Rhode Island is currently home to 505 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Providence, Warwick, East Providence and Johnston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Strategies for Improving Remote-based Weight Loss (PATH Trial)
NCT06166225
Recruiting
The purpose of this study is to examine whether the addition of online yoga classes, compared to health and wellness classes, can improve the amount of weight loss produced from an Internet-based weight loss program. All individuals will receive a 12-month, automated Internet-based weight loss program. Following 3 months of of weight loss treatment, individuals will be randomized to also receive yoga classes or health and wellness classes for 9 months. Assessments will occur at baseline, 3, 6, 1... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/05/2025
Locations: The Miriam Hospital's Weight Control and Diabetes Research Center, Providence, Rhode Island
Conditions: Obesity
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Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
NCT04500847
Recruiting
This is a randomized, double-blind clinical trial of a daily oral dose of 200 mg emtricitabine vs. placebo in 35 participants with biomarker-confirmed MCI or mild to moderate dementia due to Alzheimer's disease. Study duration for each subject participating in the placebo-controlled research study will be approximately 12 months (up to a 3 months Screening Period, Baseline visit (1 month), 6 months of placebo or emtricitabine dosing, and 1 month follow-up). Participants will have up to 2 months... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
05/01/2025
Locations: Memory and Aging Program, Butler Hospital, Providence, Rhode Island
Conditions: Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Moderate Dementia
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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
NCT06233461
Recruiting
Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. The purpose of this study is to evaluate the efficacy and safety of TAK-279 versus placebo in participants with moderately to severely active Crohn's disease (CD). The main aim of this study is to learn if the 3 different doses of TAK-279 reduce bowel inflammation and ulcers in the bowel compared to the placebo after 12 weeks of treatment. Another aim is to compare any medical problems that... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/30/2025
Locations: University Gastroenterology Providence, Providence, Rhode Island
Conditions: Crohn's Disease
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Team Science (The Liver Health Study)
NCT06924281
Recruiting
Liver damage from alcohol intake and weight-related behaviors is preventable and treatable only through lifestyle changes. This mixed-methods randomized controlled trial compares standard and enhanced approaches to screening, brief intervention, and referral to treatment/prevention (SBIRT/P) to identify and intervene for metabolism- and alcohol-associated liver disease (MetALD). Our multidisciplinary team aims to show that integrating results of noninvasive liver screening with Fibroscan®, a pai... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/29/2025
Locations: Clinica Esperanza Hope Clinic, Providence, Rhode Island
Conditions: Steatotic Liver Disease of Mixed Origin (MetALD)
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Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
NCT05937854
Recruiting
The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs. The investigators will also assess whether tadalafil improves quality of life, home daily physical activity, exercise endurance, the frequency of acute flares of COPD, blood pressure in the lungs, and lung function. Veterans who enroll in the trial will be allocated by chance to either active tadalafil or an i... Read More
Gender:
ALL
Ages:
Between 35 years and 89 years
Trial Updated:
04/29/2025
Locations: Providence VA Medical Center, Providence, RI, Providence, Rhode Island
Conditions: Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Dyspnea
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Device Global Registry for the IlluminOss Bone Stabilization System
NCT05206981
Recruiting
This is a multi-center, observational patient registry. The primary objective of the study is to collect safety and performance data on the IlluminOss Device when used to provide stabilization and alignment for the treatment of traumatic or impending and pathologic fractures.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/28/2025
Locations: Ortho Rhode Island, Wakefield, Rhode Island
Conditions: Traumatic Fracture, Pathological Fracture
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Project REST: Regulation of Eating and Sleep Topography
NCT04057716
Recruiting
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for cardiovascular disease. Although the investigator's data suggest that disrupted or shortened sleep may be causally associated with increased energy intake and weight gain in children, and with self-regulation and neural response to food cues in adults, understanding of mechanisms... Read More
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
04/28/2025
Locations: Weight Control & Diabetes Research Center, Providence, Rhode Island
Conditions: Obesity, Childhood, Binge Eating, Sleep, Self-regulation
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C-Brace Prospective Registry
NCT04640584
Recruiting
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
Gender:
ALL
Ages:
All
Trial Updated:
04/25/2025
Locations: South County Artificial Limb and Brace, Wakefield, Rhode Island
Conditions: Pareses, Lower Extremity
Register for Updates
TECH App Marijuana Use Intervention for Court-Involved Adolescents
NCT05979272
Recruiting
The study is about helping teens who are involved in the court system to cut down or quit using marijuana. Teens may be asked to test out an experimental smartphone app, called TECH, that will be used only by teens in this study. This app is a private online community where teens can work towards changing their substance use and other behavior with the help of other anonymous teens. We will use this information to learn how the app may help teens make a change and to improve the TECH app.
Gender:
ALL
Ages:
Between 14 years and 18 years
Trial Updated:
04/24/2025
Locations: Rhode Island Family Court, Providence, Rhode Island
Conditions: Cannabis Use, Adolescent
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The Effect of a Custom Pillow on Sleep Quality in Patients With Nonoperative Rotator Cuff Syndrome
NCT05011331
Recruiting
The objective of this study is to determine if a pillow sleep aid improves sleep quality in the short term for patients who have shoulder pain from a rotator cuff injury and are being managed non-operatively.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: University Orthopedics, East Providence, Rhode Island
Conditions: Rotator Cuff Injuries
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HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain
NCT06931158
Recruiting
The goal of this clinical trial is to examine the effect of rationale condition when taking open-label placebos on pain by 1) comparing each rationale to the no rationale control condition and the no treatment control condition; and 2) comparing the rationale conditions to each other. We also aim to examine the effect of rationale condition on prescription opioid use by 1) comparing each rationale to the no rationale control condition and the no treatment control condition; and 2) comparing the... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
04/23/2025
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Chronic Low-back Pain, Chronic Pain
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Improving Physical Activity Participation in Latinas With Mindfulness
NCT06848335
Recruiting
In this study, the investigators are exploring how a mindfulness-based physical activity program can help improve exercise habits and overall health among 258 inactive Latina women aged 18 to 65. The study will be conducted entirely remotely over and 18 month period. During the first 6 months, all participants will receive an exercise program that has previously been tested by our research team. After 6 months, the investigators will check if participants are meeting the recommended exercise gui... Read More
Gender:
FEMALE
Ages:
Between 18 years and 65 years
Trial Updated:
04/23/2025
Locations: Brown University, Providence, Rhode Island
Conditions: Inactivity, Inactivity/low Levels of Exercise, Inactivity, Physical
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