There are currently 704 clinical trials in Orlando, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including AdventHealth Orlando, GSK Investigational Site, Orlando Clinical Research Center and Nemours Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
Recruiting
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
05/09/2024
Locations: Nemours Children's Clinic, Orlando, Florida
Conditions: Charcot Marie Tooth Disease
A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: AdventHealth Orlando, Orlando, Florida
Conditions: Multiple Myeloma
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Florida Hospital, Florida Center for Cellular Therapy, Orlando, Florida
Conditions: Infusion Reactions
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Florida Hospital Orlando, Orlando, Florida +4 locations
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
Recruiting
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/28/2024
Locations: Orlando Health, Inc., Orlando, Florida
Conditions: Lung Cancer
EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
Recruiting
This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/25/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Pancreatic Disease, Pancreatic Cancer, Pancreatic Cyst, Gastrointestinal Tumor, Bile Duct Diseases, Bile Duct Cancer, Lymph Node Disease, Submucosal Tumor of Gastrointestinal Tract, Gastrointestinal Cancer
Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment
Recruiting
PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: Adventist Health System/Sunbelt, Inc. d/b/a AdventHealth Orlando, Orlando, Florida
Conditions: Gastrointestinal Complication
Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.
Recruiting
The goal of this interventional study is to learn about the outcomes between two options for the management of malignant gastric outlet obstruction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: AdventHealth Orlando, Orlando, Florida
Conditions: Malignant Gastric Outlet Obstruction
ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies
Recruiting
ACE1831 is an off-the-shelf, allogeneic gamma delta T (gdT) cell therapy derived from healthy donors, that is under investigation for the treatment of CD20-expressing B-cell malignancies. The ACE1831-001 study is an open-label, Phase I, first-in-human (FIH) study that aims to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, and efficacy of ACE1831 in patients with CD20-expressing Non-Hodgkin lymphoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: AdventHealth Orlando, Orlando, Florida
Conditions: B-cell Lymphoma, Non Hodgkin Lymphoma, DLBCL, Primary Mediastinal Large B Cell Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CPM system reduces the rate of HF related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system against those who are not. This can either be done using institutions averages, if available, or through a control... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Heart Failure
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure ( BETA )
Recruiting
The primary purpose for this study is to support the hypothesis (pilot data) that the use of the CPM system reduces the rate of HF related events and the related healthcare cost. The study will also measure the impact on quality of care and patient satisfaction. In order to support the primary objective, the study will compare the outcomes and costs for patients using the CPM system against those who are not. This can either be done using institutions averages, if available, or through a control... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Heart Failure
Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections
Recruiting
Acute pancreatitis is one of the most common gastrointestinal disorders requiring hospitalization worldwide. Pancreatic fluid collections can occur as a consequence of acute and chronic pancreatitis and can result in significant morbidity and mortality, including significant abdominal pain, gastric outlet obstruction, biliary obstruction, organ failure, persistent unwellness, infection and sepsis. Symptomatic pancreatic fluid collections require treatment, and endoscopic drainage is considered... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Orlando Health, Orlando, Florida
Conditions: Acute Pancreatitis, Pancreatic Pseudocyst, Pancreatic Necrosis