Rhode Island is currently home to 503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Providence, Warwick, East Providence and Johnston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
NCT03141021
Recruiting
First, the investigators plan to use a retrospective analysis to determine the clinical landscape of neurofibromatosis (NF)1-associated malignant peripheral nerve sheath tumor (MPNST) and precursor lesions (e.g., atypical or nodular plexiform neurofibromas). A worldwide database will be established, collecting, in a standardized manner, histologic, immunohistochemical, molecular, radiographic, treatment, and related clinical data from centers worldwide with expertise in these NF1-related cancers... Read More
Gender:
All
Ages:
All
Trial Updated:
11/20/2023
Locations: Lifespan, Providence, Rhode Island
Conditions: Malignant Peripheral Nerve Sheath Tumors
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SLC13A5 Deficiency Natural History Study - United States Only
NCT06144957
Recruiting
SLC13A5 deficiency (Citrate Transporter Disorder, EIEE 25) is a rare genetic disorder with neurodevelopmental delays and seizure onset in the first few days of life. This natural history study is designed to address the lack of understanding of disease progression. Additionally it will identify clinical and biomarker endpoints for use in future clinical trials.
Gender:
All
Ages:
All
Trial Updated:
11/17/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Citrate Transporter Deficiency, Epilepsy, Rare Diseases, Movement Disorders, Genetic Disorder, SLC13A5 Deficiency, EIEE25, Kohlschutter-Tonz Syndrome (Non-ROGDI), Citrate Transporter Disorder, DEE25
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Dose-escalation, Dose-expansion Study of Safety of PBCAR0191 in Patients With r/r NHL and r/r B-cell ALL
NCT03666000
Recruiting
This is a Phase 1/2a, nonrandomized, open-label, parallel assignment, dose-escalation, and dose-optimization study to evaluate the safety and clinical activity of PBCAR0191 in adults with r/r B ALL (Cohort A) and in adults with r/r B-cell NHL (Cohort N) and identify a treatment regimen most likely to result in clinical efficacy while maintaining a favorable safety profile.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Lifespan Cancer Institute at Rhode Island Hospital, Providence, Rhode Island
Conditions: Non-Hodgkin Lymphoma, B-cell Acute Lymphoblastic Leukemia
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Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis
NCT05990881
Recruiting
The purpose of this clinical trial is to gather information on the safety and effectiveness of botulinum toxin injection (or Botox) in the treatment of thumb joint pain/arthritis. People with thumb joint pain or arthritis usually receive steroid injections to help with the pain. However, this medicine does not always work well and also carries known important side effects. There is currently no alternative to this injection medicine. This clinical trial seeks to investigate botulinum toxin as a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: 235 Plain Street, Providence, Rhode Island
Conditions: Carpometacarpal Sprain, Thumb Sprain, Clostridium; Botulinum
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Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV
NCT05752500
Recruiting
The goal of this clinical trial is to examine 3 interventions designed to increase physical activity in older adults with HIV. We will examine 3 potential components of an intervention package: physical activity coaching, cognitive behavioral therapy targeted toward common barriers to physical activity such as low motivation or chronic pain, and a Fitbit-based social support intervention. Our primary outcome will be physical activity, defined as steps per day. Results will guide choice of interv... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
11/13/2023
Locations: Lifespan Affiliates, Providence, Rhode Island
Conditions: Hiv, Physical Inactivity, Aging
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Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study
NCT06085326
Recruiting
The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce Adverse Airway Outcomes (AAO) across 6 diverse pediatric intensive care units (ICUs).
Gender:
All
Ages:
19 years and below
Trial Updated:
11/07/2023
Locations: Hasbro Children's Hospital, Providence, Rhode Island
Conditions: Intubation Complication
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Generic Database of Very Low Birth Weight Infants
NCT00063063
Recruiting
The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.
Gender:
All
Ages:
14 days and below
Trial Updated:
11/07/2023
Locations: Brown University, Women & Infants Hospital of Rhode Island, Providence, Rhode Island
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
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Follow-up Visit of High Risk Infants
NCT00009633
Recruiting
The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may... Read More
Gender:
All
Ages:
Between 18 months and 26 months
Trial Updated:
11/07/2023
Locations: Brown University, Women & Infants Hospital of Rhode Island, Providence, Rhode Island
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
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Trial for Harm Reduction With Incentives & Vaping E-cigarettes
NCT06111053
Recruiting
The purpose of this study is to provide preliminary information on the effect of electronic nicotine delivery systems (ENDS) provisions and contingent incentives (CI) on smoking in individuals with overweight/obesity who smoke cigarettes (SWO). All participants will be provided information on the comparative risk of ENDS relative to cigarette smoking, and a randomized group of participants will be provided ENDS provisions for 6 weeks. All participants will complete breath samples for 28 days to... Read More
Gender:
All
Ages:
Between 21 years and 99 years
Trial Updated:
11/06/2023
Locations: Brown University School of Public Health, Providence, Rhode Island
Conditions: Obesity, Smoking Cessation
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Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease
NCT05361382
Recruiting
The purpose of this study is to compare/harmonize cross-sectional and longitudinal tau tangle measurements obtained with the tau PET radiopharmaceuticals Flortaucipir and MK-6240 to elucidate the advantages and caveats of their use in clinical trials/practice and provide parameters to integrate their estimates.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/03/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Alzheimer Disease
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Studying the Neuronal Basis of Human Social Cognition
NCT05324579
Recruiting
This proposal aims to study the role that the dorsal prefrontal cortex plays in human social cognition.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2023
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Neurosciences
Register for Updates
Youth Partners in Care for Suicide Prevention
NCT05304065
Recruiting
This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 15-24 who present to the Emergency Department (ED) with suicidal ideation or behavior. OUtcomes will be monitored at baseline and at 3, 6 & 12 month follow-up assessments.
Gender:
All
Ages:
Between 15 years and 24 years
Trial Updated:
11/03/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Suicide and Self-harm
Register for Updates