Ohio is currently home to 3231 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis
NCT05521022
Recruiting
This is a multicenter, international, three-part, Phase 1 study designed to evaluate the safety, tolerability, and PK of rising single doses of AT-02 in healthy volunteers and in subjects with systemic amyloidosis and to assess the safety, tolerability, and PK of multiple doses of AT-02 in subjects with systemic amyloidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Amyloidosis; Systemic
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The Ohio State University Dermatology Biorepository
NCT03146676
Recruiting
This study will create and extend a source of clinical specimens for the future study of inflammatory skin disorders.
Gender:
ALL
Ages:
All
Trial Updated:
04/02/2024
Locations: OSU Dermatology West, Columbus, Ohio
Conditions: Hidradenitis Suppurativa
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Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
NCT05472441
Recruiting
This is a pragmatic randomized controlled trial (pRCT) that aims to test the effect of produce provision, diabetes education, and community referrals on hemoglobin A1c levels in individuals with type 2 diabetes experiencing food insecurity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Diabetes Mellitus, Type 2, Nutrition Poor, Food Deprivation
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Regional Monitoring of CF Lung Disease
NCT06339593
Recruiting
The main reason for this research study is to learn more about some new tests that are being developing for patients with Cystic Fibrosis (CF) to measure changes in the lungs. In this study, the focus will be to learn how stopping Airway Clearance (ACT) and re-starting ACT can affect these tests. These new tests include using a breathable gas called Xenon (Xe) with MRI (magnetic resonance imaging) to improve the pictures of changes in the lungs. The Xenon (Xe) gas that has been treated to have a... Read More
Gender:
ALL
Ages:
Between 12 years and 21 years
Trial Updated:
03/29/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Cystic Fibrosis
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Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support
NCT05668637
Recruiting
Invasive mechanical ventilation is one of the most important and life-saving therapies in the intensive care unit (ICU). In most severe cases, extracorporeal lung support is initiated when mechanical ventilation is insufficient. However, mechanical ventilation is recognised as potentially harmful, because inappropriate mechanical ventilation settings in ICU patients are associated with organ damage, contributing to disease burden. Studies revealed that mechanical ventilation is often not provide... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: Cleveland Clinic Foundation, Cleveland, USA, Cleveland, Ohio
Conditions: Invasive Mechanical Ventilation
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Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
NCT04968548
Recruiting
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/28/2024
Locations: Summa Health, Akron, Ohio
Conditions: Lung Cancer
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CERAMENT™| Bone Void Filler Device Registry
NCT04244942
Recruiting
A device registry to compile data on the performance of CERAMENT BONE VOID FILLER in normal use.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Orthopedic Disorder
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Exparel and Education to Avoid Opioids After Carpal Tunnel Release
NCT03867539
Recruiting
This trial seeks to use the long acting local anesthetic Exparel, in conjunction with opioid education, to attempt to avoid any post-operative opioid use following carpal tunnel surgery. This group will be compared with a "standard" group that receives non-liposomal bupivacaine, opioid education, and opioids.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Orthopedic Associates of Southwest Ohio, Dayton, Ohio
Conditions: Carpal Tunnel Syndrome
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Single Blinded First CMC Osteoarthritis Treatment
NCT03196310
Recruiting
Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Orthopedic Associates of Southwest Ohio, Centerville, Ohio
Conditions: Osteoarthritis Thumb
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Pilot Study Evaluating the Elasticity and Shear Wave Modulus (Stiffness) of the Median Nerve in Patients With Mild to Moderate Idiopathic Carpal Tunnel Syndrome Receiving OMT and Conservative Therapy
NCT06150443
Recruiting
To evaluate and quantify changes in the elasticity and shear wave modulus (stiffness) of the median nerve in patients diagnosed with mild to moderate carpal tunnel syndrome following osteopathic manipulative therapy.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/25/2024
Locations: Kettering Health, Dayton, Ohio
Conditions: Carpal Tunnel Syndrome
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Migraine Manager (R01)
NCT04567355
Recruiting
The objective of this trial is to test whether an online tailored intervention, Migraine Manager, is efficacious in improving headache outcomes compared to an attention control intervention in adolescents with migraines. We will conduct a randomized clinical trial to compare a sample of 80 youth (ages 11 to 17) with migraine receiving the online tailored adherence intervention to 80 youth in an attention control group. We will test whether adherence to healthy habit (hydration, regular meals, ex... Read More
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
03/25/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Migraine, Migraine Disorders
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Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens Wearers
NCT06182358
Recruiting
To compare the efficacy of XDEMVY ophthalmic drop to its vehicle control for the treatment of Demodex blepharitis and its impact on the soft contact lens wearing experience.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/22/2024
Locations: Site, Powell, Ohio
Conditions: Demodex Blepharitis
Register for Updates