There are currently 852 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Prospective Research Rare Kidney Stones (ProRKS)
NCT02780297
Recruiting
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of ren... Read More
Gender:
All
Ages:
All
Trial Updated:
11/20/2023
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Hyperoxaluria, Cystinuria, Dent Disease, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency
Register for Updates
Connect® Lymphoma Disease Registry: A US-Based Prospective Observational Cohort Study
NCT04982471
Recruiting
The Connect® Lymphoma Disease Registry is a US-based, multicenter, prospective observational (non-interventional) cohort study designed to collect real-world, participant-level data longitudinally in participants diagnosed with various subtypes of non-Hodgkin lymphoma (NHL).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: University of Florida College of Medicine Jacksonville, Jacksonville, Florida +1 locations
Conditions: Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Follicular
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Analysis of Letrozole in Patients With Operable Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT05447910
Recruiting
This phase II trial examines letrozole in patients with newly diagnosed hormone receptor-positive HER2-negative invasive breast cancer that can be removed by surgery (operable). Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Adenocarcinoma, Invasive Breast Carcinoma, Resectable Breast Carcinoma
Register for Updates
Customized TULSA-PRO Ablation Registry
NCT05001477
Recruiting
This patient registry will capture data from patients who have been or who are undergoing the transurethral ultrasound ablation (TULSA) procedure as part of their routine clinical care. The registry will shed light on real-world outcomes of safety and efficacy of the procedure and understand how a patient's quality of life is affected throughout their follow-up and lifetime.
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Prostate Cancer, Prostate Adenocarcinoma, Benign Prostatic Hyperplasia
Register for Updates
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
NCT05137665
Recruiting
Brief Summary: The goal of the study is to generate a biorepository of longitudinal blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we will enroll 200 Amyotrophic Lateral Sclerosis (ALS) patients and 80 healthy controls from multiple sites, over a 5 year time frame. Additionally, speech measures will be collected on weekly basis at home for all pa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis, Movement Disorders, Degenerative Disorder, Motor Neuron Disease
Register for Updates
Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women
NCT01310023
Recruiting
SMARTT will estimate the incidence of conditions and diagnoses potentially related to in utero exposure to antiretroviral therapy and/or exposure in the first two months of life among children born of HIV-infected mothers.
Gender:
All
Ages:
All
Trial Updated:
11/09/2023
Locations: University of Florida Health Science Center, Jacksonville, Florida
Conditions: Antiretroviral Toxicity
Register for Updates
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
NCT02932618
Recruiting
The main aim of the study is to check effectiveness, side effects, and tolerability of recombinant von Willebrand Factor (rVWF), with or without ADVATE, in the treatment and control of nonsurgical bleeding events in pediatric participants (less than (<)18 years of age) with severe hereditary von Willebrand disease (VWD). The participants will be treated with rVWF for 12-18 months. Their von Willebrand Disease will be treated by their doctor according to their doctor's usual clinical practice. D... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
11/09/2023
Locations: University of Florida College of Medicine, Jacksonville, Florida
Conditions: Von Willebrand Disease
Register for Updates
Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma
NCT03960177
Recruiting
This early phase I trial studies how well glucarpidase works in reducing toxicity in patients with osteosarcoma receiving high dose methotrexate treatment. Glucarpidase may reduce the levels of methotrexate in patients' blood and lead to shorter hospitalizations and a reduction in toxicities.
Gender:
All
Ages:
25 years and above
Trial Updated:
11/06/2023
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Osteosarcoma
Register for Updates
Responses to Backward Walking Training Post-Stroke
NCT04928482
Recruiting
Approximately 15,000 Veterans are hospitalized for stroke each year with new cases costing an estimated $111 million for acute inpatient, $75 million for post-acute inpatient, and $88 million for follow-up care over 6 months post-stroke. The investigators have previously established the effectiveness of a backward walking training program to improve gait and balance in post-stroke Veterans. To best serve Veterans in this era of personalized medicine, there is a current need to determine the appr... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/02/2023
Locations: Brooks Rehabilitation, Jacksonville, Florida
Conditions: Stroke
Register for Updates
Study of RP-3500 (Camonsertib) With Niraparib or Olaparib in Advanced Solid Tumors
NCT04972110
Recruiting
The primary purpose of this study is to assess the safety and tolerability of niraparib or olaparib in combination with RP-3500 (camonsertib), in patients with eligible advanced solid tumors, determine the maximum tolerated dose (MTD) of RP-3500 (camonsertib) in combination with niraparib or olaparib, examine pharmacokinetics (PK) and assess anti-tumor activity.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2023
Locations: Participating Site #1017, Jacksonville, Florida
Conditions: Advanced Solid Tumor, Adult
Register for Updates
FT819 in Subjects With B-cell Malignancies
NCT04629729
Recruiting
This is a Phase I dose-finding study of FT819 as monotherapy and in combination with IL-2 in subjects with relapsed/refractory B-cell Lymphoma, Chronic Lymphocytic Leukemia and Precursor B-cell Acute Lymphoblastic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/01/2023
Locations: Mayo Florida, Jacksonville, Florida
Conditions: Lymphoma, B-Cell, Chronic Lymphocytic Leukemia, Precursor B-Cell Acute Lymphoblastic Leukemia
Register for Updates
Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma
NCT03961945
Recruiting
This study will evaluate if the sponge capsule device can accurately detect the presence of Barrett's Esophagus and prevalent dysplasia/adenocarcinoma detection, in a screening population, with and without chronic gastroesophageal reflux disease.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/01/2023
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Barrett Esophagus, Esophageal Adenocarcinoma
Register for Updates