Non-Small Cell Lung Cancer Clinical Trials

A listing of 141 Non-Small Cell Lung Cancer clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

All Conditions

Non-Small Cell Lung Cancer

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

There are currently 141 active clinical trials seeking participants for Non-Small Cell Lung Cancer research studies. The states with the highest number of trials for Non-Small Cell Lung Cancer participants are California, Texas, Florida and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

NCT06463665

Recruiting

This Phase 2, open-label, randomized study in non-small-cell lung cancer (NSCLC) is designed to evaluate the efficacy and safety of an intravenously delivered oncolytic vaccinia virus, Olvi-Vec, followed by platinum-doublet chemotherapy + Physician's Choice of Immune Checkpoint Inhibitor (ICI) vs. docetaxel for patients with advanced or metastatic NSCLC who have shown first disease progression (i.e., progressive disease not yet confirmed by further scan after initial scan showing progression) wh... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Pioneer Research Center, LLC, Bullhead City, Arizona +10 locations

Conditions: Advanced Non-squamous Non-small-cell Lung Cancer, Advanced Squamous Non-Small Cell Lung Carcinoma, Metastatic Non-squamous Non Small Cell Lung Cancer, Metastatic Squamous Non-Small Cell Lung Carcinoma, Non-small Cell Lung Cancer, Non-small Cell Lung Cancer Stage III, Non-small Cell Lung Cancer Stage IV, Non-small Cell Lung Cancer Recurrent

Learn More ›

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

NCT04886804

Recruiting

The study has 2 parts. The first part is open to adults with different types of advanced cancer (solid tumours with changes in the HER2 gene) for whom previous treatment was not successful. The second part is open to people with non-small cell lung cancer with a specific mutation in the HER2 gene. The purpose of the first study part is to find the highest dose of a medicine called zongertinib the participants can tolerate. Once this dose is found, it will be used in the second study part to te... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +84 locations

University of Alabama at Birmingham, Birmingham, Alabama

Precision NextGen Oncology, Beverly Hills, California

City of Hope-Duarte-56419, Duarte, California

City of Hope - Seacliff, Huntington Beach, California

City of Hope-Irvine-69674, Irvine, California

Valkyrie Clinical Trials, Los Angeles, California

University of California Irvine, Orange, California

University of California Davis, Sacramento, California

Georgetown University, Washington, District of Columbia

Holy Cross Hospital-Fort Lauderdale-57892, Fort Lauderdale, Florida

Winship Cancer Institute, Atlanta, Georgia

Hawaii Cancer Care - Honolulu, Honolulu, Hawaii

Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York, New York

Duke University Medical Center, Durham, North Carolina

Cleveland Clinic, Cleveland, Ohio

Sarah Cannon Research Institute-Nashville-48456, Nashville, Tennessee

Mary Crowley Cancer Research Center, Dallas, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

Virginia Cancer Specialists, PC, Fairfax, Virginia

Fred Hutchinson Cancer Research Center, Seattle, Washington

Macquarie University, Macquarie Park, New South Wales

KH der Barmherzigen Schwestern Linz, Linz, Not set

Brussels - HOSP Jules Bordet, Anderlecht/Brussels-Capital, Not set

Beijing Cancer Hospital, Beijing, Not set

Jilin Province Cancer Hospital, Changchun, Not set

The First Hospital of Jilin University, Changchun, Not set

Fujian Cancer Hospital, Fuzhou, Not set

Guangdong Provincial People's Hospital, Guangzhou, Not set

The First Affiliated Hospital, Zhejiang University, Hangzhou, Not set

Zhejiang Cancer Hospital, Hangzhou, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

The Affiliated Cancer Hospital, Guangxi Medical University, Nanning, Not set

Shanghai Chest Hospital, Shanghai, Not set

Wuhan Union Hospital, Wuhan, Not set

Tongji Hospital Affiliated Tongji Medical College Huazhong University of S & T, Wuhan, Not set

First Affiliated Hospital of Xiamen University, Xiamen, Not set

Henan Cancer Hospital, Zhengzhou, Not set

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

HOP Louis Pradel, Bron, Not set

CTR Leon Berard, Lyon, Not set

HOP Timone, Marseille, Not set

INS Curie, Paris, Not set

HOP Pontchaillou, Rennes, Not set

INS Gustave Roussy, Villejuif, Not set

Universitätsklinikum Augsburg, Augsburg, Not set

Technische Universität Dresden, Dresden, Not set

Justus-Liebig Universität Gießen, Gießen, Not set

Universitätsklinikum Köln (AöR), Köln, Not set

Pius-Hospital, Oldenburg, Oldenburg, Not set

Prince of Wales Hospital-Hong Kong-20715, Hong Kong, Not set

Queen Mary Hospital, Hong Kong, Not set

Rambam Medical Center, Haifa, Not set

Meir Medical Center, Kfar Saba, Not set

Sourasky Medical Center, Tel Aviv, Not set

The Chaim Sheba Medical Center Tel HaShomer, Tel Hashomer, Not set

Istituto Di Candiolo, Candiolo (TO), Not set

Istituto Nazionale IRCCS Tumori Fondazione Pascale, Napoli, Not set

Azienda Ospedaliera Unversitaria di Parma, Parma, Not set

National Cancer Center Hospital East, Chiba, Kashiwa, Not set

Shikoku Cancer Center, Ehime, Matsuyama, Not set

Hiroshima University Hospital, Hiroshima, Hiroshima, Not set

Kindai University Hospital, Osaka, OsakaSayama, Not set

Osaka International Cancer Institute, Osaka, Osaka, Not set

Hamamatsu University Hospital, Shizuoka, Hamamatsu, Not set

National Cancer Center Hospital, Tokyo, Chuo-ku, Not set

Chungbuk National University Hospital, Cheongju-si, Not set

Seoul National University Bundang Hospital, Seongnam, Not set

Severance Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Nederlands Kanker Instituut, Amsterdam, Not set

Leids Universitair Medisch Centrum (LUMC), Leiden, Not set

Hospital CUF Porto, Porto, Not set

National University Hospital-Singapore-22806, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Hospital Vall d'Hebron, Barcelona, Not set

Hospital Duran i Reynals, L'Hospitalet de Llobregat, Not set

Hospital General Universitario Gregorio Marañón, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Virgen de la Victoria, Malaga, Not set

Hospital Clínico de Valencia, Valencia, Not set

Karolinska Universitetssjukhuset Solna, Stockholm, Not set

The Royal Marsden Hospital, Chelsea, London, Not set

Hammersmith Hospital, London, Not set

The Royal Marsden Hospital, Sutton, Sutton, Not set

Conditions: Neoplasm Metastasis, Non-Small Cell Lung Cancer

Learn More ›

AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

NCT06333951

Recruiting

The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted thoracic tumors. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced MTAP-deleted thoracic... Read More

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

06/25/2025

Locations: Comprehensive Blood and Cancer Center, Bakersfield, California +71 locations

Comprehensive Blood and Cancer Center, Bakersfield, California

City of Hope National Medical Center, Duarte, California

Translational Research in Oncology US Inc, Trio Central Pharmacy, Los Angeles, California

University of California Irvine, Orange, California

University of California Los Angeles, Santa Monica, California

Rocky Mountain Cancer Centers, Denver, Colorado

Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut

HealthPartners Institute, Saint Paul, Minnesota

Saint Lukes Hospital of Kansas City, Kansas City, Missouri

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada

New York University Grossman School of Medicine, New York, New York

Perlmutter Cancer Center at New York University Langone Hospital----Long Island, New York, New York

Hightower Clinical, Oklahoma City, Oklahoma

University of Tennessee Medical Center Knoxville, Knoxville, Tennessee

United States Oncology Regulatory Affairs Corporate Office, Nashville, Tennessee

Texas Oncology - Dallas Fort Worth, Dallas, Texas

US Oncology Research Investigational Products Center, Dallas, Texas

Oncology Consultants Cancer Center, Houston, Texas

Texas Oncology Northeast Texas, Tyler, Texas

Virginia Cancer Specialists PC, Fairfax, Virginia

Northwest Medical Specialties, PLLC, Tacoma, Washington

Orange Health Service, Orange, New South Wales

The Queen Elizabeth Hospital, Woodville South, South Australia

Medizinische Universitaet Graz, Graz, Not set

Medizinische Universitaet Innsbruck, Innsbruck, Not set

Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, Not set

Oncosite Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, Rio Grande Do Sul

Beneficencia Portuguesa de Sao Paulo - Bp, Sao Paulo, São Paulo

Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp, São Paulo, Not set

Princess Margaret Cancer Centre, Toronto, Ontario

Mengchao Hepatobiliary hospital of Fujian Medical University, Fuzhou, Fujian

Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

Jilin Cancer Hospital, Changchun, Jilin

West China Hospital of Sichuan University, Chengdu, Sichuan

Beijing Cancer Hospital, Beijing, Not set

Institut Bergonie, Bordeaux, Not set

Hopital de la Timone, Marseille, Not set

Institut de Cancerologie de l Ouest Rene Gauducheau, Saint Herblain, Not set

Gustave Roussy, Villejuif, Not set

Universitaetsklinikum Essen, Essen, Not set

Thoraxklinik Heidelberg, Heidelberg, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Alexandra Hospital, Athens, Not set

