The state of Florida currently has 42 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
A Study of LY3502970 in Participants With Impaired and Normal Liver Function
NCT05882032
Recruiting
The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to participants with normal liver function. The safety and tolerability of LY3502970 will also be evaluated. The study may last up to 6 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/29/2024
Locations: Clinical Pharmacology of Miami, Miami, Florida +1 locations
Conditions: Healthy, Hepatic Insufficiency
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American Cranberries to Prevent UTIs in Susceptible Women
NCT04626362
Recruiting
The investigators pre-preliminary study showed that the urine from a portion of study participants had anti-adhesion activity. The investigators propose that UTI susceptible women can be divided into responders and non-responders depending on whether cranberry intake increase anti-adhesion activity of their urine. The overall objectives are to identify gut microbes and anti-adhesive urinary biomarkers which significantly contribute to the anti-adhesion of E. coli.
Gender:
Female
Ages:
Between 21 years and 65 years
Trial Updated:
12/01/2023
Locations: Food Science and human nutrition department at University of Florida, Gainesville, Florida
Conditions: Healthy
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A Study of TAK-279 in Adults With or Without Liver Damage
NCT05976321
Recruiting
The main aim of this study is to find out how the body processes 1 dose of TAK-279 (pharmacokinetics) in participants with liver problems compared to participants without liver problems. Other aims are to check for side effects from TAK-279 and to learn how well participants tolerate 1 dose of TAK-279. The participants will need to stay at the clinic for 11 days.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: University of Miami, Miami, Florida +1 locations
Conditions: Hepatic Impairment, Healthy Volunteers
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Breathing & Blood Pressure
NCT05632406
Recruiting
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
Gender:
All
Ages:
Between 20 years and 45 years
Trial Updated:
11/07/2023
Locations: Florida State University, Tallahassee, Florida
Conditions: Healthy, Overweight and Obesity
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Tumor-Derived FGF19
NCT06068257
Recruiting
Identify and test thresholds, specificity and sensitivity for a potential cancer associated biomarker protein, FGF19, (and associated markers) for detection in human blood in the blood of breast and colorectal in cancer patients, and see if occurs at higher rates than healthy controls
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Burnett School Biomedical Sciences, Orlando, Florida
Conditions: Colorectal Cancer, Breast Cancer, Healthy
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Blood Collection for COM/BSBS
NCT06082661
Recruiting
The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS) research scientists and their research teams for testing according to their separate IRB-approved/exempted protocols. These separate IRBapproved protocols cannot be for genetic testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/08/2023
Locations: University of Central Florida, Orlando, Florida
Conditions: Healthy
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A Study to Evaluate the Effect of Food on LOXO-783 in Healthy Participants
NCT06028425
Recruiting
The main purpose of this study is to measure how much of LOXO-783 is in the bloodstream and how the body handles and eliminates LOXO-783 when administered in fasting and fed states in healthy participants. The study will also evaluate the safety and tolerability of LOXO-783. Participation could last up to 63 days including screening period.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
09/01/2023
Locations: Fortrea Clinical Research Unit, Daytona Beach, Florida
Conditions: Healthy
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A Study Investigating Lu AG06474 in Healthy Young Participants
NCT05943327
Recruiting
The purpose of this study is to investigate the safety of multiple oral doses of Lu AG06474, how well the doses are tolerated, and what the body does to the drug after administering it to healthy young participants. This study also aims to compare how the body absorbs and uses Lu AG06474 when it is given in capsule form versus when it is given as an oral solution.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
08/02/2023
Locations: Quotient Sciences Miami, Miami, Florida
Conditions: Healthy Participants
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Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome
NCT05408728
Recruiting
This study is trying to determine whether the success of bariatric surgery can be predicted by evaluating the dietary sugar absorptive characteristics in the small intestine and if there is any gene expression change on the dietary sugar absorptive characteristics.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Obese, Healthy, Bariatric Surgery Candidate
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Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
NCT00785525
Recruiting
The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in normal dono... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
07/21/2023
Locations: Gift of Life Bone Marrow Foundation, Boca Raton, Florida
Conditions: Healthy
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Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults
NCT04593784
Recruiting
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ciraparantag for reversal of anticoagulation induced by different anticoagulant drugs in generally healthy adults as measured primarily by an automated coagulometer device.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
07/18/2023
Locations: Qps-Mra, Llc., South Miami, Florida
Conditions: Healthy
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A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
NCT05901714
Recruiting
This study will consist of 2 parts. The study will evaluate whether administration of phenytoin impacts the single-dose drug levels of afimetoran and BMT-271199 (Part 1) and will evaluate whether multiple administrations of afimetoran impact the drug levels of midazolam and 1-hydroxymidazolam (Part 2).
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
07/12/2023
Locations: Syneos Health Clinical Research Services, Llc, Miami, Florida
Conditions: Healthy Participants
Register for Updates