Georgia is currently home to 1946 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Atlanta, Augusta, Decatur and Savannah. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
NCT03037164
Recruiting
Stage A: To evaluate the safety and efficacy of red blood cells (RBCs) prepared with the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in patients who require RBC transfusion support. Stage B: To provide early access to the INTERCEPT pathogen reduction system for RBC in regions where a substantial proportion of the population has been infected or is at risk of a transfusion-transmissible infection. The objectives and design of... Read More
Gender:
All
Ages:
4 years and above
Trial Updated:
09/11/2023
Locations: Grady Health System, Atlanta, Georgia
Conditions: Anemia
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Mindfulness in Chronic Kidney Disease
NCT04099992
Recruiting
This study will test whether mindfulness meditation (MM) improves sympathetic function in chronic kidney disease (CKD) and whether transcutaneous vagus nerve stimulation (tVNS) optimizes the sympatho-inhibitory effects of mindfulness meditation (MM) and restores autonomic balance in CKD patients.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
09/08/2023
Locations: Atlanta VA Medical Center, Atlanta, Georgia
Conditions: Chronic Kidney Diseases
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Sympatholysis in Chronic Kidney Disease
NCT02411773
Recruiting
The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and what causes an increase in blood pressure during exercise (i.e. increased adrenaline levels, or decreased ability of blood vessels to dilate).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
09/08/2023
Locations: Atlanta VA Medical Center, Decatur, Georgia
Conditions: Chronic Kidney Disease
Register for Updates
Sympathetic Overactivity in Post-traumatic Stress Disorder
NCT01627301
Recruiting
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily DGB therapy or transcutaneous vagus nerve stimulation (tVNS) therapy improves SNS activity at rest and during stress.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
09/08/2023
Locations: Atlanta VA Medical Center, Decatur, Georgia
Conditions: Post-traumatic Stress Disorder, Prehypertension
Register for Updates
CLUE: CLinical Utility Study of EsoGuard
NCT06030180
Recruiting
Utilize real-world data from the commercial use of EsoGuard testing on samples collected with EsoCheck (EC/EG) to evaluate the impact of EsoGuard results on health care provider's decision for endoscopy referral. Assess patient compliance with recommendations for upper endoscopy, and relationship of compliance to positive EsoGuard results.
Gender:
All
Ages:
Between 12 years and 99 years
Trial Updated:
09/06/2023
Locations: Savii Health, Savannah, Georgia
Conditions: Barrett Esophagus, Barretts Esophagus With Dysplasia, Esophagus Adenocarcinoma
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Immune Monitoring and Assay Development in Organ Transplant Recipients
NCT01283295
Recruiting
The purpose of this study to develop a well-characterized library of blood, biopsy tissue, and urine samples from transplant patients. Subjects without transplants will also be enrolled for comparison. Samples will be used to study the characteristics of patients undergoing transplantation that influence their response to transplant therapies and their reactions to drugs used in transplantation. This knowledge is important as it helps physicians design new drugs and tailor transplant therapies t... Read More
Gender:
All
Ages:
All
Trial Updated:
09/06/2023
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: Organ Transplantation, Transplantation Immunology
Register for Updates
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
NCT05181137
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: One Health Research Clinic Atlanta, LLC, Norcross, Georgia
Conditions: Ulcerative Colitis
Register for Updates
AltaValve Early Feasibility Study Protocol
NCT03997305
Recruiting
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: Emory University, Atlanta, Georgia
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
Register for Updates
Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
NCT05586958
Recruiting
The aim of this 6-month randomized multi-regional double-blind parallel group placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/24/2023
Locations: Vista Clinical Research, LLC, Newnan, Georgia
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
Register for Updates
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
NCT02715284
Recruiting
This is a multi-center, open-label, first-in-human Phase 1 study evaluating the anti-programmed death receptor 1 (anti-PD-1) antibody dostarlimab (also known as TSR-042) n participants with advanced solid tumors who have limited available treatment options. The study will be conducted in 2 parts with Part 1 consisting of safety evaluation, pharmacokinetics (PK), and pharmacodynamics (PDy) of escalating doses of dostarlimab. Dose escalation will be based on ascending weight-based dose levels (DLs... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: GSK Investigational Site, Atlanta, Georgia
Conditions: Neoplasms
Register for Updates
Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination
NCT02636855
Recruiting
This screening study is intended for men and women ≥ 18 to ≤ 75 years of age who have advanced solid or hematologic malignancy. The study will assess a subject's human leukocyte antigen (HLA) subtype and tumor antigen expression profile. Based on the results, it will be determined if a subject is eligible to be considered for Adaptimmune sponsored clinical trials testing the safety and efficacy of genetically changed T cells targeting specific tumor antigens. No treatment intervention will occur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: Winship Cancer Institute - Emory University, Atlanta, Georgia
Conditions: Solid and Hematological Malignancies
Register for Updates
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
NCT04182659
Recruiting
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/07/2023
Locations: VA Atlanta, Decatur, Georgia
Conditions: Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain
Register for Updates