Saint Luke Hospital, Thessaloniki, Not set

General Hospital Of Thessaloniki Papageorgiou, Thessaloniki, Not set

Queen Mary Hospital, The University of Hong Kong, Hong Kong, Not set

Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Alessandria, Not set

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Not set

IRCCS Istituto Clinico Humanitas, Rozzano (MI), Not set

Centro Ricerche Cliniche Di Verona Societa responsabilita limitata, Verona, Not set

Aichi Cancer Center, Nagoya-shi, Aichi

National Cancer Center Hospital East, Kashiwa-shi, Chiba

Shizuoka Cancer Center, Sunto-gun, Shizuoka

Wakayama Medical University Hospital, Wakayama-shi, Wakayama

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Radboud Universitair Medisch Centrum, Nijmegen, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Narodowy Instytut Onkologii im Marii Slodowskiej Curie Panstwowy Instytut Badawczy, Gliwice, Not set

Futuremeds spolka z ograniczona odpowiedzialnoscia, Kraków, Not set

Instytut Centrum Zdrowia Matki Polki, Lodz, Not set

Centrum Medyczne Hope Clinic Sebastian Szklener, Lublin, Not set

Hospital Universitari Vall d Hebron, Barcelona, Cataluña

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña

Hospital Universitario 12 de Octubre, Madrid, Not set

National Cheng Kung University Hospital, Tainan, Not set

Taipei Veterans General Hospital, Taipei, Not set

Adana Sehir Egitim ve Arastirma Hastanesi, Adana, Not set

Ankara Bilkent Sehir Hastanesi, Ankara, Not set

Conditions: Thoracic Tumors, Non-small Cell Lung Cancer

Learn More ›

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT06695845

Recruiting

The purpose of this study is to evaluate the efficacy and safety of zanidatamab for the treatment of participants with previously treated solid tumors that have Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ overexpression.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Arizona Oncology Associates, PC - NAHOA, Prescott, Arizona +20 locations

Conditions: Breast Cancer, Gastric Cancer, Esophageal Cancer, Gastroesophageal Cancer, Colorectal Cancer, Endometrial Cancer, Non-small Cell Lung Cancer, Ovarian Cancer, Urothelial Carcinoma, Salivary Gland Cancer, Pancreatic Cancer, HER-2 Protein Overexpression

Learn More ›

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

NCT01639508

Recruiting

The purpose of this phase II study is to find out what effects cabozantinib (XL184) has, good and/or bad, in patients whose tumors one of the following gene changes RET, ROS1, or NTRK fusion, or increased MET or AXL activity. A phase II study looks at how effective a medication is at treating a specific type of cancer and collects information on the side effects of the study treatment. RET, ROS1, or NTRK fusion or increased MET or AXL activity gene leads to lung cancer cell growth. Cabozantini... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey +6 locations

Conditions: Non-Small Cell Lung Cancer

Learn More ›

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

NCT05211895

Recruiting

This is a Phase III, randomised, double-blind, placebo-controlled, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) and domvanalimab (AB154) compared with durvalumab plus placebo in adults with locally advanced (Stage III), unresectable NSCLC whose disease has not progressed following definitive platinum-based cCRT.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/23/2025

Locations: Research Site, Chandler, Arizona +256 locations

Research Site, Chandler, Arizona

Research Site, Phoenix, Arizona

Research Site, Fountain Valley, California

Research Site, Santa Rosa, California

Research Site, Washington, District of Columbia

Research Site, Jacksonville, Florida

Research Site, Orlando, Florida

Research Site, Saint Augustine, Florida

Research Site, Macon, Georgia

Research Site, Elmhurst, Illinois

Research Site, Maywood, Illinois

Research Site, Naperville, Illinois

Research Site, Louisville, Kentucky

Research Site, Baltimore, Maryland

Research Site, Silver Spring, Maryland

Research Site, Detroit, Michigan

Research Site, Minneapolis, Minnesota

Research Site, Rochester, Minnesota

Research Site, Reno, Nevada

Research Site, East Brunswick, New Jersey

Research Site, Florham Park, New Jersey

Research Site, Buffalo, New York

Research Site, Johnson City, New York

Research Site, Asheville, North Carolina

Research Site, Charlotte, North Carolina

Research Site, Winston-Salem, North Carolina

Research Site, Columbus, Ohio

Research Site, Oklahoma City, Oklahoma

Research Site, Pittsburgh, Pennsylvania

Research Site, Charleston, South Carolina

Research Site, Nashville, Tennessee

Research Site, Fort Sam Houston, Texas

Research Site, Kingwood, Texas

Research Site, Arlington, Virginia

Research Site, Fort Belvoir, Virginia

Research Site, Spokane Valley, Washington

Research Site, Appleton, Wisconsin

Research Site, Brussels, Not set

Research Site, Edegem, Not set

Research Site, Haine-Saint-Paul, Not set

Research Site, Leuven, Not set

Research Site, Liege, Not set

Research Site, Sint-Niklaas, Not set

Research Site, Barretos, Not set

Research Site, Londrina, Not set

Research Site, Porto Alegre, Not set

Research Site, Porto Velho, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Santo Andre, Not set

Research Site, Sao Paulo, Not set

Research Site, São Paulo, Not set

Research Site, Taubaté, Not set

Research Site, Calgary, Alberta

Research Site, Kelowna, British Columbia

Research Site, Laval, Quebec

Research Site, Montreal, Quebec

Research Site, Las Condes, Not set

Research Site, Puerto Montt, Not set

Research Site, Santiago, Not set

Research Site, Temuco, Not set

Research Site, Aix en Provence, Not set

Research Site, Angers, Not set

Research Site, Bobigny, Not set

Research Site, Clermont-Ferrand, Not set

Research Site, Lille, Not set

Research Site, Paris Cedex 14, Not set

Research Site, Pau cedex, Not set

Research Site, Quimper, Not set

Research Site, Saint Gregoire, Not set

Research Site, Saint-Quentin cedex, Not set

Research Site, Vantoux, Not set

Research Site, Villeurbanne, Not set

Research Site, Berlin-Zehlendorf, Not set

Research Site, Berlin, Not set

Research Site, Braunschweig, Not set

Research Site, Chemnitz, Not set

Research Site, Erlangen, Not set

Research Site, Essen, Not set

Research Site, Georgsmarienhuette, Not set

Research Site, Giessen, Not set

Research Site, Halle, Not set

Research Site, Hamburg, Not set

Research Site, Homburg, Not set

Research Site, Koblenz, Not set

Research Site, Krefeld, Not set

Research Site, Köln, Not set

Research Site, Löwenstein, Not set

Research Site, Moers, Not set

Research Site, München, Not set

Research Site, Regensburg, Not set

Research Site, Tübingen, Not set

Research Site, Athens, Not set

Research Site, Holargos, Athens, Not set

Research Site, Thessaloniki, Not set

Research Site, Hong Kong, Not set

Research Site, Budapest, Not set

Research Site, Deszk, Not set

Research Site, Győr, Not set

Research Site, Salgótarján, Not set

Research Site, Székesfehérvár, Not set

Research Site, Törökbálint, Not set

Research Site, Ahmedabad, Not set

Research Site, Bangalore, Not set

Research Site, Delhi, Not set

Research Site, Gurgaon, Not set

Research Site, Howrah, Not set

Research Site, Hyderabad, Not set

Research Site, Jaipur, Not set

Research Site, Kolkata, Not set

Research Site, Marg Jaipur, Not set

Research Site, Mohali, Not set

Research Site, Namakkal, Not set

Research Site, New Delhi, Not set

Research Site, Varanasi, Not set

Research Site, Bergamo, Not set

Research Site, Roma, Not set

Research Site, Rozzano, Not set

Research Site, Udine, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Chiba-shi, Not set

Research Site, Fukuoka-shi, Not set

Research Site, Hidaka-shi, Not set

Research Site, Hirosaki-shi, Not set

Research Site, Itabashi-ku, Not set

Research Site, Kashihara-shi, Not set

Research Site, Koto-ku, Not set

Research Site, Kumamoto-shi, Not set

Research Site, Matsuyama-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Sapporo-shi, Not set

