There are currently 563 clinical trials in Gainesville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Florida /ID# 144834, University of Florida Health Science Center - Gainesville, University of Florida Shands Cancer Center and Sarkis Clinical Trials. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
NCT02216500
Recruiting
Approximately a fourth of children with seizures do not respond adequately to available therapy. Ketogenic therapy has a long history as treatment for intractable epilepsy, but there is no agreement concerning how it works and what is the best way to administer it. This natural history study will collect data pertaining to both questions.
Gender:
All
Ages:
50 years and below
Trial Updated:
12/19/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Seizures
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Electrical Inhibition of Human Preterm Contractions
NCT02983240
Recruiting
The purpose of this study is to explore a new method to stop preterm uterine contractions using an electrical device. The device, an "electrical pacemaker for the uterus," has been approved by the Food and Drug Administration (FDA) for clinical research in pregnant women. The purpose of this study is to evaluate the feasibility and safety of the device. The investigators hypothesize that human preterm uterine contractions can be safely and objectively inhibited with a weak electrical current pro... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
12/08/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Preterm Labor, PreTerm Birth, Preterm Labor With Delivery Nos
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Preventing Alzheimer's With Cognitive Training
NCT03848312
Recruiting
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residentia... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/21/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
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Thumb Osteoarthritis Mechanisms
NCT04104477
Recruiting
This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and quantitative pain testing. Completion of this study will provide a comprehensive dataset describing how movement strategies (muscle activity and joint posture) as well as experimental and clinical pain differ between individuals with CMC OA and age-matched controls.
Gender:
Female
Ages:
Between 40 years and 90 years
Trial Updated:
11/21/2022
Locations: UF Health of University of Florida, Gainesville, Florida
Conditions: Carpometacarpal Osteoarthritis
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Revitalize Cognition: Near Infrared Stimulation in Older Adults
NCT02582593
Recruiting
Changes in mood and cognition are common in older adulthood. Some studies have suggested that transcranial application of near-infrared (NIR) light may have enhancing effects on cognitive and mood status in young adults and individuals with traumatic brain injury. This effect has not been examined in older adults. This study will involve a randomized sham-controlled trial to learn whether NIR stimulation improves cognition and mood in older adults, relative to sham treated controls.
Gender:
All
Ages:
Between 62 years and 99 years
Trial Updated:
10/25/2022
Locations: The Center for Movement Disorders and Neurorestoration, Gainesville, Florida +1 locations
Conditions: Aging
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Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
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Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
NCT03926624
Recruiting
Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting period per 28-day cycles. Control arm: Non-Intensive Reinduction (LoDAC, Azacitidine, Decitabine, Venetoclax Combination Regimens) or Intensive Reinduction (High and Intermediate Dose Cytarabine Regimens), dependin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/18/2022
Locations: UF-Health Cancer Center Gainesville, Gainesville, Florida
Conditions: Leukemia, Myeloid, Acute
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Surveillance AFter Extremity Tumor surgerY
NCT03944798
Recruiting
Following treatment for a primary extremity sarcoma, patients remain at risk for the development of local and systemic disease recurrence. Metastasis (distant recurrence) to the lung is the most frequent single location of disease recurrence in sarcoma patients, occurring in almost half of all patients. Therefore, careful post-operative surveillance is an integral element of patient care. However, the detection of metastases does not necessarily affect long-term survival and may negatively impac... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/04/2022
Locations: University of Florida Health Shands Hospital, Gainesville, Florida
Conditions: Soft Tissue Sarcoma, Lung Metastases
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Long Term Cognitive Impact of Pediatric Acute Renal Injury
NCT02372734
Recruiting
The research study will investigate the longitudinal cognitive outcomes in subjects admitted as children diagnosed with sepsis who may have had acute kidney injury. Each subject will be contacted 2-15 years after their incident admission in order to solicit responses to a functional and cognitive quality of life survey. Children admitted during the same time frame that did not have kidney injury will also be surveyed.
Gender:
All
Ages:
Between 2 years and 36 years
Trial Updated:
09/14/2022
Locations: UF Health, Gainesville, Florida
Conditions: Acute Kidney Injury
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Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study
NCT05490212
Recruiting
The aim of this study is to develop a faster, safer, and more accurate method for determining if a newborn has an infection. This study involves analyzing saliva for markers of infection and inflammation known as cytokines. We will analyze infant's saliva repeatedly for inflammatory biomarkers (cytokines) within the first 36 hours of their standard of care treatment. We hypothesize that levels of these cytokines will more quickly predict which babies are truly infected and which babies are not c... Read More
Gender:
All
Ages:
All
Trial Updated:
08/04/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Infection; Newborn
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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
All
Ages:
All
Trial Updated:
07/28/2022
Locations: University of Florida, Gainesville, Florida
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
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A Sociolinguistic-enabled Web Application to Develop Precision Health Intervention for African Americans
NCT04705363
Recruiting
This pilot study will explore the preliminary efficacy of a colorectal cancer (CRC) screening intervention delivered by virtual health assistants (VHAs). Participants will include 750 African American patients in the US between the ages of 45 and 75 recruited through Qualtrics panels. The main research question is: How does the integration of different levels of dialect density of the linguistic features of African American English (AAE) influence the perceived credibility of a Black VHA. Four t... Read More
Gender:
All
Ages:
Between 45 years and 75 years
Trial Updated:
07/21/2022
Locations: Qualtrics, Gainesville, Florida
Conditions: Colorectal Cancer
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