There are currently 1342 clinical trials in Columbus, Ohio looking for participants to engage in research studies. Trials are conducted at various facilities, including Nationwide Children's Hospital, Ohio State University Comprehensive Cancer Center, Ohio State University and The Ohio State University. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Risk of Chemotherapy Toxicity in Older Patients With Blood Cancer or Non-small Cell Lung Cancer
NCT05106374
Recruiting
This trial evaluates the risk of chemotherapy toxicity in older patients with blood cancer or non-small cell lung cancer. The purpose of this study is to describe a patient's wellness before and after chemotherapy treatment. This may help researchers better understand patient's ability to tolerate treatment and in the future devise the best treatment for a patient based on their "fitness."
Gender:
All
Ages:
60 years and above
Trial Updated:
11/14/2021
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Lung Non-Small Cell Carcinoma
Register for Updates
Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery
NCT04007094
Recruiting
This is a prospective, single-arm post market study of patients to assess fusion in one or multiple continuous levels of the lumbosacral spine (L1-S1) using ViviGen Cellular Bone Matrix. All subjects will be followed out to 24 months for final assessment.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2021
Locations: Ohio State University, Columbus, Ohio
Conditions: Degenerative Disc Disease, Spinal Stenosis, Spondylosis, Spondylolisthesis
Register for Updates
Stomach Intestinal Pylorus-Sparing Bariatric Surgery
NCT05094830
Recruiting
This study will evaluate the safety and efficacy of Stomach Intestinal Pylorus Sparing (SIPS) as a primary bariatric surgery. In addition, we will evaluate the safety and efficacy of SIPS performed as a revisional surgery following sleeve gastrectomy (SG) in which adequate weight loss was not achieved.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
10/15/2021
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Obesity
Register for Updates
Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: Ohio State University College of Medicine, Columbus, Ohio
Conditions: Relapsed Refractory Multiple Myeloma
Register for Updates
Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Aventiv Research, inc., Columbus, Ohio
Conditions: Female Sexual Arousal Disorder
Register for Updates
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
NCT04625686
Recruiting
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for suicidal adolescents in target population. To achieve this goal, the investigators propose a multi- site study to compare telehealth, OCIC, and inpatient care, and see which can lead to a lower risk of a suicidal event (primary outcome) as well as higher treatment satisfaction... Read More
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
04/26/2021
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Suicidal Ideation
Register for Updates
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies, the PROCEED Study
NCT04753255
Recruiting
This study gathers information on patients at different stages of chronic pancreatitis to better understand the natural course and risk factors associated with pancreatitis. Chronic pancreatitis is a disease that occurs when the pancreas is inflamed (swollen and irritated) all of the time. It is important for doctors to diagnose chronic pancreatitis in the beginning stages of the disease. Over time, as chronic pancreatitis gets worse, the pancreas may stop working correctly. Since treatment opti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/22/2021
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Acute Pancreatitis, Chronic Pancreatitis
Register for Updates
The Impact of Human Milk Oligosaccharide 2'-Fucosyllactose
NCT04718662
Recruiting
This is a double blinded, randomized, controlled trial of 2'-Fucosyllactose in infants born between 29 and 32 weeks gestational age. The investigators anticipate enrollment of 90 subjects in total and for the study to be completed in 18 months. The investigators anticipate collecting clinical data, anthropometrics, stool samples (requiring appropriate storage through analysis), salivary samples from mother and infant, discarded blood samples from baby after the standard care lab tests are done,... Read More
Gender:
All
Ages:
10 days and below
Trial Updated:
01/19/2021
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Premature Birth
Register for Updates
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
NCT04519099
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: OSU Psychiatry Department, Columbus, Ohio
Conditions: Schizophrenia
Register for Updates
REtroperitoneal SArcoma Registry: an International Prospective Initiative
NCT03838718
Recruiting
Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma (RPS). Available studies regarding oncologic outcomes are mainly retrospective in nature, and RPS are recognized as a rare disease. Therefore, prospective analysis of high quality data is a top priority. Primary Objectives of this study are: to prospectively collect standardized clinical data and radiological and pathological material from primary RPS patients treated with surgery at ref... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/11/2019
Locations: The Ohio State University, Columbus, Ohio
Conditions: Retroperitoneal Sarcoma
Register for Updates