There are currently 2702 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Impact of Intensive Computerized Cognitive Training
NCT06130735
Recruiting
To investigate factors that predict cognitive enhancement following engagement in an intensive Computerized Cognitive Training Protocol.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
11/08/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Acquired Brain Injury, Mild Cognitive Impairment, Mild Neurocognitive Disorder
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Genetic Basis of Mitral Valve Prolapse
NCT01719211
Recruiting
The investigators have successfully identified two novel genetic loci for MVP on chromosomes 11 and 13 and are searching for altered genes in these regions. This requires recruiting large families who may have MVP linked to these or other chromosomes; and obtaining DNA samples from 1,000-1,500 individually affected patients to study the relation between DNA markers throughout the genome and MVP. It is our expectation that the results of this study will lead to the discovery of gene(s) responsibl... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/07/2023
Locations: Mass General Hospital, Boston, Massachusetts
Conditions: Mitral Valve Prolapse
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Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
NCT00595491
Recruiting
Asthma is a heterogeneous disorder in which multiple potential inflammatory pathways contribute to airway obstruction. The biological basis for airway inflammation is the subject of intensive investigation. This work is designed to identify airway factors that are responsible for recruiting cells and associate their airway presence with atopy and asthma.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
11/03/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Asthma
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Sensor-based Characterization of Depression
NCT04370002
Recruiting
This is a longitudinal study where individual with Major Depressive Disorder (MDD) will be monitored for 12 weeks. The study aims to develop an objective, sensor-based, algorithm able to detect the presence of depression as well as predict treatment response. Measurement-based treatment is considered optimal and the development of a valid passive, objective, behavioral and biological assessment of depressive symptoms that does not rely on clinician interviews will improve monitoring and ultimate... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/02/2023
Locations: Depression Clinical Research Program, Boston, Massachusetts +1 locations
Conditions: Unipolar Depression
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A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
NCT01873131
Recruiting
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma. The investigators also want to find out if pulsed dye laser treatment and timolol maleate 0.5% gel are safe to use without causing too many side effects. Hemangioma is a common type of birthmark. These birthmarks happen when many new blood vessels grow in a specific area on the skin. Blood vessels are tiny tubes that carry blood through the body. No one know... Read More
Gender:
ALL
Ages:
3 months and below
Trial Updated:
11/01/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hemangioma
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Lenvatinib in Locally Advanced Invasive Thyroid Cancer
NCT04321954
Recruiting
This research is being done to evaluate the safety and efficacy of neoadjuvant lenvatinib on surgical outcomes of patients with invasive extrathyroidal differentiated thyroid cancer (DTC). This research study involves a study drug called lenvatinib
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/01/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Differentiated Thyroid Cancer, Advanced Cancer
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Effects of MIB-626 With and Without A High-Intensity Multi-Dimensional Exercise Training Program
NCT05878119
Recruiting
A single-center, randomized, placebo-controlled study in community dwelling, healthy, regularly exercising, highly physically fit men and women, 19 to 40 years. Eligible participants will be randomized to receive either 1000 mg NMN or placebo twice daily for 10 weeks.
Gender:
ALL
Ages:
Between 19 years and 40 years
Trial Updated:
11/01/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Healthy
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An Ethical Approach to Detecting Covert Consciousness
NCT05010265
Recruiting
This study aims to develop an ethical approach to developing and deploying novel neurotechnologies to aid in the detection of consciousness and prediction of recovery after brain injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Disorder of Consciousness
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MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction
NCT05673005
Recruiting
The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.
Gender:
ALL
Ages:
Between 40 years and 70 years
Trial Updated:
10/25/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Erectile Dysfunction Following Radical Prostatectomy
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Urologic Lymphadenectomy in AMIGO
NCT05132283
Recruiting
This research study involves the use of two navigation systems, the 3D Slicer-based navigation system, and the Siemens Monaco systems, to simplify the complexity of image-guided lymphadenectomy procedures (surgery to remove one or more lymph nodes) in patients with urological cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Urologic Cancer, Lymph Node Metastasis
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A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
NCT05899361
Recruiting
This research study is a pilot clinical trial, which hypothesizes that the combination of electromagnetic tracking in conjunction with laparoscope imaging and ultrasound probe imaging will aid in reducing the complexity of both laparoscopic lymphadenectomy and/or organ removal in patients with a confirmed diagnosis of cancer in urologic regions of interest (Bladder, Prostate, Testicular, Kidney, Urethral, and Penis), by resulting in better visualization and more accurate localization of certain... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Urologic Cancer, Urologic Neoplasms, Bladder Cancer, Prostate Cancer, Testicular Cancer, Kidney Cancer, Urethral Cancer, Penile Cancer
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Triage Survey for Neurology Research Eligibility
NCT06104852
Recruiting
TRIAGE-Neuro is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored neurology clinical trials.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Copley Clinical, Boston, Massachusetts
Conditions: Alzheimer Disease
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