Connecticut is currently home to 1248 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
NCT06413433
Recruiting
ENGAGE (Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol) is a Phase 3, randomized, double-blind, placebo-controlled, multicenter trial to assess the efficacy and safety of solriamfetol for the treatment of binge eating disorder (BED) in adults.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/21/2025
Locations: Clinical Research Site, Cromwell, Connecticut
Conditions: Binge-Eating Disorder
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Building an Equitable and Accessible System of Eating Disorder Care for VA, DoD, and Underrepresented Americans
NCT05304104
Recruiting
When untreated, eating disorders present with tremendous burdens to affected active duty Service members and Veterans and their families, and are very costly to the DoD and VA healthcare system. A comparative effectiveness study with state-of-the-art virtual treatment for BN and BED specifically adapted for testing with the Veteran population and other underrepresented eating disorder populations will lead to major improvements in clinical outcomes. The treatment will be integrated with VA's new... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: VA Connecticut Healthcare System, West Haven, Connecticut
Conditions: Binge-Eating Disorder, Bulimia Nervosa, Veterans Health, Cognitive Behavioral Therapy
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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
NCT02493478
Recruiting
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
Gender:
ALL
Ages:
All
Trial Updated:
01/21/2025
Locations: Yale New Haven Children's Hospital, New Haven, Connecticut
Conditions: Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
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External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy
NCT06788977
Recruiting
This online registry aims to understand the potential benefits and safety of external trigeminal nerve stimulation for the treatment of migraine in pregnant women. Women do not need to use external trigeminal nerve stimulation or any other form of migraine treatment to participate in the registry. The main question it aims to answer is: Is external trigeminal nerve stimulation a safe and effective option for migraine treatment during and after pregnancy? There are no required changes in migra... Read More
Gender:
FEMALE
Ages:
Between 18 years and 44 years
Trial Updated:
01/17/2025
Locations: https://public.smart-trial.co/#/public/649d77f0e8f8d0fb993d0c61/6626f6a04f0a3c7dd0860e14/662726d84f0a3c7dd08aeaa0/signup?lang=en-us&enforceLanguage=true, Darien, Connecticut
Conditions: Pregnancy, Migraine, Headache, Postpartum, Depression, Anxiety
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The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
NCT06027554
Recruiting
The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cognitive dysfunction. The main question\[s\] it aims to answer are: * To compare vascular function, oxidative stress levels, and physical and cognitive function among older adults and frail older adults with physical and cognitive dysfunction * To determine whether MitoQ supplementation has the potential to improve vascular function in central... Read More
Gender:
ALL
Ages:
Between 65 years and 80 years
Trial Updated:
01/16/2025
Locations: UConn Health, Farmington, Connecticut
Conditions: Frailty, Mild Cognitive Impairment, Aging
Register for Updates
HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
NCT06513819
Recruiting
The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
01/15/2025
Locations: VA Connecticut Healthcare System, West Haven, Connecticut
Conditions: Hiv, Alcohol Drinking, Fall, Cannabis Use
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FSL2 Post Approval Study for Pediatric and Young Adults Patients
NCT04959552
Recruiting
This is a prospective, multi-center, non-randomized, single-arm study intended to characterize the safety of the FreeStyle Libre 2 Flash Glucose Monitoring System when used to manage diabetes in pediatric and young adult patient populations.
Gender:
ALL
Ages:
Between 4 years and 30 years
Trial Updated:
01/14/2025
Locations: Yale Pediatric Endocrinology Clinic, New Haven, Connecticut
Conditions: Diabete Mellitus
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Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)
NCT05776563
Recruiting
The goal of this clinical trial is to learn about the effects of high blood glucose levels in the brain and assess if the changes seen in individuals with poorly control T2DM can be reversed with good glucose control. The main question\[s\] it aims to answer are: * To determine, whether abnormalities in brain glucose transport seen in individuals with uncontrolled diabetes, can be improved with better glucose control. * Assess which factors, (duration of diabetes mellitus (DM) and glycemic con... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/10/2025
Locations: Yale New Haven Hospital (YNHH) Research Unit (HRU), New Haven, Connecticut
Conditions: Diabetes Mellitus, Type 2
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 1
NCT05323487
Recruiting
This study will employ a randomized order, double-blind, repeated measures dose ranging design. This design was chosen in order to generate multiple within-subject serial loop diuretic dose response exposures. The overall study schema will include 75 heart failure (HF) patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure
Register for Updates
Combined THC and CBD for OUD and Chronic Pain
NCT06544291
Recruiting
The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid craving in people with co-occurring opioid use disorder (OUD) and chronic pain who are undergoing methadone therapy.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/09/2025
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Chronic Pain, Opioid Use Disorder
Register for Updates
Adaptation and Implementation of Peer Support in Brazil
NCT05842889
Recruiting
Mental disorders are among the leading causes of disability and morbidity worldwide, including Brazil, where despite having a comprehensive network of publicly-funded, free, community-based mental health treatment, it is estimated that only 26% of people with psychiatric conditions successfully connect to community-based care. The study team hypothesizes that the successful adaptation and implementation of an evidence-based model of peer support to Brazilian culture, will contribute to enhanced... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/09/2025
Locations: Yale University Program for Recovery and Community Health, New Haven, Connecticut
Conditions: Peer Support
Register for Updates
Study of INBRX-109 in Conventional Chondrosarcoma
NCT04950075
Recruiting
Randomized, blinded, placebo-controlled, Phase 2 study of INBRX-109 in unresectable or metastatic conventional chondrosarcoma patients.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/09/2025
Locations: Yale Cancer Center, New Haven, Connecticut
Conditions: Conventional Chondrosarcoma
Register for Updates