Research Site, Sunto-gun, Not set

Research Site, Tokyo, Not set

Research Site, Yokohama-shi, Not set

Research Site, Daegu, Not set

Research Site, Goyang-si, Not set

Research Site, Incheon, Not set

Research Site, Jinju-si, Not set

Research Site, Seoul, Not set

Research Site, Suwon, Not set

Research Site, Johor Bahru, Not set

Research Site, Kuala Lumpur, Not set

Research Site, Kuching, Not set

Research Site, Selangor, Not set

Research Site, Aguascalientes, Not set

Research Site, Cdmx, Not set

Research Site, Chihuahua, Not set

Research Site, Guadalajara, Not set

Research Site, Monterrey, Not set

Research Site, Oaxaca, Not set

Research Site, San Pedro Garza Garcia, Not set

Research Site, Sonora, Not set

Research Site, Veracruz, Not set

Research Site, Bodø, Not set

Research Site, Gjøvik, Not set

Research Site, Oslo, Not set

Research Site, Trondheim, Not set

Research Site, Bacolod, Not set

Research Site, Iloilo City, Not set

Research Site, Muntinlupa City, Not set

Research Site, Pasig City, Not set

Research Site, Quezon City, Not set

Research Site, Białystok, Not set

Research Site, Gliwice, Not set

Research Site, Katowice, Not set

Research Site, Wroclaw, Not set

Research Site, Zielona Góra, Not set

Research Site, Łódź, Not set

Research Site, Bucuresti, Not set

Research Site, Craiova, Not set

Research Site, Floresti, Not set

Research Site, Iasi, Not set

Research Site, Oradea, Not set

Research Site, Sibiu, Not set

Research Site, Suceava, Not set

Research Site, Timisoara, Not set

Research Site, Amanzimtoti, Not set

Research Site, Cape Town, Not set

Research Site, Johannesburg, Not set

Research Site, Parktown, Not set

Research Site, Pretoria, Not set

Research Site, Bilbao (Vizcaya), Not set

Research Site, Castello de la Plana, Not set

Research Site, Cordoba, Not set

Research Site, El Palmar, Not set

Research Site, Palma de Mallorca, Not set

Research Site, Sabadell (Barcelona), Not set

Research Site, Basel, Not set

Research Site, Bern, Not set

Research Site, Lausanne, Not set

Research Site, Hsinchu, Not set

Research Site, New-Taipei, Not set

Research Site, Taichung, Not set

Research Site, Tainan, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Bangkok, Not set

Research Site, Hat Yai, Not set

Research Site, Adapazari, Not set

Research Site, Ankara, Not set

Research Site, Antalya, Not set

Research Site, Edirne, Not set

Research Site, Istanbul, Not set

Research Site, Izmir, Not set

Research Site, Konya, Not set

Research Site, Çankaya, Not set

Research Site, Birmingham, Not set

Research Site, Brighton, Not set

Research Site, Cambridge, Not set

Research Site, Cardiff, Not set

Research Site, Cheltenham, Not set

Research Site, High Heaton/Newcastle Upon Tyn, Not set

Research Site, Leeds, Not set

Research Site, London, Not set

Research Site, Nottingham, Not set

Research Site, Truro, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh city, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

NCT06685718

Recruiting

This is an open-label, multicenter, Phase 1a/1b clinical study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of BG-60366, a highly potent, selective EGFR-mutation targeted Chimeric Degradation Activation Compound (CDAC). BG-60366 is designed to degrade mutant EGFR, which is a common cause for Non-Small Cell Lung Cancer (NSCLC). This study will evaluate how well BG-60366 works in participants with advanced or metastatic EGFR-mutant NS... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/20/2025

Locations: University of Colorado, Denver, Colorado +42 locations

University of Colorado, Denver, Colorado

University of Miami, Miami, Florida

Dana Farber Cancer Institute, Boston, Massachusetts

Washington University School of Medicine Siteman Cancer Center, Saint Louis, Missouri

Memorial Sloan Kettering Cancer Center Mskcc, New York, New York

Ohio State University, Columbus, Ohio

The University of Texas Md Anderson Cancer Center, Houston, Texas

Blacktown Cancer and Haematology Centre, Blacktown, New South Wales

Liverpool Hospital, Liverpool, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Cancer Research South Australia, Adelaide, South Australia

Austin Health, Heidelberg, Victoria

Peter Maccallum Cancer Centre, Melbourne, Victoria

Fundacao Pio Xii Hospital de Amor de Barretos, Barretos, Not set

Liga Norte Riograndene Contra O Cancer, Natal, Not set

Hospital Sao Lucas Da Pucrs, Porto Alegre, Not set

Hospital Sao Rafael (Rede Dor), Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto, Sao Jose Do Rio Preto, Not set

Icesp Instituto Do Cancer Do Estado de Sao Paulo Octavio Frias de Oliveira, Sao Paulo, Not set

Hospital Israelita Albert Einstein, Sao Paulo, Not set

Hospital Santa Rita de Cassia Afecc, Vitoria, Not set

Beijing Cancer Hospital, Beijing, Beijing

Guangdong Provincial Peoples Hospital Huifu Branch, Guangzhou, Guangdong

The Tumor Hospital Affiliated to Guangxi Medical Universitywuxiang Branch, Nanning, Guangxi

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Shanxi Bethune Hospital, Taiyuan, Shanxi

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin

Sir Run Run Shaw Hospital, Zhejiang University School of Medicineqiantang Branch, Hangzhou, Zhejiang

Irccs Azienda Ospedaliero Universitaria Bologna, Bologna, Not set

Fondazione Irccs San Gerardo Dei Tintori Sc Oncologia, Monza, Not set

Fondazione Policlinico Universitario Agostino Gemelli, Roma, Not set

Chungbuk National University Hospital, SeowonGu CheongjuSi, Chungcheongbukdo

Samsung Medical Center, GangnamGu, Seoul Teugbyeolsi

Severance Hospital Yonsei University Health System, SeodaemunGu, Seoul Teugbyeolsi

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Sarawak General Hospital, Kuching, Not set

Harbour Cancer and Wellness, Auckland, Not set

Hospital Universitario Vall Dhebron, Barcelona, Not set

Hospital Universitario de Octubre, Madrid, Not set

H Puerta de Hierro Majadahonda, Majadahonda, Not set

Ramathibodi Hospital Mahidol University, Dusit, Not set

Songklanagarind Hospital (Prince of Songkhla University), Hat Yai, Not set

Srinagarind Hospital (Khon Kaen University), Muang, Not set

Conditions: Non-Small Cell Lung Cancer, Lung Cancer, NSCLC, NSCLC (Non-small Cell Lung Carcinoma), EGFR Activating Mutation, EGFR Mutation-Related Tumors

Learn More ›

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT06568939

Recruiting

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-small cell lung cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to assess how safe telisotuzumab vedotin is in adult participants with NSCLC. Change in disease activity and adverse events will be assessed. Telisotuzumab vedotin is an investigational drug being developed for the treatment of NSCLC. Participants will be... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/20/2025

Locations: Yale New Haven Hospital /ID# 271584, New Haven, Connecticut +33 locations

Yale New Haven Hospital /ID# 271584, New Haven, Connecticut

Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 270899, Jacksonville, Florida

Ocala Oncology Center /ID# 273697, Ocala, Florida

Comprehensive Hematology Oncology /ID# 270422, Saint Petersburg, Florida

Florida Cancer Specialists - North /ID# 271995, Saint Petersburg, Florida

Florida Cancer Specialists - East /ID# 271993, West Palm Beach, Florida

University Cancer & Blood Center /ID# 270969, Athens, Georgia

Springfield Clinic /ID# 272576, Springfield, Illinois

NHO - Nebraska Hematology-Oncology /ID# 272970, Lincoln, Nebraska

Nebraska Cancer Specialists - Omaha - Wright Street /ID# 271527, Omaha, Nebraska

Astera Cancer Care /ID# 272359, East Brunswick, New Jersey

Clinical Research Alliance - Westbury /ID# 270455, Westbury, New York

FirstHealth of the Carolinas- Speciality Center /ID# 272924, Pinehurst, North Carolina

Mercy Health - Perrysburg Cancer Center /ID# 270536, Perrysburg, Ohio

Genesis Healthcare System /ID# 273361, Zanesville, Ohio

Guthrie Robert Packer Hospital /ID# 270316, Sayre, Pennsylvania

Cancer Care Associates Of York /ID# 270971, York, Pennsylvania

SCRI Oncology Partners /ID# 270162, Nashville, Tennessee

Texas Oncology - Northeast Texas /ID# 272000, Tyler, Texas

Virginia Cancer Specialists - Fairfax /ID# 272004, Fairfax, Virginia

Northwest Medical Specialties Tacoma /ID# 270534, Tacoma, Washington

Beijing Chest Hospital, Capital Medical University /ID# 271935, Beijing, Beijing

Affiliated Cancer Hospital of Guangxi Medical University /ID# 271931, Nanning, Guangxi

Union Hospital - Tongji Medical College /ID# 271668, Wuhan, Hubei

The First Affiliated Hospital of Nanchang University /ID# 271666, Nanchang, Jiangxi

The First Affiliated Hospital of Xi'an Jiaotong University /ID# 271928, Xian, Shaanxi

Linyi Cancer Hospital /ID# 272068, Linyi, Shandong

Cancer Hospital Affliated to Xinjiang Medical University /ID# 271933, Urumqi, Xinjiang

