There are currently 47 active clinical trials seeking participants for Autism research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Ohio.
The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
NCT00271622
Recruiting
The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific protocols at NIH.
Gender:
All
Ages:
6 weeks and above
Trial Updated:
06/19/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurologic Disorders, Autism, Neurodegenerative Disease, Neurobehavioral Manifestation
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Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01778504
Recruiting
Background: - Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood. Researchers want to look at people of all ages who have these disorders that started in childhood. They will also look at relatives of people with these disorders. This information will allow doctors to learn more about childhood behavioral problems and how they are inherited. It may also help doct... Read More
Gender:
All
Ages:
99 years and below
Trial Updated:
06/19/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurological Disorder, Autism, Sleep
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Pilot Trial of Pregnenolone in Autism
NCT02627508
Recruiting
This is a research study to examine the tolerability and effectiveness of pregnenolone in individuals with autism. Pregnenolone is a naturally occurring steroid hormone in the brain that has been implicated in treating various psychiatric conditions. The investigators hope to learn the effects and safety of using pregnenolone in reducing irritability and sensitivity to sensory differences and improving social communication in individuals with autism. The investigators hope by studying the effect... Read More
Gender:
All
Ages:
Between 14 years and 25 years
Trial Updated:
06/18/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
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Trial of Zolpidem for Sleep in Children With Autism
NCT05540574
Recruiting
The purpose of this study is to examine the effect of zolpidem on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Zolpidem is a nonbenzodiazepine GABAa receptor agonist drug that acts as a hypnotic. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of zolpidem on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
All
Ages:
Between 8 years and 17 years
Trial Updated:
06/18/2024
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
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Trial of Suvorexant for Sleep in Children With Autism
NCT05546554
Recruiting
The purpose of this study is to examine the effect of suvorexant on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Suvorexant is a selective, dual orexin receptor antagonist (DORA) used for the treatment of sleep onset difficulties and/or sleep maintenance. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of suvorexant on sleep physiology as assessed by polysomnography (PSG), ac... Read More
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
06/18/2024
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
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CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings
NCT05031364
Recruiting
This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety). We will randomly assign 50 mental health clinicians, each treating 2 youth (N = 100 youth total), to CBT program for emotional dysregulation and core autism symptoms with weekly live consultation with an expert or to usual clinical care augmented by self-instruction in CBT, in... Read More
Gender:
All
Ages:
Between 6 years and 14 years
Trial Updated:
06/08/2024
Locations: Westside Regional Center, Culver City, California +2 locations
Conditions: Autism
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Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
NCT03434080
Recruiting
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This ma... Read More
Gender:
All
Ages:
Between 3 months and 5 years
Trial Updated:
06/07/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Autism, Cerebral Palsy
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Trial of Diphenhydramine for Sleep in Children With Autism
NCT05501678
Recruiting
The purpose of this study is to examine the effect of diphenhydramine on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Diphenhydramine is an anti-histaminergic agent with strong hypnotic properties. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of diphenhydramine on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
All
Ages:
Between 8 years and 17 years
Trial Updated:
05/28/2024
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
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Improving Access to Community-Based Occupations Via a Rideshare Training Program
NCT06323850
Recruiting
Community mobility is critical for living independently and engaging in one's community. It is especially important for people in their early adult years, as this is often a time of transition to employment and living independently. Community mobility can be particularly challenging for adults with Autism Spectrum Disorders (ASD) (henceforth referred to as autistic adults based on the preferred identity-first language of our autistic partners). Some autistic adults are unable to meet the demands... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Autism
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SenseToKnow Autism Screening Device Validation Study
NCT05874466
Recruiting
This is a pivotal, prospective, double-blind, study to evaluate the sensitivity and specificity of the SenseToKnow app for the detection of autism spectrum disorder in children 16-36 months of age.
Gender:
All
Ages:
Between 16 months and 36 months
Trial Updated:
05/21/2024
Locations: Duke University, Durham, North Carolina
Conditions: Autism, Autism Spectrum Disorder
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Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
NCT05741840
Recruiting
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
05/13/2024
Locations: UC San Diego Center for Healthy Eating and Activity Research (CHEAR), La Jolla, California
Conditions: Autism Spectrum Disorder, Obesity, Childhood, Autism
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Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
NCT06208722
Recruiting
The goal of this proposed trial will modify an existing toothbrushing app for teens with autism and compare toothbrushing outcomes with a control app. We have 2 specific aims: During the 2-year UG3 phase, we will use the Discover, Design+Build, and Test Framework to modify our existing app and pilot the intervention. During the 4-year UH3 phase, we will recruit 270 pre-adolescents and teens with autism ages 10 to 17 years, randomize participants to one of two arms, and compare outcomes. Partic... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
05/06/2024
Locations: University of Washington, Seattle, Washington
Conditions: Autism
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