Georgia is currently home to 1952 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Atlanta, Augusta, Decatur and Savannah. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
NCT05303636
Recruiting
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in comparison to non-hormonal contraceptive methods. Secondary objectives include further evaluating the impact of LF111 and DRSP 3.5 mg chewable tablets on BMD and bone turnover after 12 months (13 medication cycles) in comparison to non-hormonal contraceptive methods and a... Read More
Gender:
Female
Ages:
Between 14 years and 45 years
Trial Updated:
06/15/2023
Locations: M3 Wake Research, Inc., Sandy Springs, Georgia
Conditions: Change in Bone Mineral Density, Bone Loss
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Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
NCT04272996
Recruiting
This study is designed to evaluate the effectiveness of endovascular embolization of middle meningeal artery following evacuation of subdural hematomas (SDHs) to assess rate of recurrence. The historical standard for treatment of subdural hematomas has been surgical evacuation through burr holes or craniotomies. Many of these patients are elderly patients who are high risk surgical candidates. A major concern is SDH recurrence. Recurrences require frequent imaging, and will lead to increased le... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
06/14/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Chronic SDH and the Efficacy of Embolization
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TRIAD Appendicitis Decision-making Surveys
NCT05887414
Recruiting
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients w... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Grady Health System / Morehouse School of Medicine, Atlanta, Georgia
Conditions: Appendicitis
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Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
NCT05291884
Recruiting
This is a prospective, multi-center, single-arm, early feasibility study that aims to evaluate the safety of the Impella BTR™ in adult patients requiring left-ventricular hemodynamic support, and to evaluate the effectiveness of the Impella BTR™ in supporting patients to recovery or their next therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2023
Locations: Emory University Hospital, Atlanta, Georgia
Conditions: Heart Failure, Acute Decompensated Heart Failure
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AMP SCZ® Observational Study: PREDICT-DPACC
NCT05905003
Recruiting
The Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) is a large international collaboration to develop algorithms using a set of clinical and cognitive assessments, multi-modal biomarkers, and clinical endpoints that can be used to predict the trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the testing of pharmacological interventions for CHR individuals in need. The goal is to accurately predict which individuals are likely to remit,... Read More
Gender:
All
Ages:
Between 12 years and 30 years
Trial Updated:
06/06/2023
Locations: University of Georgia, Athens, Georgia
Conditions: Clinical High Risk, Psychosis, Remission, Conversion
Register for Updates
Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT01060371
Recruiting
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as Machado-Joseph disease and SCA 6). The diseases are rare, slowly progressive, cause increasingly severe neurological difficulties and are variable across and within genotypes. The purpose of this research study is to bring together a group of experts... Read More
Gender:
All
Ages:
6 years and above
Trial Updated:
05/30/2023
Locations: Emory University, Atlanta, Georgia
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
Register for Updates
Firdapse for Post-BOTOX Vocal Weakness
NCT05123053
Recruiting
Botox injections into the thyroarytenoid muscle are a predictable and effective treatment for SD, but typically result in transient symptoms of voice weakness and breathiness during the first 2-3 weeks after injection. Investigators hypothesize that voice weakness and breathiness after Botox treatment can be alleviated using amifampridine.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Vocal Weakness(Post-BOTOX Injection)
Register for Updates
International CIPN Assessment and Validation Study
NCT04633655
Recruiting
This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: Northside Hospital, Atlanta, Georgia
Conditions: Chemotherapy-induced Peripheral Neuropathy, Quality of Life
Register for Updates
Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery
NCT05881564
Recruiting
To evaluate if there is any clinical difference in patients 3.5-12kg who undergo cardiac surgery with cardiopulmonary bypass that do and do not receive blood products as part of their procedure. The main hypothesis of the study is that the patients undergoing bloodless cardiac surgery will have decreased morbidity and mortality when compared to the cohort that did receive blood as well as a shorter ICU and hospital length of stay.
Gender:
All
Ages:
All
Trial Updated:
05/19/2023
Locations: Children's Hospital of Georgia, Augusta, Georgia
Conditions: Congenital Heart Disease
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RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) Without Center Involved-Diabetic Macular Edema (CI-DME)
NCT04567550
Recruiting
RGX-314 is being developed as a novel, potential one-time gene therapy treatment for the treatment of diabetic retinopathy, a chronic and progressive complication of diabetes mellitus. Diabetic retinopathy (DR) is a sight-threatening disease characterized in the early stages by neuronal and vascular dysfunction in the retina, and later by neovascularization that leads to further deterioration of functional vision. Despite the availability of current treatments, diabetic retinopathy remains the l... Read More
Gender:
All
Ages:
Between 25 years and 89 years
Trial Updated:
05/18/2023
Locations: Southeast Retina Center, PC, Augusta, Georgia
Conditions: Diabetic Retinopathy (DR)
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A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
NCT05866861
Recruiting
The main purpose of this study is to evaluate the safety and tolerability of CUG252 following multiple ascending doses in participants with Systemic Lupus Erythematosus (SLE).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: Site 1007, Lawrenceville, Georgia
Conditions: Systemic Lupus Erythematosus, SLE (Systemic Lupus), Autoimmune
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COVID-19 Outcome Prediction Algorithm
NCT05471011
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Atlanta VA Medical Center, Decatur, Georgia
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
Register for Updates