There are currently 852 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Alternate Doses and Dosing Schedules of Belantamab Mafodotin for Treatment of Triple-Class Refractory Multiple Myeloma
NCT05847569
Recruiting
This phase II trial tests alternate doses and dosing schedules of belantamab mafodotin in treating patients with triple-class multiple myeloma that has come back (after a period of improvement) (recurrent) and/or does not respond to treatment (or that has not responded to previous treatment) (refractory). Belantamab mafodotin is a monoclonal antibody, belantamab, linked to a chemotherapy drug, mafodotin. Belantamab is a form of targeted therapy because it attaches to specific molecules (receptor... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Recurrent Multiple Myeloma, Refractory Multiple Myeloma
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A Study of Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA)
NCT05569759
Recruiting
This is a Phase 2a, multi-center, placebo-controlled study in which patients with autoimmune hepatitis will receive zetomipzomib or placebo in addition to standard-of-care for 24 weeks; an optional open-label extension period allows patients to receive zetomipzomib (KZR-616) for an additional 24 weeks of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Autoimmune Hepatitis
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Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System
NCT06157567
Recruiting
This is a non-randomized, multi-center, open-label clinical trial evaluating clinical feasibility treatments with the Profound Matrix delivery system.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
12/04/2023
Locations: Center for Morden Aesthetic Medicine, Jacksonville, Florida
Conditions: Skin Laxity, Wrinkle, Skin Condition
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Clinical Validation of the RENISCHEM L-FABP POC Assay
NCT04864847
Recruiting
This study will involve measurement of levels of a novel urinary biomarker of renal ischemia, L-FABP. The purpose of the study is to perform a clinical validation of the ability of L-FABP measurements in urine using the RENISCHEM L-FABP POC Test to predict the development of AKI within 2 days following cardiac and vascular catheterization procedures involving exposure to radiocontrast media.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: University of Florida at Jacksonville, Jacksonville, Florida
Conditions: Acute Kidney Injury, Contrast-induced Nephropathy
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Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee
NCT03940950
Recruiting
Researchers are trying to determine the safety and feasibility of autologous, adipose derived stromal vascular fraction injections in the treatment of knee osteoarthritis
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
11/30/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Osteo Arthritis Knee, Degenerative Joint Disease of Knee
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Stroke Thrombectomy and Aneurysm Registry
NCT04994756
Recruiting
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brai... Read More
Gender:
All
Ages:
Between 1 year and 120 years
Trial Updated:
11/30/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Stroke, Thromboses, Intracranial, Aneurysm, Brain
Register for Updates
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Jacksonville Center for Clinical Research, Jacksonville, Florida
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates
Florida Cerebrovascular Disease Biorepository and Genomics Center
NCT05491980
Recruiting
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by cerebrovascular disease. The information and blood samples collected may be used in future research for the study of cerebrovascular disease and to learn about, prevent or treat other health problems.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage, Aneurysmal Subarachnoid Hemorrhage, Vascular Dementia, Anoxic Brain Injury, Unruptured Intracranial Aneurysm, Carotid Artery Stenosis Symptomatic, Asymptomatic Carotid Artery Stenosis, Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage, Cerebral Venous Thrombosis, Moyamoya Disease, Fibromuscular Dysplasia, Subarachnoid Hemorrhage, Leukoaraiosis, Arteriovenous Fistula, Reversible Cerebral Vasoconstriction Syndrome, CADASIL
Register for Updates
Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT03516617
Recruiting
This phase II trials studies how well acalabrutinib with or without obinutuzumab works in treating patients with early-stage chronic lymphocytic leukemia or small lymphocytic lymphoma. Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as obinutuzumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known wh... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Register for Updates
APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
NCT03537482
Recruiting
This is a multi-center, single-agent, open-label, Phase I study of APG-2575. The study consists of the dose escalation stage and the dose expansion stage.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Hematologic Malignancies
Register for Updates
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
NCT05116943
Recruiting
The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotrophic Lateral Sclerosis (ALS) patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis
Register for Updates
Adenosine 2A Receptor Antagonism and AIH in ALS
NCT05377424
Recruiting
The purpose of this research study is to determine the effects of a medication, istradefylline, in conjunction with breathing air with reduced oxygen for short periods of time (called acute intermittent hypoxia, or AIH), on breathing. This project will study breathing in people with amyotrophic lateral sclerosis (ALS) and unaffected, age-matched adults. Istradefylline is prescribed to increase movement in people with other neuromuscular conditions. A recently completed study found that people wi... Read More
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
11/20/2023
Locations: UF Health Jacksonville, Jacksonville, Florida
Conditions: ALS
Register for Updates