There are currently 2865 clinical trials in Houston, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including M D Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Baylor College of Medicine and The University of Texas - MD Anderson Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
TRIAD Appendicitis Decision-making Surveys
NCT05887414
Recruiting
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Lyndon B Johnson- Harris Health, Houston, Texas +1 locations
Conditions: Appendicitis
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A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.
NCT04822233
Recruiting
The purpose of this study is to compare the effectiveness of the Hall technique and modified Hall technique to the conventional Stainless-Steel Crown restoration in the treatment of primary molars with dentinal caries with or without proximal ridge intact.
Gender:
ALL
Ages:
Between 5 years and 8 years
Trial Updated:
05/18/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Dental Caries
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Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury
NCT05601661
Recruiting
The purpose of this study is to determine the safety and feasibility of pairing vagus nerve stimulation (VNS) with rehabilitation and to determine the efficacy of pairing VNS with rehabilitation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Cervical Spinal Cord Injury
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JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors
NCT04720976
Recruiting
To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Research Site, Houston, Texas
Conditions: Solid Tumor, NSCLC
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Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies
NCT05487651
Recruiting
This study is a multi-center study to evaluate the safety of KUR-502 in subjects with refractory/relapsed B-cell NHL or leukemia (ALL or CLL).
Gender:
ALL
Ages:
Between 3 years and 75 years
Trial Updated:
05/16/2023
Locations: Baylor College of Medicine, Houston, Texas
Conditions: NHL, Relapsed, Adult, B-cell Lymphoma, B-cell Leukemia, DLBCL - Diffuse Large B Cell Lymphoma, ALL, Adult B Cell, ALL, Childhood, CLL/SLL
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ROSE-Longitudinal Assessment With Neuroimaging
NCT05089331
Recruiting
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: Houston Methodist, Houston, Texas
Conditions: Intracerebral Hemorrhage
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The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.
NCT04489472
Recruiting
The purpose of this study is to determine the effect of a dietary supplement rich in nitric oxide (NO) on nasal nitric oxide and fractional exhaled nitric oxide (FeNO),on ciliary beat frequency assessed by high-speed digital video microscopy and on lung function assessed by spirometry in normal patients and patients with Primary ciliary dyskinesia (PCD).
Gender:
ALL
Ages:
Between 4 years and 99 years
Trial Updated:
05/10/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Primary Ciliary Dyskinesia
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An Enhanced Home-Based Telemedicine Program Using Remote Examination Devices for Children With Medical Complexity
NCT05408143
Recruiting
The purpose of this study is to assess if the benefits for children with medical complexity (CMC) receiving comprehensive care (CC) in an enhanced medical home can be further improved by enhanced telemedicine program (ETM) provided during clinic hours using mobile devices to measure temperature\& oxygen saturation, auscultate the heart \& lungs, and view the skin, throat, \& tympanic membranes in the home.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
05/10/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Chronic Diseases in Children
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COVID-19 Outcome Prediction Algorithm
NCT05471011
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
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Strawberry Candy Twists as an Alternative Screen for Gestational Diabetes: A Prospective Trial
NCT02610179
Recruiting
The goal of this prospective study is to determine whether there is superiority of 10 Twizzlers to the 50 gram glucola beverage for screening for GDM in a population based study.
Gender:
FEMALE
Ages:
Between 18 years and 64 years
Trial Updated:
05/09/2023
Locations: Ben Taub General Hospital, Houston, Texas
Conditions: Gestational Diabetes Mellitus
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Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
NCT04005976
Recruiting
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Aortic Aneurysm, Aortic Dissection, Aortic Diseases
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KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
NCT03662126
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition of MDM2 is a novel mechanism of action in MF. This study will be conducted in 2 phases. Phase 2 will determine the KRT-232 recommended dose and dosing schedule; Phase 3 will test KRT-232 vs Best Available Therapy (BAT). Patients in the Phase 3 part of the study will be randomized 2:1 to receive ei... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Post-Essential Thrombocythemia MF (Post-ET-MF)
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