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Kentucky Paid Clinical Trials
A listing of 1014 clinical trials in Kentucky actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Kentucky is currently home to 1014 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Louisville, Lexington, Owensboro and Paducah. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Featured Trial
Gout Clinical Research Study
Recruiting
Struggling to manage gout flares? Are you familiar with the side effects of urate lowering treatments? You may be able to help our clinical study develop safer and more effective medicines to reduce uric acid and ease inflammation.
Eligible participants will receive study-related medical care at no cost.
Eligible participants will receive study-related medical care at no cost.
Conditions:
Gout
Gout Flare
Acute Gout
Chronic Gout
Gout Attack
Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
Recruiting
The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
08/19/2022
Locations: Springs Medical Center, Louisville, Kentucky
Conditions: Interstitial Cystitis
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy.
Condition or disease:
Breast Cancer
Intervention/treatment:
Drug: Gedatolisib
Drug: Palbociclib
Drug: Fulvestrant
Drug: Alpelisib
Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: University of Kentucky Medical Center, Lexington, Kentucky
Conditions: Breast Cancer
Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer
Recruiting
Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer
Phase Ib (China only):
Approximately 90 patients
Phase Ⅱ (globally):
Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/28/2022
Locations: Norton Cancer Institute, Louisville, Kentucky
Conditions: C-Met Exon 14 Mutation
Treatment Study of AV Node Reentry Tachycardia
Recruiting
Compare the effectiveness and safety of two techniques for modification of slow AV nodal pathway conduction underlying AVNRT: 1) New Ablation Technique, low voltage and wave front collision mapping vs. 2) the Standard Ablation Technique, an anatomical/electrogram approach.
Gender:
All
Ages:
21 years and below
Trial Updated:
07/26/2022
Locations: University of Louisville, Louisville, Kentucky
Conditions: Supraventricular Tachycardia
A Phase 1b Study of a Q-Griffithsin Intranasal Spray for Broad-spectrum Coronavirus Prophylaxis
Recruiting
The purpose of this study is to test the safety of multiple doses of a Q-GRFT nasal spray in healthy volunteers. This Q-GRFT nasal spray is "investigational and not approved by the FDA for general use" and is being developed to prevent the transmission of COVID-19 and other coronaviruses.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/27/2022
Locations: University of Louisville Clinical Trials Unit, Louisville, Kentucky
Conditions: COVID-19 Prevention
CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Delivery System at Three Nicotine Concentrations in an Ambulatory Setting
Recruiting
This is a multi-center, open-label, parallel, three-study-group investigation to evaluate the puffing patterns of healthy adult consumers of tobacco products switching from a usual brand (UB) Electronic Nicotine Delivery Systems (ENDS) product to the ENDS Investigational Product (IP), over a 9-day ambulatory period.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/23/2022
Locations: AMR Lexington, Lexington, Kentucky
Conditions: Smoking, Tobacco Use, Electronic Cigarette Use
A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata
Recruiting
Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2022
Locations: Site 10-116, Louisville, Kentucky
Conditions: Alopecia Areata
The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors
Recruiting
The microbiome has the potential to serve as a robust biomarker of clinical response to immunotherapy. Additionally, microbial manipulation, through diet, exercise, prebiotics, probiotics, or microbially-derived metabolites, may prove to be beneficial in promoting anti-tumor immune responses. However, large prospective studies in humans with longitudinal sample collection and standardized methods are needed to understand how microbiota and their byproducts affect cancer therapies, particularly a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2022
Locations: Baptist Health Clinical Research, Elizabethtown, Kentucky
Conditions: Non-Small-Cell Lung Carcinoma, Malignant Melanoma, Renal Cell Carcinoma, Triple-Negative Breast Cancer
NSAIDS vs Opioids in Tibial Fractures
Recruiting
This study will attempt to determine if there is a statistic difference between the time to union, non-union rate and post-operative pain of patients who receive opioids for pain control vs. patients who receive NSAIDs and a reduced dosage of opioids for pain management
Gender:
All
Ages:
Between 18 years and 105 years
Trial Updated:
04/15/2022
Locations: University of Louisville Hospital, Louisville, Kentucky
Conditions: Trauma
Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring
Recruiting
This research study proposes to determine how well tolerated and effective lower and upper oral dental devices are at reducing snoring. The device is designed to move the genioglossus muscle forward, with interior attachment to maintain forward placement of of he tongue on the bottom of the mouth.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/05/2022
Locations: Norton Clinical Research Group, Louisville, Kentucky
Conditions: Snoring
PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies
Recruiting
Product: PSB202 is a novel biological entity consisting of two engineered monoclonal antibodies, an Fc-enhanced humanized type II anti-CD20 IgG1 (PSB102) and a humanized anti-CD37 IgG1 (PSB107), that target B-cells. PSB202 is manufactured to work as a single product with the two components of PSB202 enabling a distinct dual target-specific antibody directed cell killing of B-cells.
Study: Multi-center-, International Phase 1a/1b (Escalation/Expansion) study in patients with indolent-, relapsed-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2022
Locations: Norton Cancer Institute, Louisville, Kentucky
Conditions: Follicular Lymphoma, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia, Marginal Zone Lymphoma, Mantle Cell Lymphoma, Indolent Lymphoma, Refractory B-Cell Lymphoma, MALT Lymphoma
Home OCT Fluid Visualization Agreement Study
Recruiting
This is a single arm study of home monitoring with the NVHO for 5 weeks with office visits at enrollment, Week 1 and Week 5 (Exit Visit) and, when applicable, Interim Visit(s) triggered by ongoing review by the Reading Center. The study will enroll subjects diagnosed with NV-AMD in at least one eye with attention to the proportion of eyes with IRF and/or SRF. The enrolled eligible subjects will be instructed to self-image the study eye(s) once daily for 5 weeks using a NVHO device at home with s... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
03/08/2022
Locations: Retina Associates of Kentucky, Lexington, Kentucky
Conditions: Neovascular Age-related Macular Degeneration