Rambam Health Care Campus /ID# 270078, Haifa, H_efa

Meir Medical Center /ID# 270071, Kfar Saba, HaMerkaz

Shaare Zedek Medical Center /ID# 270095, Jerusalem, Not set

Rabin Medical Center /ID# 270087, Petah Tikva, Not set

National Cancer Centre Singapore /ID# 271499, Singapore, Central Singapore

National University Hospital /ID# 271700, Singapore, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT06236438

Recruiting

Non-Squamous Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer mortality worldwide, with poor survival prospects for metastatic disease. The purpose of this study is to evaluate the optimized dose, adverse events, and efficacy of livmoniplimab in combination with budigalimab plus chemotherapy versus pembrolizumab plus chemotherapy in participants with untreated metastatic non-squamous non-small cell lung cancer. Livmoniplimab is an investigational drug being developed for the treatment of NSCLC. There are 2 stages to this study. In Stage 1, there are 4 treatment arms. Participants will either receive livmoniplimab (at different doses) in combination with budigalimab (another investigational drug) + chemotherapy, budigalimab +chemotherapy, or pembrolizumab +chemotherapy. In Stage 2, there are 2 treatments arms. Participants will either receive livmoniplimab (optimized dose) in combination with budigalimab +chemotherapy or placebo in combination with pembrolizumab +chemotherapy. Chemotherapy consists of IV Infused pemetrexed + IV infused cisplatin or IV infused or injected carboplatin. Approximately 840 adult participants will be enrolled in the study across 200 sites worldwide. Stage 1: In cohort 1, participants will receive intravenously (IV) infused livmoniplimab (dose A)+ IV infused budigalimab, + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + IV Infused pemetrexed. In cohort 2, participants will receive livmoniplimab (dose B) + budigalimab + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + pemetrexed. In cohort 3, participants will receive budigalimab + chemotherapy for 4 cycles followed by budigalimab + pemetrexed . In cohort 4, participants will receive IV Infused pembrolizumab + chemotherapy for 4 cycles followed by pembrolizumab + pemetrexed. Stage 2: In arm 1, participants will receive livmoniplimab (dose optimized) + budigalimab + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + pemetrexed. In arm 2, participants will receive IV Infused placebo + pembrolizumab + chemotherapy for 4 cycles followed by pembrolizumab + pemetrexed. The estimated study duration is 55 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic and may require frequent medical assessments, blood tests, questionnaires, and scans. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/20/2025

Locations: Moores Cancer Center /ID# 267782, La Jolla, California +57 locations

Moores Cancer Center /ID# 267782, La Jolla, California

Memorial Hospital West /ID# 262221, Pembroke Pines, Florida

Bond Clinic /ID# 262611, Winter Haven, Florida

University Cancer & Blood Cent /ID# 261824, Athens, Georgia

The University of Chicago Medical Center /ID# 262259, Chicago, Illinois

University of Kansas Medical Center /ID# 263196, Westwood, Kansas

Baptist Health Lexington /ID# 261823, Lexington, Kentucky

Cancer & Hematology Centers of Western Michigan - East /ID# 261826, Grand Rapids, Michigan

Washington University-School of Medicine /ID# 262759, Saint Louis, Missouri

Stony Brook Cancer Center /ID# 261954, Stony Brook, New York

Cone Health Cancer Center /ID# 262583, Greensboro, North Carolina

Oncology Hematology Care, Inc - Blue Ash /ID# 262733, Cincinnati, Ohio

Guthrie Robert Packer Hospital /ID# 262758, Sayre, Pennsylvania

Renovatio clinical /ID# 262000, El Paso, Texas

Houston Methodist Hospital /ID# 262722, Houston, Texas

Texas Oncology - Plano East /ID# 264356, Plano, Texas

Texas Oncology - San Antonio Medical Center - Research Drive /ID# 264311, San Antonio, Texas

Renovatio Clinical /ID# 261999, The Woodlands, Texas

Vista Oncology - East Olympia /ID# 262303, Olympia, Washington

The Canberra Hospital /ID# 261891, Garran, Australian Capital Territory

Nepean Hospital /ID# 262157, Kingswood, New South Wales

Westmead Hospital /ID# 261894, Westmead, New South Wales

Cliniques Universitaires UCL Saint-Luc /ID# 261267, Bruxelles, Bruxelles-Capitale

Hospital La Louviere Site Jolimont - Helora /ID# 261269, La Louvière, Hainaut

AZ Maria Middelares /ID# 262313, Gent, Not set

Groupe Sante CHC - Clinique du MontLegia /ID# 262338, Liege, Not set

UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 262557, Namur, Not set

Centro de Investigacion y Desarrollo Oncologico /ID# 261800, Temuco, Araucania

Fundacion Arturo Lopez Perez /ID# 261700, Providencia, Region Metropolitana De Santiago

Oncored /Id# 261801, Vitacura, Region Metropolitana Santiago

Sociedad Cem-Cancer Spa /Id# 262316, Viña del Mar, Valparaíso

Hospital Clinico Universidad De Los Andes /ID# 262665, Santiago, Not set

APHM - Hopital Nord /ID# 261129, Marseille, Bouches-du-Rhone

CHU Grenoble - Hopital Michallon /ID# 261131, La Tronche, Isere

Hospices Civils de Lyon (HCL) - Hopital Louis Pradel /ID# 261644, Bron, Rhone

Centre Hosp Intercommunal de Creteil /ID# 261130, Creteil, Val-de-Marne

Rambam Health Care Campus /ID# 262431, Haifa, H_efa

Shaare Zedek Medical Center /ID# 262432, Jerusalem, Yerushalayim

National Cancer Center Hospital East /ID# 261923, Kashiwa-shi, Chiba

Saitama Cancer Center /ID# 262703, Kitaadachi-gun, Saitama

National Cancer Center Hospital /ID# 261925, Chuo-ku, Tokyo

Ziekenhuis St. Jansdal /ID# 261193, Harderwijk, Gelderland

Isala /ID# 262458, Zwolle, Overijssel

Pan American Center for Oncology Trials /ID# 269666, Rio Piedras, Not set

Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 262723, Santiago de Compostela, A Coruna

Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 262118, L'Hospitalet de Llobregat, Barcelona

UOMi Cancer Center - Clinica Tres Torres /ID# 262116, Barcelona, Not set

Hospital Universitario Vall d'Hebron /ID# 262113, Barcelona, Not set

Hospital General Universitario Gregorio Maranon /ID# 262114, Madrid, Not set

Disc_Hospital Universitario 12 de Octubre /ID# 262112, Madrid, Not set

Hospital Clinico Universitario de Valencia /ID# 262115, Valencia, Not set

National Cheng Kung University Hospital /ID# 262016, Tainan, Not set

Mackay Memorial Hospital /ID# 262534, Taipei City, Not set

Taipei Medical University Hospital /ID# 262020, Taipei City, Not set

Linkou Chang Gung Memorial Hospital /ID# 262535, Taoyuan City, Not set

Gazi University Medical Faculty /ID# 261786, Ankara, Not set

Ankara City Hospital /ID# 261785, Ankara, Not set

Dr. Suat Seren Gogus Has /ID# 261789, Izmir, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NCT06422143

Recruiting

This is a phase 3 study of pembrolizumab in combination with carboplatin/taxane (paclitaxel or nab-paclitaxel) followed by pembrolizumab with or without maintenance sacituzumab tirumotecan (sac-TMT; MK-2870) in first-line treatment of metastatic squamous non-small cell lung cancer. It is hypothesized that pembrolizumab with maintenance sacituzumab tirumotecan is superior to pembrolizumab without sacituzumab tirumotecan maintenance with respect to overall survival (OS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/20/2025

Locations: Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0122), Burbank, California +182 locations

Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0122), Burbank, California

Exempla Lutheran Medical Center ( Site 0119), Golden, Colorado

Intermountain Health St. Mary's Regional Hospital ( Site 0116), Grand Junction, Colorado

Mid Florida Hematology and Oncology Center ( Site 0109), Orange City, Florida

Centricity Research Columbus Cancer Center ( Site 0111), Columbus, Georgia

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0001), Marietta, Georgia

University of Chicago Medical Center ( Site 0145), Chicago, Illinois

Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0146), Minneapolis, Minnesota

New Mexico Oncology Hematology Consultants Ltd. ( Site 0123), Albuquerque, New Mexico

Thomas Jefferson University - Clinical Research Institute ( Site 0147), Philadelphia, Pennsylvania

Oncology Consultants P.A. ( Site 0124), Houston, Texas

Mays Cancer Center ( Site 0132), San Antonio, Texas

Instituto Alexander Fleming ( Site 0203), Ciudad Autónoma de Buenos Aires, Buenos Aires

Instituto de Investigaciones Clínicas Mar del Plata ( Site 0200), Mar del Plata, Buenos Aires

Instituto Médico Río Cuarto ( Site 0204), Rio Cuarto., Cordoba

Fundacion Intecnus ( Site 0205), San Carlos de Bariloche, Rio Negro

Sanatorio Parque ( Site 0201), Rosario, Santa Fe

Hospital Aleman-Oncology ( Site 0202), Buenos Aires, Not set

Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0720), Linz, Oberosterreich

Klinik Hietzing ( Site 0740), Wien, Not set

Standort Penzing der Klinik Ottakring-Abteilung für Atemwegs-und Lungenkrankheiten ( Site 0730), Wien, Not set

Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0710), Wien, Not set

Hospital de Câncer de Recife ( Site 0312), Recife, Pernambuco

Oncoclínica Oncologistas Associados ( Site 0309), Terezina, Piaui

Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0311), Porto Alegre, Rio Grande Do Sul

Hospital Nossa Senhora da Conceição ( Site 0300), Porto Alegre, Rio Grande Do Sul

Instituto de Oncologia Saint Gallen ( Site 0304), Santa Cruz do Sul, Rio Grande Do Sul

Hospital de Base de São José do Rio Preto ( Site 0310), São José do Rio Preto, Sao Paulo

Hospital Paulistano ( Site 0307), Sao Paulo, Not set

Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 0100), Kingston, Ontario

Grand River Hospital ( Site 0153), Kitchener, Ontario

St. Marys Hospital Center ( Site 0105), Montreal, Quebec

McGill University Health Centre ( Site 0103), Montréal, Quebec

Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 0106), Trois-Rivières, Quebec

Centro de Investigación del Maule ( Site 0419), Talca, Maule

FALP ( Site 0409), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0402), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 0407), Santiago, Region M. De Santiago

ONCOCENTRO APYS-ACEREY ( Site 0400), Viña del Mar, Valparaiso

Bradford Hill Norte ( Site 0420), Antofagasta, Not set

Beijing Cancer Hospital ( Site 2411), Beijing, Beijing

Beijing Cancer hospital-intrathoratic deparmtment II ( Site 2410), Beijing, Beijing

Peking Union Medical College Hospital ( Site 2412), Beijing, Beijing

Army Medical Center of People's Liberation Army-respiratory ( Site 2426), Chongqing, Chongqing

Fujian Provincial Cancer Hospital ( Site 2419), Fuzhou, Fujian

The First Affiliated hospital of Xiamen University-oncology ( Site 2420), Xiamen, Fujian

The First Affiliated Hospital of Guangzhou Medical University ( Site 2417), Guangzhou, Guangdong

Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2416), Guangzhou, Guangdong

Harbin Medical University Cancer Hospital-oncology of department ( Site 2415), Harbin, Heilongjiang

Henan Cancer Hospital-Pneumology department ( Site 2423), Zhengzhou, Henan

Tongji Hospital Tongji Medical,Science & Technology ( Site 2424), Wuhan, Hubei

The Second Xiangya Hospital of Central South University-Oncology ( Site 2418), Changsha, Hunan

First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 2402), Huai'an, Jiangsu

Northern Jiangsu People's Hospital-General Surgery Department ( Site 2403), Yangzhou, Jiangsu

The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2405), Nanchang, Jiangxi

The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 2404), Nanchang, Jiangxi

Jilin Province Tumor Hospital-GCP office ( Site 2413), Changchun, Jilin

The First Hospital of Jilin University-Oncology ( Site 2414), Changchun, Jilin

Shanghai East Hospital ( Site 2428), Shanghai, Shanghai

Shanghai Pulmonary Hospital ( Site 2427), Shanghai, Shanghai

West China Hospital, Sichuan University ( Site 2422), Cheng Du, Sichuan

Sichuan Cancer hospital. ( Site 2421), Chengdu, Sichuan

The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 2425), Urumqi, Xinjiang

The first Affiliated Hospital, Zhejiang University School of Medicine-Respiratory Department ( Site 2406), Hangzhou, Zhejiang

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 2407), Hangzhou, Zhejiang

Zhejiang Cancer Hospital-Breast Oncology ( Site 2408), Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province ( Site 2430), Taizhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 2409), Wenzhou, Zhejiang

Centro Cancerológico del Caribe (CECAC) ( Site 0509), Barranquilla, Atlantico

Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar

FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0500), Bogota, Distrito Capital De Bogota

Oncologos del Occidente ( Site 0504), Pereira., Risaralda

Fundación Valle del Lili-Oncology CIC ( Site 0505), Cali, Valle Del Cauca

Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0800), Brno, Brno-mesto

Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni oddeleni ( Site 0803), Ostrava-Vitkovice, Ostrava Mesto

Clinique Clairval ( Site 0904), Marseille, Bouches-du-Rhone

Hôpital Robert Schuman ( Site 0907), Vantoux, Lorraine

Institut de Cancérologie de l'Ouest ( Site 0908), ANGERS cedex 02, Maine-et-Loire

Sainte Catherine Institut du Cancer Avignon Provence ( Site 0902), Avignon, Vaucluse

CHD Vendee ( Site 0901), La Roche-sur-Yon, Vendee

Hôpital Saint-Louis ( Site 0906), Paris, Not set

GEFOS Gesellschaft f. onkologische Studien ( Site 1005), Dortmund, Nordrhein-Westfalen

SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1006), Gera, Thuringen

Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 1003), Berlin, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz ( Site 1100), Kecskemét, Bacs-Kiskun

Petz Aladar Egyetemi Oktato Korhaz ( Site 1101), Gyor, Gyor-Moson-Sopron

Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 1103), Szolnok, Jasz-Nagykun-Szolnok

Reformatus Pulmonologiai Centrum ( Site 1102), Torokbalint, Pest

Zala Megyei Szent Rafael Kórház ( Site 1110), Zalaegerszeg, Zala

Országos Korányi Pulmonológiai Intézet ( Site 1104), Budapest, Not set

St. James's Hospital ( Site 1200), Dublin, Not set

Rambam Health Care Campus-Oncology Division ( Site 1302), Haifa, Not set

Shaare Zedek Medical Center ( Site 1300), Jerusalem, Not set

Rabin Medical Center ( Site 1303), Petah Tikva, Not set

Sheba Medical Center ( Site 1301), Ramat Gan, Not set

Istituto Nazionale Tumori IRCCS Fondazione Pascale-Oncologia clinica sperimentale Toraco-Polmonare ( Site 1401), Napoli, Campania

Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 1409), Roma, Lazio

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1404), Milan, Lombardia

Fondazione IRCCS San Gerardo dei Tintori-Oncologia ( Site 1412), Monza, Lombardia

Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1408), Rozzano, Milano

Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1402), Rome, Roma

Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1414), Brescia, Not set

Ospedale San Martino ( Site 1407), Genova, Not set

Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 1410), Pavia, Not set

Ospedale di Circolo e Fondazione Macchi Varese-Oncology ( Site 1413), Varese, Not set

Aichi Cancer Center ( Site 2502), Nagoya, Aichi

Nagoya University Hospital ( Site 2519), Nagoya, Aichi

Fujita Health University Hospital ( Site 2515), Toyoake, Aichi

Hirosaki University Hospital ( Site 2514), Hirosaki, Aomori

Ehime University Hospital ( Site 2511), Toon, Ehime

Gunma Prefectural Cancer Center ( Site 2510), Ota, Gunma

Takarazuka City Hospital ( Site 2508), Takarazuka, Hyogo

Kanazawa University Hospital ( Site 2513), Kanazawa, Ishikawa

St. Marianna University Hospital ( Site 2521), Kawasaki, Kanagawa

Kanagawa Cardiovascular and Respiratory Center ( Site 2518), Yokohama, Kanagawa

Kanagawa Cancer Center ( Site 2504), Yokohama, Kanagawa

Matsusaka Municipal Hospital ( Site 2522), Matsusaka, Mie

Sendai Kousei Hospital ( Site 2507), Sendai, Miyagi

Kansai Medical University Hospital ( Site 2503), Hirakata, Osaka

Saitama Prefectural Cancer Center ( Site 2512), Kitaadachi-gun, Saitama

Cancer Institute Hospital of JFCR ( Site 2500), Koto, Tokyo

Toho University Omori Medical Center ( Site 2520), Ota, Tokyo

National Center for Global Health and Medicine ( Site 2516), Shinjuku, Tokyo

Chiba University Hospital ( Site 2517), Chiba, Not set

National Hospital Organization Kyushu Medical Center ( Site 2509), Fukuoka, Not set

Niigata Cancer Center Hospital ( Site 2505), Niigata, Not set

Osaka International Cancer Institute ( Site 2506), Osaka, Not set

The Catholic University of Korea, Incheon St. Mary's Hospital ( Site 2106), Bupyeong-gu, Incheon

Pusan National University Yangsan Hospital ( Site 2104), Yangsan-si, Kyongsangnam-do

Pusan National University Hospital ( Site 2100), Busan, Pusan-Kwangyokshi

Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2102), Deagu, Taegu-Kwangyokshi

Chungnam national university hospital-Department of Internal Medicine ( Site 2107), Daejeon, Taejon-Kwangyokshi

Kyung Hee University Hospital ( Site 2101), Seoul, Not set

Asan Medical Center ( Site 2105), Seoul, Not set

Korea University Guro Hospital-Internal Medicine ( Site 2103), Seoul, Not set

Clínicas AUNA Sede Chiclayo ( Site 0604), Chiclayo, Lambayeque

Oncosalud-Clinical Research ( Site 0600), Lima, Not set

Hospital Militar Central Coronel Luis Arias Schereiber ( Site 0602), Lima, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 1510), Poznań, Dolnoslaskie

Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1503), Bydgoszcz, Kujawsko-pomorskie

Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1513), Grudziadz, Kujawsko-pomorskie

Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1515), Kraków, Malopolskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 1500), Warszawa, Mazowieckie

Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1501), Przemysl, Podkarpackie

Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1517), Koszalin, Zachodniopomorskie

Centrul Medical Medicover Victoria ( Site 2000), Bucharest, Bucuresti

Cardiomed SRL Cluj-Napoca ( Site 2002), Cluj-Napoca, Cluj

SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 2001), Florești, Cluj

Centrul de Oncologie Sfantul Nectarie-Medical ( Site 2004), Craiova, Dolj

Cabinet Medical Oncomed ( Site 2005), Timisoara, Timis

SC ONCO CARD SRL ( Site 2007), Brasov, Not set

Clinica Polisano ( Site 2008), Sibiu, Not set

CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 1703), Santiago de Compostela, Galicia

Hospital Insular de Gran Canaria-Oncology ( Site 1701), Las Palmas de Gran Canaria, Las Palmas

Hospital Quirón Málaga ( Site 1704), Málaga, Malaga

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1700), Barcelona, Not set

Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 1702), Madrid, Not set

Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 1705), Sevilla, Not set

Chang Gung Memorial Hospital at Kaohsiung ( Site 2207), Kaohsiung Niao Sung Dist, Kaohsiung

National Taiwan University Cancer Center (NTUCC) ( Site 2209), Taipei City, Taipei

Taoyuan General Hospital ( Site 2203), Taoyuan City, Taoyuan

Taichung Veterans General Hospital ( Site 2204), Taichung, Not set

National Cheng Kung University Hospital ( Site 2205), Tainan, Not set

National Taiwan University Hospital-Oncology ( Site 2208), Taipei, Not set

Mackay Memorial Hospital-Chest Medicine ( Site 2201), Taipei, Not set

Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 2202), Taoyuan, Not set

Prapokklao Hospital ( Site 2306), Mueang, Chanthaburi

Faculty of Medicine - Khon Kaen University ( Site 2305), Muang, Khon Kaen

Faculty of Medicine Siriraj Hospital ( Site 2301), Bangkok, Krung Thep Maha Nakhon

Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 2300), Dusit, Krung Thep Maha Nakhon

Lampang Cancer Hospital ( Site 2304), Mueang Lampang, Lampang

Songklanagarind hospital ( Site 2303), HatYai, Songkhla

Maharaj Nakorn Chiang Mai Hospital ( Site 2302), Chiang Mai, Not set

Medipol Mega Universite Hastanesi-oncology ( Site 1811), Stanbul, Istanbul

Hacettepe Universite Hastaneleri-oncology hospital ( Site 1801), Ankara, Not set

Gazi Universitesi-Oncology ( Site 1804), Ankara, Not set

Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1800), Ankara, Not set

Memorial Kayseri Hastanesi ( Site 1805), Kayseri, Not set

Mersin Sehir Eğitim ve Araştırma Hastanesi-Oncology ( Site 1808), Mersin, Not set

Samsun Medical Park Hastanesi-medical oncology ( Site 1806), Samsun, Not set

Burjeel Medical City ( Site 2600), Abu Dhabi, Abu Zaby

St Bartholomew's Hospital ( Site 1901), London, London, City Of

City Hospital, Nottingham University Hospitals NHS Trust-NCCTT ( Site 1911), Nottingham, Nottinghamshire

Conditions: Non-small Cell Lung Cancer, NSCLC

Learn More ›

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

NCT06077760

Recruiting

The goal of this study is to evaluate intismeran autogene plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of margin negative, completely resected Stage II, IIIA, IIIB (with nodal involvement \[N2\]) non-small cell lung cancer (NSCLC). The primary hypothesis is that intismeran autogene plus pembrolizumab is superior to placebo plus pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/19/2025

Locations: Alaska Oncology and Hematology ( Site 0039), Anchorage, Alaska +193 locations

Alaska Oncology and Hematology ( Site 0039), Anchorage, Alaska

The University of Arizona Cancer Center - North Campus ( Site 0071), Tucson, Arizona

YUMA REGIONAL MEDICAL CENTER CANCER CENTER ( Site 0020), Yuma, Arizona

UCLA Clinical & Translational Research Center (CTRC) ( Site 0059), Los Angeles, California

St. Joseph Hospital-The Center for Cancer Prevention and Treatment ( Site 0074), Orange, California

University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0030), Orange, California

UCHealth Memorial Hospital-Heme Onc ( Site 0052), Colorado Springs, Colorado

Mid Florida Hematology and Oncology Center ( Site 0014), Orange City, Florida

AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlandoc ( Site 0013), Orlando, Florida

Moffitt Cancer Center ( Site 0078), Tampa, Florida

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0012), Marietta, Georgia

Southeastern Regional Medical Center ( Site 0098), Newnan, Georgia

Beacon Cancer Care ( Site 0044), Post Falls, Idaho

University of Iowa-Holden Comprehensive Cancer Center ( Site 0062), Iowa City, Iowa

Saint Elizabeth Healthcare ( Site 0092), Edgewood, Kentucky

The University of Louisville, James Graham Brown Cancer Center ( Site 0037), Louisville, Kentucky

University of Michigan Clinical Trials Office ( Site 0058), Ann Arbor, Michigan

Cancer and Hematology Centers of Western Michigan ( Site 4003), Grand Rapids, Michigan

St. Vincent Frontier Cancer Center ( Site 0043), Billings, Montana

NHO Revive Research Institute, LLC ( Site 4009), Lincoln, Nebraska

John Theurer Cancer Center at Hackensack University Medical Center ( Site 0036), Hackensack, New Jersey

New York Oncology Hematology, P.C. ( Site 4012), Albany, New York

Montefiore Medical Center- Montefiore Medical Park-Oncology ( Site 0080), Bronx, New York

Perlmutter Cancer Center at NYU Langone Hospital - Long Island-Clinical Research Department ( Site 0095), Mineola, New York

Laura and Isaac Perlmutter Cancer Center ( Site 0010), New York, New York

Icahn School of Medicine at Mount Sinai ( Site 0034), New York, New York

Columbia University Irving Medical Center-CUIMC Herbert Irving Comprehensive Cancer Center Clinical ( Site 0054), New York, New York

Memorial Sloan Kettering Cancer Center ( Site 0029), New York, New York

Stony Brook University-Cancer Center ( Site 0072), Stony Brook, New York

Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 0063), Fargo, North Dakota

Altru Health System ( Site 0040), Grand Forks, North Dakota

Summa Health ( Site 4011), Akron, Ohio

University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 0028), Cincinnati, Ohio

University Hospitals Cleveland Medical Center ( Site 0023), Cleveland, Ohio

OSU Brain and Spine Hospital ( Site 0016), Columbus, Ohio

Good Samaritan Regional Medical Center-Samaritan Pastega Regional Cancer Center ( Site 0082), Corvallis, Oregon

Thomas Jefferson University - Clinical Research Institute ( Site 0006), Philadelphia, Pennsylvania

Medical University of South Carolina-Hollings Cancer Center ( Site 0050), Charleston, South Carolina

Sanford Cancer Center ( Site 0075), Sioux Falls, South Dakota

Thompson Cancer Survival Center ( Site 0097), Knoxville, Tennessee

One Oncology - Tennessee Oncology ( Site 4019), Nashville, Tennessee

SCRI Oncology Partners ( Site 7001), Nashville, Tennessee

UT Southwestern Medical Center ( Site 0061), Dallas, Texas

Inova Schar Cancer Institute ( Site 0003), Fairfax, Virginia

Swedish Medical Center-Swedish Cancer Institute ( Site 0088), Seattle, Washington

Edwards Comprehensive Cancer Center ( Site 4015), Huntington, West Virginia

Clinica Adventista Belgrano-Oncology ( Site 2901), Caba., Buenos Aires

Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 2912), Caba, Buenos Aires

Instituto Alexander Fleming ( Site 2911), Ciudad Autónoma de Buenos Aires, Buenos Aires

Instituto de Investigaciones Clínicas Mar del Plata ( Site 2908), Mar del Plata, Buenos Aires

Fundacion Estudios Clinicos-Oncology ( Site 2907), Rosario, Santa Fe

Sanatorio Parque ( Site 2904), Rosario, Santa Fe

Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0203), Melbourne, Victoria

St Vincent's Hospital-Oncology Clinical Trials ( Site 0202), Melbourne, Victoria

One Clinical Research ( Site 0200), Nedlands, Western Australia

Antwerp University Hospital-Thoracic Oncology ( Site 0603), Edegem, Antwerpen

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi ( Site 0602), Yvoir, Namur

