Oregon Clinical Trials

A listing of Oregon Clinical Trials actively recruiting patient volunteers.

Perhaps best known to generations of children for the Oregon Trail, a nearly 2,200-mile wagon route from Missouri to Oregon, the trail's terminus of Oregon City remains one of the state's largest cities today. Its capital is Salem, while its other big cities include Portland and Eugene. The state borders the Pacific Ocean, while the Columbia River forms its northern border with Washington. These days it is increasingly staking out a reputation as a regional leader on the healthcare front. The 552-bed Providence St. Vincent Medical Center in Beaverton, OR is the state's largest largest facility for acute patient care.

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1297 trials found

Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)


The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.

Conditions: Multiple Myeloma

Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy


The purpose of the study is to evaluate the safety of Rifaximin or placebo in subjects with severe hepatic impairment and Hepatic Encephalopathy.

Conditions: Hepatic Encephalopathy

Acute Management of Humeral Shaft Fractures: Sling vs. Splint


When people break their arm and arrive at Oregon Health and Science University's Emergency Department (OHSU ED), they are treated with a short-term means of immobilizing their broken arm. The two most common ways of stabilizing the broken parts of the arm are 1) with a plaster-based coaptation splint, or 2) with a soft cloth sling and swathe. These hold the arm steady until the patient can schedule an appointment with the OHSU Orthopaedic Trauma clinic where they will receive definitive evaluati ...

Conditions: Fracture of Shaft of Humerus
Phase: Not Applicable

Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma


This phase I/II trial studies the side effects and best dose of ipilimumab and nivolumab when given together with brentuximab vedotin, and how well they work in treating patients with Hodgkin lymphoma that has returned after a period of improvement (recurrent) or has not responded to previous treatment (refractory). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of cancer cells to ...

Conditions: Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma
Phase: Phase 1/2

Relaxin in Multiple Sclerosis (MS)


This study will evaluate relaxin (RLX) and Semaphorin 4A (Sema4A) levels in patients with multiple sclerosis.

Conditions: Multiple Sclerosis, Relapsing-Remitting

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry


This registry will collect data on the strategies used to achieve a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) and the treatment and management efforts applied throughout study follow-up, clinical outcome events and patient reported outcome data. Blood samples will be collected periodically throughout the study for use in future research efforts. For participants with non-IPF, chronic fibrosing ILD with progre ...

Conditions: Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Eye Pressure Lowering Surgery


The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.

Conditions: Glaucoma

Functional and Structural Imaging for Glaucoma


The specific aims of the clinical studies are to: Develop a directional high-resolution OCT and OCT angiography prototype to improve imaging of structure and perfusion. Validate wide-field OCT and OCT angiography parameters to improve early glaucoma detection. Simulate visual field results by combining structural and angiography OCT data. Assess abilities of above technologies and OCT-derived parameters on predicting glaucoma detection, conversion, and progression.

Conditions: Glaucoma

A Safety Study of SGN-LIV1A in Breast Cancer Patients


This study will examine the safety and tolerability of ladiratuzumab vedotin (LV) in patients with metastatic breast cancer. LV will be given alone or in combination with trastuzumab.

Conditions: HER2 Positive Breast Neoplasms, Hormone Receptor Positive Breast Neoplasms, Triple Negative Breast Neoplasms, HER2 Mutations Breast Neoplasms

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)


This is a multi-center, randomized, placebo-controlled, double blind clinical study to assess the efficacy and safety of two separate dose regimens of Alpha-1 MP versus placebo for 156 weeks (i.e., 3 years) using computed tomography (CT) of the lungs as the main measure of efficacy. The two Alpha-1 MP doses to be tested are 60 mg/kg and 120 mg/kg administered weekly by IV infusion for 156 weeks. The study consists of an optional pre-screening phase, Screening Phase, a 156-week Treatment Phase, a ...

Conditions: Pulmonary Emphysema in Alpha-1 PI Deficiency

Reaching Out to Distressed Medical Residents, Fellows and Faculty


The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with a clinician anonymously are hypothesized to increase willingness to come for counseling in person. Suicide risk factors are expected to be lower once the distressed medical trainee or faculty member re ...

Conditions: Depression, Suicide
Phase: Not Applicable

Optical Coherence Tomography (OCT) in Uveitis


Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer (one one-thousandths) scale imaging of biological tissue. This allows excellent assessment of the white blood and inflammatory cells seen in uveitis, an inflammation of any or all parts of the uvea (iris, ciliary body, choroid).

Conditions: Uveitis