There are currently 684 clinical trials in Orlando, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including AdventHealth Orlando, GSK Investigational Site, Orlando Clinical Research Center and Nemours Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Influence of Oral Contraceptives During Disuse
NCT06275048
Recruiting
Studies across various sports and physical activities have consistently shown that females incur more injuries compared to their male counterparts, but the underlying reasons for this disparity remain poorly understood. While differences in hormone levels between males and females have been speculated to play a role, very little rigorous research has been conducted to directly examine potential connections between sex hormones and injury risk. Specifically, females have been shown to be at great... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
02/16/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Oral Contraceptives, Rehabilitation, Menstrual Cycle, Physical Therapy
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Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections
NCT06179459
Recruiting
Acute pancreatitis is one of the most common gastrointestinal disorders requiring hospitalization worldwide. Pancreatic fluid collections can occur as a consequence of acute and chronic pancreatitis and can result in significant morbidity and mortality, including significant abdominal pain, gastric outlet obstruction, biliary obstruction, organ failure, persistent unwellness, infection and sepsis. Symptomatic pancreatic fluid collections require treatment, and endoscopic drainage is considered... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Acute Pancreatitis, Pancreatic Pseudocyst, Pancreatic Necrosis
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Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts
NCT05572788
Recruiting
The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered rectally, during EUS-FNA.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Pancreatic Cyst, Pancreatitis, Acute
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Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder
NCT06229210
Recruiting
This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia or bipolar disorder.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/26/2024
Locations: Clinical Site, Orlando, Florida
Conditions: Schizophrenia, Bipolar Disorder
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: AdventHealth Transplant Institute, Orlando, Florida +1 locations
Conditions: NASH - Nonalcoholic Steatohepatitis
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EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis
NCT06178315
Recruiting
The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Chronic Pancreatitis
Register for Updates
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Orlando Research Center, Orlando, Florida
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates
The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Arnold Palmer Children's Hospital, Orlando, Florida
Conditions: Surgery, Anesthesia, Children
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Cardiac Performance System Data Collection Study
NCT05866666
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
ALL
Ages:
22 years and above
Trial Updated:
11/20/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Cardiac Disease
Register for Updates
Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study
NCT05220358
Recruiting
The RECOVER study is a self-controlled case series to evaluate whether the addition of Fostemsavir (Rukobia) to a stable HIV regimen in virologically suppressed patients living with HIV who never experience optimal CD4 T-cell count recovery can result in meaningful increases in different immunologic parameters such as CD4 T-cell count, CD4 T-cell percentage and CD4/CD8 ratio
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/02/2023
Locations: Orlando Immunology Center, Orlando, Florida
Conditions: HIV-1-infection
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A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations
NCT05163028
Recruiting
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS or EGFR mutations to determine the maximum tolerated dose and recommended Phase II dose of HBI-2376 and characterize its pharmacokinetic profile.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: Orlando Health, Inc., Orlando, Florida
Conditions: Non Small Cell Lung Cancer, Colorectal Cancer, Pancreatic Cancer, Solid Tumor, Cancer, Cancer of Pancreas, Cancer of Colon
Register for Updates
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
NCT04056247
Recruiting
This study will develop an algorithm of identifying patients with stage IV NSCLC and Melanoma who could benefit from cancer treatment they receive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: Florida Cancer Specialist and Research Institute, Orlando, Florida +1 locations
Conditions: Stage IV Non-small Cell Lung Cancer, Stage IV Small Cell Lung Cancer, Stage III Malignant Melanoma, Stage IV Malignant Melanoma
Register for Updates