AZORG Campus Aalst-Moorselbaan ( Site 0604), Aalst, Oost-Vlaanderen

VITAZ ( Site 0600), Sint-Niklaas, Oost-Vlaanderen

CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA-Pesquisa Clínica ( Site 3007), Fortaleza, Ceara

Liga Norte Riograndense Contra o Câncer ( Site 3001), Natal., Rio Grande Do Norte

Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 3003), Porto Alegre, Rio Grande Do Sul

Hospital Nossa Senhora da Conceição ( Site 3002), Porto Alegre, Rio Grande Do Sul

Fundação Pio XII - Hospital de Câncer de Barretos ( Site 3004), Barretos, Sao Paulo

Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 3013), São José do Rio Preto, Sao Paulo

Instituto Nacional de Câncer - INCA ( Site 3000), Rio de Janeiro, Not set

Hospital Samaritano De Sao Paulo ( Site 3006), Sao Paulo, Not set

ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 3005), Sao Paulo, Not set

Cross Cancer Institute ( Site 0105), Edmonton, Alberta

William Osler Health System ( Site 0101), Brampton, Ontario

Princess Margaret Cancer Centre ( Site 0102), Toronto, Ontario

Centre Hospitalier de l'Université de Montréal ( Site 0104), Montréal, Quebec

McGill University Health Centre ( Site 0100), Montréal, Quebec

Orlandi Oncologia-Oncology ( Site 3102), Santiago, Region M. De Santiago

FALP-UIDO ( Site 3100), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile-Centro del Cáncer ( Site 3104), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 3103), Santiago, Region M. De Santiago

ONCOCENTRO APYS ( Site 3105), Viña del Mar, Valparaiso

CIMCA ( Site 3300), San José, San Jose

ICIMED ( Site 3301), San Jose, Not set

Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0700), Brno, Brno-mesto

Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni odd ( Site 0702), Ostrava, Ostrava Mesto

Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 0701), Olomouc, Not set

Vseobecna fakultni nemocnice v Praze ( Site 0703), Praha 2, Not set

Rigshospitalet ( Site 0801), Copenhagen, Hovedstaden

Odense Universitetshospital ( Site 0800), Odense C, Syddanmark

North Estonia Medical Centre Foundation-Chemotherapy ( Site 0901), Tallinn, Harjumaa

Tartu University Hospital-Radiotherapy and oncology ( Site 0900), Tartu, Tartumaa

Tampereen yliopistollinen sairaala-Oncology ( Site 1001), Tampere, Pirkanmaa

Vaasan Keskussairaala-Department of Clinical Oncology ( Site 1004), Vaasa, Pohjanmaa

Oulun yliopistollinen sairaala-Oncology and Hematology ( Site 1003), Oulu, Pohjois-Pohjanmaa

Turku University Hospital-The Department of Pulmonary Medicine ( Site 1000), Turku, Varsinais-Suomi

Nouvel Hôpital Civil (NHC)-Service de pneumologie ( Site 1100), Strasbourg, Alsace

CHU Bordeaux Haut-Leveque ( Site 1106), Pessac, Aquitaine

Assistance Publique Hôpitaux de Marseille - Hôpital Nord ( Site 1108), Marseille, Bouches-du-Rhone

Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre ( Site 1107), Caen, Calvados

Hôpital Arnaud de Villeneuve - CHU Montpellier ( Site 1102), Montpellier, Herault

Institut de Cancérologie de l'Ouest ( Site 1101), ANGERS cedex 02, Maine-et-Loire

CHU GABRIEL MONTPIED ( Site 1105), Clermont-Ferrand, Puy-de-Dome

Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 1104), Paris, Not set

Klinikum Esslingen-Klinik für Kardiologie und Pneumologie ( Site 1201), Esslingen, Baden-Wurttemberg

Asklepios Klinik Gauting GmbH-Oncology ( Site 1209), Gauting, Bayern

Klinikverbund Allgäu gGmbH ( Site 1205), Kempten, Bayern

Universitaetsklinikum Regensburg ( Site 1204), Regensburg, Bayern

Augusta-Kranken-Anstalt ( Site 1213), Bochum, Nordrhein-Westfalen

Gemeinschaftspraxis für Hämatologie und Onkologie Münster ( Site 1202), Münster, Nordrhein-Westfalen

Brüderkrankenhaus St. Josef Paderborn-Klinik für Hämatologie und Onkologie ( Site 1214), Paderborn, Nordrhein-Westfalen

SRH Wald-Klinikum Gera-Lungenkrebszentrum ( Site 1200), Gera, Thuringen

Helios Klinikum Emil von Behring Berlin-Zehlendorf-Lungenklinik Heckeshorn ( Site 1208), Berlin, Not set

Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 1301), Athens, Attiki

THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 1300), Athens, Attiki

European Interbalkan Medical Center-Oncology Department ( Site 1302), Thessaloniki, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 1401), Kecskemét, Bacs-Kiskun

Pécsi Tudományegyetem Klinikai Központ-Onkoterápiás Intézet ( Site 1402), Pecs, Baranya

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz - Pulmonologia Osztaly ( Site 1404), Gyor, Gyor-Moson-Sopron

Reformatus Pulmonologiai Centrum ( Site 1405), Törökbálint, Pest

Somogy Varmegyei Kaposi Mor Oktato Korhaz -Onkologiai Kozpont ( Site 1407), Kaposvár, Somogy

Tallaght University Hospital ( Site 3903), Dublin, Not set

CRO-IRCCS-Clinical Oncology ( Site 1510), Aviano, Friuli-Venezia Giulia

P.O. "S. Maria della Misericordia" Azienda Sanitaria Univers-Oncology Department ( Site 1506), Udine, Friuli-Venezia Giulia

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1504), Milan, Lombardia

ASST Grande Ospedale Metropolitano Niguarda-Oncologia Falck ( Site 1511), Milan, Milano

A.O.R.N. Ospedale dei Colli - Monaldi V.-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 1508), Naples, Napoli

Instituto Tumori Giovanni Paolo II-SSD Oncologia Medica per la Patologia Toracica ( Site 1507), Bari, Puglia

POLICLINICO "G. RODOLICO"-UOC Oncologia Medica ( Site 1503), Catania, Sicilia

AO Santa Maria della Misericordia-Oncology Department ( Site 1501), Perugia, Umbria

Azienda Ospedaliera Santa Croce e Carle ( Site 1500), Cuneo, Not set

Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 1502), Novara, Not set

St. Marianna University Hospital ( Site 3802), Kawasaki, Kanagawa

Kanagawa Cancer Center ( Site 3801), Yokohama, Kanagawa

Kindai University Hospital ( Site 3803), Osakasayama, Osaka

Hiroshima University Hospital ( Site 3804), Hiroshima, Not set

Chungbuk National University Hospital-Internal medicine ( Site 0402), Cheongju-si, Chungbuk

National Cancer Center-Lung Cancer Center ( Site 0403), Goyang-si, Kyonggi-do

Seoul National University Bundang Hospital-Medical Oncology ( Site 0404), Seongnam, Kyonggi-do

The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 0406), Suwon-si, Kyonggi-do

Keimyung University Dongsan Hospital CRC room 1 ( Site 0407), Daegu, Taegu-Kwangyokshi

Seoul National University Hospital ( Site 0400), Seoul, Not set

Asan Medical Center-Department of Oncology ( Site 0405), Seoul, Not set

Samsung Medical Center ( Site 0401), Seoul, Not set

RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia ( Site 1600), Riga, Not set

Hospital of Lithuanian University of Health Sciences Kauno klinikos-Pulmonology ( Site 1701), Kaunas, Kauno Apskritis

National Cancer Institute-Department of Thoracic Surgery and Oncology ( Site 1700), Vilnius, Vilniaus Miestas

University Malaya Medical Centre ( Site 3502), Lembah Pantai, Kuala Lumpur

National Cancer Institute-Radiotherapy and Oncology ( Site 3506), Putrajaya, Kuala Lumpur

Hospital Tengku Ampuan Afzan ( Site 3504), Kuantan, Pahang

Hospital Pulau Pinang ( Site 3505), George Town, Pulau Pinang

Sarawak General Hospital ( Site 3500), Kuching, Sarawak

CIO - Centro de Inmuno-Oncología de Occidente ( Site 3403), Guadalajara, Jalisco

Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 3408), Monterrey, Nuevo Leon

Unidad de Mastologia Avanzada de Chihuahua S.A de C.V ( Site 3402), Chihuahua, Not set

Mediadvance Clinical ( Site 3404), Chihuahua, Not set

Oaxaca Site Management Organization S.C. ( Site 3407), Oaxaca, Not set

Centro de Investigacion Clinica de Oaxaca ( Site 3401), Oaxaca, Not set

New Zealand Clinical Research (Christchurch) ( Site 0300), Christchurch, Canterbury

Harbour Cancer & Wellness ( Site 0301), Auckland, Not set

Akershus Universitetssykehus-Avdeling for lungesykdommer ( Site 1900), Lørenskog, Akershus

