There are currently 2781 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Beth Israel Deaconess Medical Center and Brigham and Women's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
NCT05724173
Recruiting
The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/30/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked in Syndrome, Muscular Dystrophies
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Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement
NCT02810704
Recruiting
PEPPER is a randomized study comparing the three most commonly used anticoagulants in North America in patients who have elected to undergo primary or revision hip or knee joint replacement surgery. The anticoagulants being compared are enteric coated aspirin, low intensity warfarin, and rivaroxaban.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/30/2023
Locations: Brigham & Women's Hospital, Boston, Massachusetts +2 locations
Conditions: Pulmonary Embolism, Venous Thrombosis
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Financial Incentives for Homeless Smokers: A Community-based RCT
NCT04445662
Recruiting
This community-based randomized controlled trial will test the effect of contingent financial rewards on smoking abstinence among homeless-experienced adult cigarette smokers. Participants will be recruited from 3 Boston Health Care for the Homeless Program locations: a shelter clinic, a day center clinic, and a medical center clinic. All participants will be offered a varenicline prescription and tobacco coaching. Incentive arm participants will receive escalating financial rewards for saliva c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/30/2023
Locations: Boston Health Care for the Homeless Program, Boston, Massachusetts
Conditions: Tobacco Smoking
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Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
NCT06038318
Recruiting
The goal of this study is to find the best way to help participants and families manage the stress of facing a serious illness and be better able to "bounce back" or be resilient after a difficult situation. Participants will take part in the "Promoting Resilience in Stress Management" PRISM program, which is designed to provide skills to change or improve the impact of stress in everyday life. The name of the intervention used in this research study is: -PRISM (a mobile app program comprised... Read More
Gender:
All
Ages:
Between 12 years and 25 years
Trial Updated:
10/30/2023
Locations: Boston Children's Hospital, Boston, Massachusetts +1 locations
Conditions: Stress, Anxiety
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The Effects of Dupilumab on Allergic Contact Dermatitis
NCT03935971
Recruiting
The aim of this study is to investigate the effects of dupilumab on allergic contact dermatitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/29/2023
Locations: Brigham and Women's Hospital, Department of Dermatology, Boston, Massachusetts
Conditions: Allergic Contact Dermatitis
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Stroke Motor Rehabilitation and Recovery Study
NCT03485040
Recruiting
SMaHRT (Stroke Motor reHabiliation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic and hemorrhagic stroke.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
10/29/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Stroke, Ischemic
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Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors
NCT04446351
Recruiting
This first-time-in-human (FTIH) study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of escalating doses of GSK6097608 given as monotherapy and in combination with dostarlimab in participants with advanced solid tumors. In addition, dostarlimab will be given as monotherapy (Arm D); and in combination with belrestotug (Arm E); and with GSK6097608 + belrestotug (Arm F) in Japanese and Chinese participants. The study may asses... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/29/2023
Locations: GSK Investigational Site, Boston, Massachusetts
Conditions: Neoplasms
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Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
NCT04039464
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
All
Ages:
Between 3 months and 18 years
Trial Updated:
10/27/2023
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Pediatric Pulmonary Hypertension
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An Ethical Approach to Detecting Covert Consciousness
NCT05010265
Recruiting
This study aims to develop an ethical approach to developing and deploying novel neurotechnologies to aid in the detection of consciousness and prediction of recovery after brain injury.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Disorder of Consciousness
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INTREPId (INTermediate Risk Erection PreservatIon Trial)
NCT04025372
Recruiting
This research study is comparing the use of a new form of hormonal therapy used with radiation as a possible treatment for intermediate risk prostate cancer. More specifically, this research would help determine whether this new form of hormonal therapy is as effective as the standard hormone therapy while also preserving erectile function.
Gender:
Male
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Beth Israel Deaconness Medical Center, Boston, Massachusetts +2 locations
Conditions: Prostate Cancer
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Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis
NCT05322070
Recruiting
A study to evaluate the safety and efficacy of YUTIQ® 0.18 mg intravitreal implant for the management of chronic non-infectious posterior segment uveitis (intraocular inflammation) that has responded to previous steroid therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Opthalmic Consultants of Boston, Boston, Massachusetts
Conditions: Uveitis, Posterior
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PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery
NCT06089083
Recruiting
This study seeks to understand how frailty, a term that describes people who are more vulnerable stressors such as a new medical problem, affects the outcomes and quality of life in adult patients with gynecologic cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/25/2023
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Malignant Female Reproductive System Neoplasm, Gynecologic Cancer, Gynecologic Neoplasm
Register for Updates