Rhode Island is currently home to 486 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Providence, Warwick, East Providence and Johnston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
NCT05754190
Recruiting
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary goal of the study is to use fluctuations in daily self-reported symptoms to identify computational predictors of acute-chronic pain transition, pain recovery, and/or chronic pain maintenance or flareups. The general study will include anyone with current acute or chronic p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
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Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
NCT02201992
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Newport Hospital, Newport, Rhode Island
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
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A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer
NCT05198804
Recruiting
This is a Phase 1/2 study to evaluate the safety, clinical activity, pharmacokinetics (PK), and pharmacodynamics (PD) of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/16/2023
Locations: Women and Infants Hospital of Rhode Island, Providence, Rhode Island
Conditions: Ovarian Cancer, Platinum-resistant Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
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Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
NCT03459456
Recruiting
The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activity in clinically relevant contexts.
Gender:
All
Ages:
Between 21 years and 70 years
Trial Updated:
06/14/2023
Locations: Brown University, Providence, Rhode Island
Conditions: OCD, Obsessive-Compulsive Disorder
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The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Kidney Transplant Rejection
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Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
NCT04500847
Recruiting
This is a randomized, double-blind clinical trial of a daily oral dose of 200 mg emtricitabine vs. placebo in 35 participants with biomarker-confirmed MCI or mild to moderate dementia due to Alzheimer's disease. Study duration for each subject participating in the placebo-controlled research study will be approximately 12 months (up to a 3 months Screening Period, Baseline visit (1 month), 6 months of placebo or emtricitabine dosing, and 1 month follow-up). Participants will have up to 2 months... Read More
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
06/05/2023
Locations: Memory and Aging Program, Butler Hospital, Providence, Rhode Island
Conditions: Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Moderate Dementia
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Elevate! : An Elderly Breast Cancer Cohort Study
NCT03818087
Recruiting
This study is focused on understanding how the investigators can improve upon breast cancer and health outcomes for older participants with breast cancer.
Gender:
Female
Ages:
70 years and above
Trial Updated:
06/05/2023
Locations: Lifespan Cancer Institute, Providence, Rhode Island
Conditions: Breast Cancer
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Exercise Incentives for YMCA Based Exercise
NCT05704712
Recruiting
The investigators will conduct a randomized controlled trial to test financial incentive programs (versus control) to promote physical activity among 330 adults who have a YMCA membership. Participants will have the opportunity to earn up to $100 or $200 (depending on the condition they are assigned to) for attending at least 50 sessions at the YMCA over 6 months. Participants will have two 6-month windows during which they will have the opportunity to earn the incentive. In addition to the ince... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Physical Inactivity
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Weight Management Intervention in College: A Pilot Study
NCT05895461
Recruiting
This Proof-of-Concept study consists of a series of uncontrolled pilot studies to refine a behavioral weight loss trial using a "small change" approach for emerging adult college students with overweight/obesity. The primary aim of this study is maximize student acceptability of the intervention and weight loss outcomes.
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
05/31/2023
Locations: The Miriam Hospital, Providence, Rhode Island
Conditions: Obesity
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DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
NCT04165564
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: Brown University [Administrative Site], Providence, Rhode Island
Conditions: Pulmonary Disease
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iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children
NCT03815019
Recruiting
This is a multi-center, randomized, placebo-controlled, double-blind clinical trial. The primary focus of the study is the evaluation of the effectiveness of treatment with megestrol as part of a 24 week behavioral feeding protocol in transitioning from tube to oral feedings in a pediatric population. Approximately 60 pediatric subjects matching the criteria for eligibility will be enrolled in the study and randomized to receive either megestrol (n=30) or placebo (n=30).
Gender:
All
Ages:
Between 9 months and 108 months
Trial Updated:
05/15/2023
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Feeding Behavior, Feeding Disorder of Infancy or Early Childhood
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Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
NCT05855655
Recruiting
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698). Researchers have completed Aims 1 and 2 of the broader study. Aim 1 used qualitative, community engaged methods, along with a quantitative online survey, to inform intervention development with the study population. Aim 2 involved seeking feedback on the developed mindfulness program through an... Read More
Gender:
Male
Ages:
Between 18 years and 34 years
Trial Updated:
05/04/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Hiv, Minority Stress, Mental Health Wellness 1
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