Arkansas is currently home to 735 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Little Rock, Jonesboro, Hot Springs and Fayetteville. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single-dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis
NCT06055361
Recruiting
The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of a single SC dose of BxC-I17e in patients with moderate to severe atopic dermatitis (AD)
Gender:
All
Ages:
18 years and above
Trial Updated:
09/20/2023
Locations: Arkansas Research Trials, North Little Rock, Arkansas
Conditions: Atopic Dermatitis
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Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer
NCT05403385
Recruiting
Part 1 of the study determines the optimal dose of inupadenant to be given in combination with carboplatin and pemetrexed to patients that progressed after receiving specific first line treatments for Stage 3 or metastatic non-small cell lung cancer. Part 2 compares the efficacy of inupadenant to placebo when both are combined with carboplatin and pemetrexed for patients that progressed after receiving the same first line treatments for Stage 3 or metastatic non-small cell lung cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/20/2023
Locations: Highlands Oncology Group, Fayetteville, Arkansas
Conditions: Metastatic NSCLC, Stage III NSCLC
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The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
NCT05992688
Recruiting
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia (as with other sweeteners and consistent with prior research in children and adults) has benefits for weight control and metabolic function relative to caloric sweeteners, and whether it provides benefits in this regard similar to water.
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
09/19/2023
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Weight Gain, Adiposity, Insulin Sensitivity, Microbial Colonization
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Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia
NCT05545111
Recruiting
This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled, multi-arm, multi-stage inpatient study designed to assess the efficacy, safety, tolerability, and pharmacokinetics (PK) of NBI-1117568 compared with placebo in adult subjects with a primary diagnosis of schizophrenia, who are experiencing an acute exacerbation or relapse of symptoms.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
09/15/2023
Locations: Neurocrine Clinical Site, Little Rock, Arkansas
Conditions: Schizophrenia
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Safety and Efficacy of TU-100 as an Adjunct to an Enhanced Recovery After Surgery in Subjects Undergoing Bowel Resection
NCT04742907
Recruiting
This multicenter, randomized, double-blinded, placebo-controlled study will evaluate the effect of TU-100 on resolution of postoperative ileus (POI) in subjects undergoing open or laparoscopic bowel resection (BR).
Gender:
All
Ages:
18 years and above
Trial Updated:
09/14/2023
Locations: Little Rock Site, Little Rock, Arkansas
Conditions: Enhanced Recovery After Surgery
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ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
NCT03911505
Recruiting
This is a Phase 3, open-label, multicenter study to evaluate the safety, PK, efficacy, PD, and immunogenicity of Cipaglucosidase Alfa/Miglustat treatment in enzyme replacement therapy (ERT)-experienced and ERT-naïve pediatric subjects with Pompe disease, aged 0 to < 18 years
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
09/14/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Pompe Disease (Late-onset)
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High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
NCT05951985
Recruiting
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive. This is an issue for both them and their care partners as their health is often linked. This study aims to examine the long-term physical and psychosocial effects of structured, group-based, high intensity functional training (HIFT) exercise for people with neurologic diagnoses and their care partners.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/08/2023
Locations: Arkansas Colleges of Health Education, Fort Smith, Arkansas
Conditions: Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida, Stroke, Poliomyelitis, Multiple Sclerosis, Brain Injuries
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A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
NCT05614063
Recruiting
The X-TOLE2 Phase 3 clinical trial is a randomized, double-blind, placebo-controlled study that will evaluate the clinical efficacy, safety and tolerability of XEN1101 administered as adjunctive therapy in focal-onset seizures.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2023
Locations: Clinical Trials, Inc, Little Rock, Arkansas
Conditions: Focal Onset Seizures
Register for Updates
Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
NCT05172726
Recruiting
This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis.
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
09/07/2023
Locations: Dermavant Clinical Site, Rogers, Arkansas
Conditions: Plaque Psoriasis
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CLUE: CLinical Utility Study of EsoGuard
NCT06030180
Recruiting
Utilize real-world data from the commercial use of EsoGuard testing on samples collected with EsoCheck (EC/EG) to evaluate the impact of EsoGuard results on health care provider's decision for endoscopy referral. Assess patient compliance with recommendations for upper endoscopy, and relationship of compliance to positive EsoGuard results.
Gender:
All
Ages:
Between 12 years and 99 years
Trial Updated:
09/06/2023
Locations: Arkansas Heartburn Treatment Center, Heber Springs, Arkansas
Conditions: Barrett Esophagus, Barretts Esophagus With Dysplasia, Esophagus Adenocarcinoma
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Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study
NCT04967365
Recruiting
Pediatric Intensive Care Unit (PICU) survival has increased substantially over the past three decades. Currently, an understanding of PICU morbidity and recovery among PICU survivors and their families is limited. Post-intensive care syndrome (PICS) consists of new or worsening impairments in physical, cognitive, or mental health status that arise and may persist after critical illness. The characteristics of PICS in children (PICS-p) are unknown. The objective of this study is to learn about pe... Read More
Gender:
All
Ages:
Between 1 month and 16 years
Trial Updated:
09/06/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Critical Illness, Post Intensive Care Unit Syndrome
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Study of Kidney Tumors in Younger Patients
NCT00898365
Recruiting
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Gender:
All
Ages:
29 years and below
Trial Updated:
09/06/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor, Angiolipoma, Cellular Congenital Mesoblastic Nephroma, Classic Congenital Mesoblastic Nephroma, Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma, Cystic Partially Differentiated Kidney Nephroblastoma, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Extrarenal Rhabdoid Tumor, Kidney Medullary Carcinoma, Kidney Neoplasm, Kidney Oncocytoma, Kidney Wilms Tumor, Metanephric Adenofibroma, Metanephric Adenoma, Metanephric Stromal Tumor, Metanephric Tumor, Mixed Congenital Mesoblastic Nephroma, Ossifying Renal Tumor of Infancy, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions, Rhabdoid Tumor of the Kidney, Wilms Tumor
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