Alabama Clinical Trials

A listing of Alabama clinical trials actively recruiting patient volunteers.

Found in the southeastern United States, people love exploring Alabama for its 1,500 miles of inland waterways. Known as "The Heart of Dixie" and "The Cotton State," the biggest cities include Montgomery, Birmingham, Auburn, and Mobile. Today, Alabama has a diverse economy and one of the most active college athletics scenes in the United States. The University of Alabama Crimson Tide is one of the "winningest" college athletic programs in the country, with football head coach Nick Saban a true local celebrity. UAB Hospitaland the regional Huntsville Hospital are the largest healthcare providers, with the latter serving northern Alabama.

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1326 trials found

Safety of Co-Administered CHI-554 and Alcohol

NCT05317507

This is a Phase 1, randomized, double-blind study to assess the safety, tolerability, and effects of CHI-554 when co-administered with alcohol.

Conditions: Healthy Adults

Safety and Efficacy of Lacutamab in Patients With Relapse Peripheral T-cell Lymphoma That Express KIR3DL2

NCT05321147

This is a multi-center phase Ib sutdy, which evaluates the safety and efficacy of lacutamab monotherpy in patients with relapse peripheral T-cell lymphoma that express KIR3DL2.

Conditions: Peripheral T Cell Lymphoma

Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis (CLARITY)

NCT05324397

The CLARITY Study is a prospective, single-arm, multicenter safety and efficacy study of the Neurent Medical NEUROMARK System in subjects with chronic rhinitis.

Conditions: Chronic Rhinitis
Phase: Not Applicable

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

NCT05329194

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied populations in the United States.

Conditions: Asthma

A Study of JNJ-55308942 in the Treatment of Bipolar Depression

NCT05328297

The purpose of this study is to evaluate the efficacy of JNJ-55308942 compared to placebo on symptoms of depression in participants with bipolar disorder (BD) in a major depressive episode (MDE) at Week 6.

Conditions: Bipolar Disorder

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥50 Years of Age

NCT05330975

The main purposes of this study are to evaluate the safety and tolerability of mRNA-1345 coadministered with a seasonal influenza vaccine (Afluria® Quadrivalent); to evaluate the impact of coadministered influenza vaccine on the immune response to RSV; and to evaluate the impact of coadministered RSV vaccine on the immune response to influenza.

Conditions: Respiratory Syncytial Virus

Assessing Malleability of Spatial Abilities in Down Syndrome

NCT05332912

Based on available literature and our own preliminary research, the researchers have concluded that persons with Down syndrome (DS) exhibit difficulties in utilizing the specific spatial abilities of mental rotation and perspective taking and performing complex spatial tasks such as wayfinding and environmental learning. A weakness in spatial abilities may have many direct applications to daily life, ranging from activities such as tying shoes to using hand tools and navigating the environment. ...

Conditions: Down Syndrome
Phase: Not Applicable

Low-GI Diet vs High-GI Diet in Individuals With SCI

NCT05334342

The purpose of this pilot research project is to examine the impact of a low-glycemic index (GI) diet on postprandial hypotension and glucose control in individuals with chronic spinal cord injury. The objectives are: 1) To evaluate the effect of the low-GI diet on the magnitude of postprandial systolic blood pressure drop compared to a high-GI control diet. 2)To evaluate the effect of a low-GI diet on postprandial glucose and insulin responses compared to a high-GI control diet.

Conditions: Spinal Cord Injuries, Postprandial Hypotension, Glucose Metabolism Disorders
Phase: Not Applicable

TruGraf and TRAC In Pediatrics Study

NCT05335538

This is a pilot 3 center prospective study of pediatric renal kidney recipients undergoing protocol biopsies examining the performance of the TruGraf gene expression test in children and adolescents.

Conditions: Kidney Transplant Rejection

Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy

NCT05336227

The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group. The secondary purpose is to understand behavioral mechanisms that explain participation in exergaming through semi-structured interviews with participants from both groups at post-intervention or dropout.

Conditions: Cerebral Palsy

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

NCT05348733

This is an observational study in people with chronic kidney disease (CKD) and type 2 diabetes (T2D) who will be receiving finerenone. Kidneys filter extra water and waste out of the blood and make urine. CKD is a long-term, progressive, decrease in the kidneys' ability filter the blood properly. In people with T2D, the body does not make enough of a hormone called insulin, or does not use insulin well enough, resulting in high blood sugar levels that can cause damage to the kidneys. As a resul ...

Conditions: Chronic Kidney Disease, Type 2 Diabetes Mellitus

Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids

NCT05348200

A Randomized Phase 2 double blind study which aims to determine the safety and efficacy of CITI-002 cream in adult patients with Goligher's grade II or III hemorrhoids.

Conditions: Hemorrhoids