There are currently 563 clinical trials in Gainesville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Florida /ID# 144834, University of Florida Health Science Center - Gainesville, University of Florida Shands Cancer Center and Sarkis Clinical Trials. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
NCT05277025
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
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Multi-center Evaluation of the Clinical Utility of ESD in the Western Population
NCT02989818
Recruiting
The aim of this multi-center study is to prospectively document the clinical utility of ESD.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Endoscopic Submucosal Dissection
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Analysis of CA-MRSA Transmission: An ED Population Sampling Strategy
NCT02363166
Recruiting
Given that the Emergency Department (ED) has become the entry way for large populations of patients into the health care system, a strategy of sampling MRSA isolates in ED populations and merging this information with patient-level data may present a window to hypothesize and investigate CA-MRSA transmission within the community and its impact on hospital-acquired infections.
Gender:
All
Ages:
1 month and above
Trial Updated:
06/09/2023
Locations: UF Health, Gainesville, Florida
Conditions: Methicillin-Resistant Staphylococcus Aureus
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Obesity and Uric Acid Stones Study
NCT04621929
Recruiting
The investigator proposes an 18 month, feasibility pilot study, randomizing obese and diabetic individuals with pure uric acid nephrolithiasis (UAN) or mixed calcium oxalate (CO) UAN to either phentermine/topiramate or a pragmatic control group who will remain on their standard medication regimen (citrate salts, allopurinol, diet, etc.).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Obesity, Uric Acid Stones, Type 2 Diabetes Mellitus in Obese, Pre-Diabetes
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Home Operations Utilizing Stimulation
NCT04484285
Recruiting
This project will utilize a home-operated stimulator in 1) a healthy young adult population and 2) a healthy older adult population to provide a proof of concept of home-use of transcutaneous vagal nerve stimulation (tVNS). tVNS is believed to modulate cognitive performance.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/09/2023
Locations: University of Florida McKnight Brain Institute, Gainesville, Florida
Conditions: Cognitive Performance
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The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Kidney Transplant Rejection
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Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
NCT05415761
Recruiting
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/07/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Tobacco Use Cessation
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To Determine the Activity and Mechanisms of Cranberries to Attenuate Skin Photoaging and Improve Skin Health in Women
NCT04183920
Recruiting
Previous studies have shown that cranberry phytochemicals scavenge reactive carbonyls. Cranberry polyphenols have been reported to attenuate collagen degradation and inhibit oxidative stress in human cells. We hypothesize that cranberry juice consumption will attenuate skin photoaging and improve skin health in women via alleviate oxidative stress.
Gender:
Female
Ages:
Between 21 years and 65 years
Trial Updated:
06/05/2023
Locations: Food Science and human nutrition department at University of Florida, Gainesville, Florida
Conditions: Skin Health
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Prospective Randomized Blinded Trial of VersaWrap Tendon Protector for Zone 2 Flexor Tendon Injuries
NCT04322370
Recruiting
To analyze outcomes between patients with Z2FT injuries following repair, randomized to two groups. The first group will be the negative control, with no tendon wrap. The second group will have a VersaWrap Tendon Protector applied over the site of the tendon repair. VersaWrap is current SOC at UF.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/05/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Flexor Tendon
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The Less is More Study
NCT05153811
Recruiting
In this project, the investigators will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use reduction among people living with HIV (PLWH). The investigators' approach to extending CM will use mobile health (mHealth) tools including a smartphone breathalyzer device with accompanying app and a wrist worn alcohol biosensor. Participants will be engaged in mobile facilitated CM for 30-60 days with follow-up out to 6 months.
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
06/05/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Alcohol Use
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Pervasive Sensing and AI in Intelligent ICU
NCT05127265
Recruiting
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all. Consequently, these important visual cues, although associated with critical indices such as physical functioning, pain, delirious state, and impending clinical deterioration, often cannot be incorporated into clinical status. The overall objectives of this project are to s... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/04/2023
Locations: University of Florida Health Shands Hospital, Gainesville, Florida
Conditions: Critical Illness, Pain, Delirium, Confusion
Register for Updates
Integrating Data, Algorithms and Clinical Reasoning for Surgical Risk Assessment
NCT02741986
Recruiting
Brief Summary: The goal of this study is to implement and test an intelligent perioperative system (IPS) that in real-time predicts risk for postoperative complications using routine clinical data collected in electronic health records. The accuracy of computer-generated risk scores will be compared to physician's risk scores for the same patients. Physicians will be also asked to provide the opinion regarding the computer-generated risk scores using interactive interface with the program. The i... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/04/2023
Locations: UF Health, Gainesville, Florida
Conditions: Postoperative Complications
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