hepatic Insufficiency
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Brain Changes in Psoriasis After Secukinumab Treatment
NCT04717466
Recruiting
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception of well-being, itch, and pain in participants with psoriasis.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2024
Locations: University of Miami, Miami, Florida
Conditions: Psoriasis, Healthy
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Study of the Safety and Immune Response of an Investigational mRNA Vaccine for the Prevention of Respiratory Syncytial Virus and/or Human Metapneumovirus in Participants Aged 18 to 49 Years and 60 Years and Older
NCT06237296
Recruiting
The purpose of this study is to evaluate the safety and immunogenicity an investigational messenger ribonucleic acid (mRN)A vaccine for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) and/or human metapneumovirus (hMPV) in older adults. A single intramuscular (IM) injection of 3 to 4 different doses of the RSV/hMPV mRNA vaccine candidate formulated with 2 different lipid nanoparticles (LNP) will be administered to healthy participants aged 18... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: Velocity Clinical Research-Hallandale Beach Site Number : 8400013, Hallandale Beach, Florida
Conditions: Respiratory Syncytial Virus Infection, Healthy Volunteers, Metapneumovirus Infection
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Integrated Cancer Repository for Cancer Research
NCT02012699
Recruiting
The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant percentage of small and rural hospitals and cancer centers. The iCaRe2 advances comprehensive studies of risk factors of cancer... Read More
Gender:
All
Ages:
Between 19 years and 110 years
Trial Updated:
02/29/2024
Locations: Florida Hospital Memorial Medical Center, Daytona Beach, Florida +4 locations
Conditions: Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer, Thymus Cancer, Colon Cancer, Rectal Cancer, Anal Cancer, Bile Duct Cancer, Duodenal Cancer, Gallbladder Cancer, Gastric Cancer, Liver Cancer, Small Intestine Cancer, Peritoneal Surface Malignancies, Familial Adenomatous Polyposis, Lynch Syndrome, Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Testicular Cancer, Ureter Cancer, Urethral Cancer, Hypopharyngeal Cancer, Laryngeal Cancer, Lip Cancer, Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Paranasal Sinus Cancer, Nasal Cavity Cancer, Salivary Gland Cancer, Skin Cancer, Mesothelioma, Breast Cancer, Leukemia, Melanoma, Sarcoma, Unknown Primary Tumor, Multiple Myeloma, Ovarian Cancer, Endometrial Cancer, Vaginal Cancer, Neuroendocrine Tumors, Plasma Cell Dyscrasia, Healthy Control, Gastrointestinal Stromal Tumors, Central Nervous System Tumor, Central Nervous System Cancer
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Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents
NCT06128733
Recruiting
The purpose of VAN00010 study is to assess the safety and immunogenicity of the investigational pentavalent meningococcal ABCYW vaccine in adults and adolescents. The study duration will be up to 12 months for all participants.
Gender:
All
Ages:
Between 10 years and 25 years
Trial Updated:
02/20/2024
Locations: Life Arc Research Site Number : 8400094, Coral Gables, Florida +10 locations
Conditions: Meningococcal Infection, Healthy Volunteers
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A Phase 1a Study of PMN310 In Healthy Volunteers
NCT06105528
Recruiting
This first in human Phase 1a clinical trial will evaluate the safety, tolerability, and pharmacokinetics of a single IV infusion of PMN310 in healthy volunteers.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/16/2024
Locations: Clinical Pharmacology of Miami, LLC, Miami, Florida
Conditions: Healthy Participants
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Study of a Respiratory Syncytial Virus/Human Metapneumovirus Vaccine Candidate
NCT06134648
Recruiting
The purpose of this study is to assess the safety and immunogenicity of a single intramuscular (IM) injection of different doses of an respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) vaccine candidate, in adult participants aged 60 years and older. In addition, the study will evaluate the safety and immunogenicity of a booster vaccination administered 12 months after the primary vaccination in a subset of the study population.
Gender:
All
Ages:
60 years and above
Trial Updated:
02/08/2024
Locations: Suncoast Research Associates, LLC Site Number : 8400002, Miami, Florida
Conditions: Respiratory Syncytial Virus Infection, Healthy Volunteers, Human Metapneumovirus
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Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function
NCT05724693
Recruiting
To Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Bemnifosbuvir After a Single Dose
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/01/2024
Locations: Atea Study Site Orlando Clinical Research Center, Orlando, Florida
Conditions: Healthy Volunteer, Hepatic Impairment
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A Study of LY3502970 in Participants With Impaired and Normal Liver Function
NCT05882032
Recruiting
The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to participants with normal liver function. The safety and tolerability of LY3502970 will also be evaluated. The study may last up to 6 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/29/2024
Locations: Clinical Pharmacology of Miami, Miami, Florida +1 locations
Conditions: Healthy, Hepatic Insufficiency
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American Cranberries to Prevent UTIs in Susceptible Women
NCT04626362
Recruiting
The investigators pre-preliminary study showed that the urine from a portion of study participants had anti-adhesion activity. The investigators propose that UTI susceptible women can be divided into responders and non-responders depending on whether cranberry intake increase anti-adhesion activity of their urine. The overall objectives are to identify gut microbes and anti-adhesive urinary biomarkers which significantly contribute to the anti-adhesion of E. coli.
Gender:
Female
Ages:
Between 21 years and 65 years
Trial Updated:
12/01/2023
Locations: Food Science and human nutrition department at University of Florida, Gainesville, Florida
Conditions: Healthy
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A Study of TAK-279 in Adults With or Without Liver Damage
NCT05976321
Recruiting
The main aim of this study is to find out how the body processes 1 dose of TAK-279 (pharmacokinetics) in participants with liver problems compared to participants without liver problems. Other aims are to check for side effects from TAK-279 and to learn how well participants tolerate 1 dose of TAK-279. The participants will need to stay at the clinic for 11 days.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: University of Miami, Miami, Florida +1 locations
Conditions: Hepatic Impairment, Healthy Volunteers
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