Ohio is currently home to 3302 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Corneal Elastography and Patient Specific Modeling
Recruiting
The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have compu... Read More
Gender:
All
Ages:
Between 16 years and 80 years
Trial Updated:
01/23/2023
Locations: Cleveland Clinic Foundation Cole Eye Institute, Cleveland, Ohio
Conditions: Cornea; Ectasia, Refractive Errors, Keratoconus
Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)
Recruiting
Shoulder pain accounts for 16% of all musculoskeletal complaints in the healthy adult population. Subacromial impingement syndrome (SIS) is the most common cause of shoulder pain. Many patients with chronic pain from subacromial impingement syndrome (SIS) will fail treatment efforts and have longstanding pain. This project will evaluate the efficacy of a novel approach to treatment, percutaneous peripheral nerve stimulation, for participants with chronic shoulder pain due to subacromial impingem... Read More
Gender:
All
Ages:
Between 21 years and 100 years
Trial Updated:
01/20/2023
Locations: MetroHealth Medical Center, Cleveland, Ohio
Conditions: Shoulder Pain, Shoulder Impingement Syndrome, Shoulder Tendinitis, Shoulder Bursitis, Pain, Shoulder
Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC
Recruiting
The phase 3 study is to compare the efficacy and safety of palonosetron, a long-acting 5-HT3 receptor antagonist, by buccal film delivery compared to IV injection for the prevention of chemotherapy-induced nausea and vomiting. Subjects receive a single dose of palonosetron prior to moderately emetogenic chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/19/2023
Locations: Tri-County Hematology & Oncology Associates, Massillon, Ohio
Conditions: Chemotherapy-induced Nausea and Vomiting
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
Recruiting
The purpose of this research study is to determine if gentamicin is as effective treatment of acute uncomplicated cystitis (urinary tract infection) using aminoglycosides versus the current standards of care. The current standards of care in our region are often to prescribe a multi-day antibiotic prescription that is taken multiple times per day whereas gentamicin will be a one-time dose in the emergency department. Gentamicin is the medicine being studied.
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/18/2023
Locations: St. Elizabeth Youngstown Hospital, Youngstown, Ohio
Conditions: Urinary Tract Infections
Clinical Validation of the Ameda Pearl - An Electric, Hospital Grade, Multi-User Breast Pump
Recruiting
This study introduces a new Ameda electric multi-user, hospital-grade breast pump, the Ameda Pearl, to mothers who choose to exclusively breast pump until their infants are able to breastfeed.
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/18/2023
Locations: Summa Health, Akron, Ohio
Conditions: Breast Pumping
Move to Improve: Telehealth Exercise to Music for HD
Recruiting
The purpose of this study is to determine if a movement to music exercise program delivered via telehealth is feasible and safe for individuals with neurodegenerative disease and their caregivers (Aim 1). A secondary aim will be to determine if a movement to music exercise program delivered via telehealth improves balance, cognition, mobility, and quality of life (Aim 2).
Gender:
All
Ages:
21 years and above
Trial Updated:
01/18/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Huntington Disease
Droperidol on Prevention of Cannabis Hyperemesis Syndrome
Recruiting
The purpose of this study is to assess the efficacy of droperidol as a treatment of cannabinoid hyperemesis syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2023
Locations: Mercy Health - Austintown, Austintown, Ohio
Conditions: Cannabis Hyperemesis Syndrome
A Study on the Immune Response and Safety of a Combined Measles, Mumps, Rubella, Chickenpox Vaccine Compared to a Marketed Combined Vaccine, Given to Healthy Children 4 to 6 Years of Age
Recruiting
The main purpose of this study is to assess immune response and safety of various potencies of a measles, mumps, rubella, and varicella (MMRVNS) vaccines given to healthy children of 4 to 6 years of age.
Gender:
All
Ages:
Between 4 years and 6 years
Trial Updated:
01/16/2023
Locations: GSK Investigational Site, Dayton, Ohio
Conditions: Measles; Mumps; Rubella; Chickenpox
Integrating NIH Reset Stress Strategies Into DPT Curriculum
Recruiting
The goal of this longitudinal prospective cohort study is to determine effectiveness of integrating NIH reset stress strategies of deep breathing, muscle relaxation and mindfulness in DPT students in order to help them reduce stress throughout their schooling. The main question[s] it aims to answer are: Do performing the NIH reset stress strategies help DPT students manage their stress Do DPT students find these strategies helpful Participants will be asked to fill out initial intake forms and... Read More
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
01/13/2023
Locations: Youngstown State University, Youngstown, Ohio
Conditions: Stress
Impact of Preop Video on Patient Anxiety
Recruiting
To determine whether a pre-operative educational video has an impact on the anxiety of patients undergoing vaginal prolapse surgery
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/13/2023
Locations: Cincinnati Urogynecology Associates, Cincinnati, Ohio
Conditions: Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
Recruiting
The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD) using the Exablate Neuro system.
Gender:
All
Ages:
Between 30 years and 99 years
Trial Updated:
01/13/2023
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Tremor Associated With Tremor Dominant Parkinson's Disease
Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)
Recruiting
This open-label extension study will evaluate the long-term effects of GB002 (seralutinib) in subjects who previously participated in a GB002 PAH study.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/13/2023
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Pulmonary Arterial Hypertension