There are currently 2877 clinical trials in Houston, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including M D Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Baylor College of Medicine and The University of Texas - MD Anderson Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
NCT05629208
Recruiting
The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) in participants with CLE. Information on what is happening in the body relating to CLE, how the body processes, is affected by and responds to the study drug, and any study drug side effects will also be collected in this study.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/25/2025
Locations: Gulf Bank Medical Center, Houston, Texas
Conditions: Cutaneous Lupus Erythematosus (CLE)
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Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients with Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).
NCT05681039
Recruiting
To learn if treatment with tiragolumab and atezolizumab before and after standard of care surgery and chemoradiation (radiation therapy with or without cisplatin/carboplatin) can help to control OCSCC that is PD-L1 CPS positive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma
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Kidney Health: Eat Well, Live Well
NCT05970341
Recruiting
This two-arm, parallel randomized trial study will assess the efficacy of a 6-month (26 weeks) community-based program in reducing kidney injury (as Urine Albumin to Creatinine ratio, uACR), cardiovascular risk (as Hemoglobin A1C and blood pressure), mental health (as PHQ-8) and diet quality (as fruits and vegetables intake and Healthy Eating Index) in community-dwelling, low-income adults diagnosed with early chronic kidney disease (stages 2 or 3 and not on kidney replacement therapies) compare... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Harris Health System's Outpatient Center, Houston, Texas +2 locations
Conditions: Chronic Kidney Diseases
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Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer
NCT06127836
Recruiting
The purpose of this study is to compare two types of imaging for sentinel lymph node (SLN) mapping in people with early-stage vulvar cancer. The researchers will compare indocyanine green near-infrared (ICG-NIR) imaging with lymphoscintigraphy. All participants in this study will be scheduled for standard surgical treatment at Memorial Sloan Kettering Cancer Center (MSK). This surgical treatment includes SLN mapping (with both lymphoscintigraphy and ICG-NIR imaging) and SLN biopsy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Houston Methodist Cancer Center (Data Collection Only), Houston, Texas
Conditions: Vulvar Cancer
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Living Longer and Stronger With Spinal Cord Injury (SCI)
NCT06227000
Recruiting
The purpose of this study is to develop a health promotion group intervention to meet the unique health promotion needs of people aging with SCI, to test the efficacy of the adapted intervention program, Living Longer and Stronger with SCI, in a randomized controlled trial and to assess the mechanisms through which the intervention may enhance physical, psychological, and social health.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: TIRR Memorial Hermann Spinal Cord Injury and Disability Research Center, Houston, Texas
Conditions: Spinal Cord Injuries
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Microphthalmia, Anophthalmia, and Coloboma Genetic Epidemiology in Children
NCT06293560
Recruiting
The investigators are inviting families to take part in a research study that will help us better understand the physical characteristics associated with children who have Microphthalmia, Anophthalmia, and Coloboma (MAC) and how changes in their DNA sequence, called genetic mutations, play a role in the risk of developing MAC
Gender:
ALL
Ages:
All
Trial Updated:
03/25/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Microphthalmia, Coloboma, Anophthalmia
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SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults with CD33 And/or FLT3 Blood Cancers Including AML/MDS
NCT06325748
Recruiting
This is an open-label study of the safety, biodynamics, and anti-cancer activity of SENTI-202 (an off-the-shelf logic gated CAR NK cell therapy) in patients with CD33 and/or FLT3 expressing blood cancers, including AML and MDS.
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
03/25/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: AML/MDS, CD33 Expressing Hematological Malignancies, FLT3 Expressing Hematological Malignancies
Register for Updates
Advancing Discussions Using a Video-based Support Tool About End-of-life Care
NCT06804226
Recruiting
The purpose of this study is to evaluate the effectiveness and implementation considerations of a video aid to improve communication and patient-centered outcomes in older injured adults
Gender:
ALL
Ages:
65 years and above
Trial Updated:
03/25/2025
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Traumatic Injury
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The Effect of Uterine Entry in Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
NCT06829901
Recruiting
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of chorioamniotic membrane separation.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Texas Children's Hospital - Pavilion for Women, Houston, Texas
Conditions: Twin to Twin Transfusion
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Supporting Informed Decision Making About Multi-cancer Early Detection Testing
NCT06870916
Recruiting
To develop a new participant educational aid that can be used by participants to support informed decision-making about Multi-Cancer Early Detection (MCED) tests, which are new blood-based screening tests.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/25/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Multi-cancer Early Detection
Register for Updates
OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection
NCT06343350
Recruiting
In the United States, only 62% of the 37 million people with diabetes receive annual screening exams for diabetic retinopathy. One of the goals of the US Department of Health and Human Services Healthy People 2030 campaign is to increase diabetic retinopathy screening rates to 70.3%. Research indicates that low screening rates are associated with a variety of factors, including income levels, race and lack of access to care. Furthermore, because diabetic retinopathy frequently presents asymptoma... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/24/2025
Locations: Gulf Coast Clinical Research, Houston, Texas
Conditions: Diabetic Retinopathy, Diabetes
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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
NCT06504589
Recruiting
The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to inform CF research, help design CF clinical trials and support the development of new treatments for people with CF who do not take CFTR modulators. Another goal of this study is to learn about research... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/24/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Cystic Fibrosis
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