Connecticut is currently home to 1218 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness
NCT06006000
Recruiting
This is a prospective longitudinal study that will evaluate the unmet needs of older adults (65 and older) who return home (either directly or after short-term rehab) after an ICU hospitalization, evaluate the association of these unmet needs with clinically relevant outcomes, and assess barriers and facilitators to addressing these unmet needs. The proposed research will inform the development and evaluation of a subsequent intervention to improve functional outcomes among older ICU survivors,... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
06/06/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Critical Illness, Illness, Critical
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Improving Availability of Intranasal Naloxone
NCT05877118
Recruiting
While there is a lifesaving medication called naloxone that can reverse the deadly effects of opioid overdose, patients often fail to fill the prescription at the pharmacy when it is prescribed. This is particularly concerning and true in those at the highest risk of death-those who end up in the emergency department for opioid overdose. The goal of this study is to compare the impact of different overdose education on naloxone prescription fill rates in opioid users being discharged from our ho... Read More
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
06/06/2024
Locations: Hartford Hospital Emergency Department, Hartford, Connecticut
Conditions: Opioid Overdose
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Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy
NCT05374564
Recruiting
18F-Flutemetamol (Vizamyl) is a radioactive diagnostic agent indicated and FDA-approved for Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline. This study is designed to evaluate a novel use for 18F-Flutemetamol in cardiac amyloidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Cardiomyopathies, Primary
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BXCL501 for Agitation in Schizophrenia
NCT03708315
Recruiting
Agitation is characterized by excessive motor or verbal activity, irritability, uncooperativeness, threatening gestures, and, in some cases, aggressive or violent behavior. While agitation may have various underlying causes, patients with schizophrenia are especially vulnerable to acute episodes of agitation, especially during exacerbation of disease, and clinicians do not always diagnose these episodes early enough. Agitation associated with psychosis is a frequent reason for emergency departme... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/06/2024
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Schizophrenia, Schizoaffective Disorder
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Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery
NCT06445413
Recruiting
The goal of this clinical trial is to evaluate the feasibility and acceptability of a 10-wk hybrid Tai Chi (TC) program with in-person classes and online TC videos among 24 physically inactive adults who are seeking metabolic and bariatric surgery (MBS) in a single-arm trial. The aims are: Aim 1: Feasibility: To evaluate whether TC is feasible, defined as a mean attendance rate of ≥70% in-person TC classes attended. Aim 2: Acceptability: To evaluate whether TC is acceptable, defined as a mean... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/04/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Obesity
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Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Bronchiolitis Acute Viral
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
NCT05753059
Recruiting
Randomized placebo-controlled, double-blind, double-dummy, crossover design testing combinations placebo/placebo, bendroflumethiazide/placebo, amiloride/placebo, and bendroflumethiazide/amiloride added to bumetanide.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure
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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
NCT05313165
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
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OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
NCT05911646
Recruiting
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA). Our hypothesis is that in children with mild OSA there is significant conflict with parental decision-making; in the absence of significant sleep apnea, there is limited research regarding comparative efficacy of various treatment options. The impact of a QOL questionnaire can be a significant deciding factor and may... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
05/30/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Apnea, Obstructive Sleep, Obstructive Sleep Apnea
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Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy
NCT05730309
Recruiting
The objective of the proposed project is to quantify the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in Emergency Department (ED) patients with persistently elevated asymptomatic BP, and to measure the effect of disclosure, education, and expedited referral on 3-month outpatient follow-up and treatment rates for ED patients with newly diagnosed LVH by POCUS. Additionally, investigators will create a database of annotated clips for future development of a machine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Left Ventricular Hypertrophy
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The Study of NC318 Alone or in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer
NCT04699123
Recruiting
This is a phase 2 study to investigate NC318 alone or in combination with Pembrolizumab in patients with advanced non-small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Advanced Non-small Cell Lung Cancer
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Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
NCT04291612
Recruiting
This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Hartford Healthcare Cancer Institute @ Hartford Hospital, Hartford, Connecticut
Conditions: Endometrial Cancer, Endometrioid Adenocarcinoma, Endometrial Cancer Stage I
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