Drammen Sykehus, Vestre Viken HF ( Site 1903), Drammen, Buskerud

Stavanger Universitetssykehus ( Site 1901), Stavanger, Rogaland

Metro Davao Medical and Research Center ( Site 3602), Davao City, Davao Del Sur

ST. LUKE'S MEDICAL CENTER ( Site 3606), Quezon City, National Capital Region

CARDINAL SANTOS MEDICAL CENTER-Research Room ( Site 3601), San Juan City, Metro Manila, National Capital Region

Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kujawsko-pomorskie

Krakowski Szpital Specjalistyczny im. Jana Pawła II-Oddział Kliniczny Chirurgii Klatki Piersiowej i ( Site 2011), Krakow, Malopolskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warszawa, Mazowieckie

Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001), Przemysl, Podkarpackie

Bialostockie Centrum Onkologii ( Site 2005), Bialystok, Podlaskie

Uniwersyteckie Centrum Kliniczne ( Site 2013), Gdansk, Pomorskie

Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie-Oddzial Onkologii z Pododdzialem Chemioterapii ( Site 2008), Olsztyn, Warminsko-mazurskie

Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 2002), Poznan, Wielkopolskie

Unidade Local de Saude de Santa Maria - Hospital Pulido Valente ( Site 2703), Lisbon, Lisboa

Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 2702), Porto, Not set

Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica ( Site 2202), Banska Bystrica, Banskobystricky Kraj

Univerzitná nemocnica Bratislava - Nemocnica Ružinov ( Site 2201), Bratislava, Bratislavsky Kraj

Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 2401), L'Hospitalet de Llobregat, Barcelona

HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA-Medical Oncology ( Site 2403), Majadahonda, Madrid, Comunidad De

HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2402), Pozuelo de Alarcon, Madrid

Hospital Quirón Málaga ( Site 2405), Málaga, Malaga

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2400), Barcelona, Not set

Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 2404), Sevilla, Not set

National Taiwan University Cancer Center (NTUCC) ( Site 0500), Taipei City, Taipei

Changhua Christian Hospital ( Site 0504), Changhua, Not set

National Taiwan University Hospital - Hsinchu branch ( Site 0501), Hsinchu, Not set

Taichung Veterans General Hospital-Chest ( Site 0503), Taichung, Not set

National Cheng Kung University Hospital-Clinical Trial Center ( Site 0505), Tainan, Not set

National Taiwan University Hospital-Oncology ( Site 0506), Taipei, Not set

Taipei Medical University Hospital ( Site 0502), Taipei, Not set

Medipol Mega Universite Hastanesi-oncology ( Site 2105), Stanbul, Istanbul

Ege Universitesi Hastanesi-Chest Diseases Department ( Site 2107), Bornova, Izmir

Hacettepe Universite Hastaneleri-oncology hospital ( Site 2100), Ankara, Not set

Memorial Ankara Hastanesi-Medical Oncology ( Site 2103), Ankara, Not set

Liv Hospital Ankara-Oncology ( Site 2104), Ankara, Not set

Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 2101), Ankara, Not set

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2102), Istanbul, Not set

Conditions: Non-small Cell Lung Cancer

Learn More ›

A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation

NCT05789082

Recruiting

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and activity of divarasib combined with other anti-cancer therapies in participants with previously untreated, advanced or metastatic non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/19/2025

Locations: City of Hope National Medical Center, Duarte, California +64 locations

City of Hope National Medical Center, Duarte, California

City of Hope - Seacliff, Huntington Beach, California

City of Hope at Irvine Lennar, Irvine, California

UCSD Moores Cancer Center, La Jolla, California

Yale Cancer Center, New Haven, Connecticut

NYU Langone Hospital - Long Island, Mineola, New York

NYU Cancer Center, New York, New York

Mount SInai Medical Center, New York, New York

MD Anderson Cancer Center, Houston, Texas

Oncology & Hematology Associates of Southwest Virginia, Inc, Blacksburg, Virginia

Virginia Oncology Associates, Norfolk, Virginia

Hospital Britanico, Buenos Aires, Not set

Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires, Not set

Centro Oncologico Riojano Integral (CORI), La Rioja, Not set

Concord Repatriation General Hospital, Concord, New South Wales

Peter MacCallum Cancer Centre, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

Cliniques Universitaires St-Luc, Bruxelles, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

Clinique Ste-Elisabeth, Namur, Not set

AZ Delta (Campus Rumbeke), Roeselare, Not set

Hospital de Cancer de Barretos, Barretos, São Paulo

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo

Ottawa Hospital Regional Cancer Centre, Ottawa, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

Hunan Cancer Hospital, Changsha CITY, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Shanghai Pulmonary Hospital, Shanghai, Not set

Rambam Medical Center, Haifa, Not set

Rabin MC, Petach Tikva, Not set

Tel Aviv Sourasky Medical Ctr, Tel Aviv, Not set

Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania

Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio

Irccs Istituto Nazionale Dei Tumori (Int), Milano, Lombardia

A.O. Universitaria S. Luigi Gonzaga, Orbassano, Piemonte

National Cancer Center Hospital East, Chiba, Not set

National Cancer Center Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Wakayama Medical University Hospital, Wakayama, Not set

Pusan National University Hospital, Busan, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

NKI The Netherlands Cancer Institute, Amsterdam, Not set

UMC St Radboud, Nijmegen, Not set

Uniwersyteckie Centrum Kliniczne, Gda?sk, Not set

Krakowski Szpital Specjalistyczny im sw. Jana Paw?a II, Kraków, Not set

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie, Olsztyn, Not set

ICO Badalona-H.U. Germans Trias i Pujol, Badalona, Barcelona

Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Sahlgrenska University Hospital, Göteborg, Not set

Universitätsspital Basel, Basel, Not set

Inselspital Bern, Bern, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan Uni Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

Barts & London School of Med, London, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

Browse by State

Non-Small Cell Lung Cancer clinical trials in Alabama

Non-Small Cell Lung Cancer clinical trials in Alaska

Non-Small Cell Lung Cancer clinical trials in Arizona

Non-Small Cell Lung Cancer clinical trials in Arkansas

Non-Small Cell Lung Cancer clinical trials in California

Non-Small Cell Lung Cancer clinical trials in Colorado

Non-Small Cell Lung Cancer clinical trials in Connecticut

Non-Small Cell Lung Cancer clinical trials in Delaware

Non-Small Cell Lung Cancer clinical trials in District of Columbia

Non-Small Cell Lung Cancer clinical trials in Florida

Non-Small Cell Lung Cancer clinical trials in Georgia

Non-Small Cell Lung Cancer clinical trials in Hawaii

Non-Small Cell Lung Cancer clinical trials in Idaho

Non-Small Cell Lung Cancer clinical trials in Illinois

Non-Small Cell Lung Cancer clinical trials in Indiana

Non-Small Cell Lung Cancer clinical trials in Iowa

Non-Small Cell Lung Cancer clinical trials in Kansas

Non-Small Cell Lung Cancer clinical trials in Kentucky

Non-Small Cell Lung Cancer clinical trials in Louisiana

Non-Small Cell Lung Cancer clinical trials in Maine

Non-Small Cell Lung Cancer clinical trials in Montana

Non-Small Cell Lung Cancer clinical trials in Nebraska

Non-Small Cell Lung Cancer clinical trials in Nevada

Non-Small Cell Lung Cancer clinical trials in New Hampshire

Non-Small Cell Lung Cancer clinical trials in New Jersey

Non-Small Cell Lung Cancer clinical trials in New Mexico

Non-Small Cell Lung Cancer clinical trials in New York

Non-Small Cell Lung Cancer clinical trials in North Carolina

Non-Small Cell Lung Cancer clinical trials in North Dakota

Non-Small Cell Lung Cancer clinical trials in Ohio

Non-Small Cell Lung Cancer clinical trials in Oklahoma

Non-Small Cell Lung Cancer clinical trials in Oregon

Non-Small Cell Lung Cancer clinical trials in Maryland

Non-Small Cell Lung Cancer clinical trials in Massachusetts

Non-Small Cell Lung Cancer clinical trials in Michigan

Non-Small Cell Lung Cancer clinical trials in Minnesota

Non-Small Cell Lung Cancer clinical trials in Mississippi

Non-Small Cell Lung Cancer clinical trials in Missouri

Non-Small Cell Lung Cancer clinical trials in Pennsylvania

Non-Small Cell Lung Cancer clinical trials in Rhode Island

Non-Small Cell Lung Cancer clinical trials in South Carolina

Non-Small Cell Lung Cancer clinical trials in South Dakota

Non-Small Cell Lung Cancer clinical trials in Tennessee

Non-Small Cell Lung Cancer clinical trials in Texas

Non-Small Cell Lung Cancer clinical trials in Utah

Non-Small Cell Lung Cancer clinical trials in Vermont

Non-Small Cell Lung Cancer clinical trials in Virginia

Non-Small Cell Lung Cancer clinical trials in Washington

Non-Small Cell Lung Cancer clinical trials in West Virginia

Non-Small Cell Lung Cancer clinical trials in Wisconsin

Non-Small Cell Lung Cancer clinical trials in Wyoming