Tennessee is currently home to 1926 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Nashville, Memphis, Knoxville and Chattanooga. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study
NCT05464095
Recruiting
Patients with pulmonary arterial hypertension (PAH) have reduced health related quality of life (HRQOL) and impaired exercise capacity. Despite fourteen approved therapies, most patients die within ten years. Increasing physical activity is highly efficacious in PAH, resulting in six-minute walk distance (6MWD) and HRQOL improvement that often exceeds the effect of medications. Prior activity studies required inpatient rehabilitation, which is impractical, hard to sustain, and poorly scalable to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Pulmonary Arterial Hypertension
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Study of Stored Tumor Samples in Young Patients With Brain Tumors
NCT00897286
Recruiting
This laboratory study is looking at stored tumor samples in young patients with brain tumors. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
Gender:
ALL
Ages:
39 years and below
Trial Updated:
08/01/2024
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Brain and Central Nervous System Tumors
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Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
NCT06532708
Recruiting
The purpose of this study is to compare opioid prescribing practices by either routine provider prescribing practices, or with the use of a calculator, i.e., the Opioid Calculator, published by the University of Michigan (www.opioidcalculator.org), with the intent of decreasing the number of pills.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2024
Locations: University of Tennessee Health Science Center, Memphis, Tennessee
Conditions: Opioid Use, Postoperative Pain
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A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers
NCT06398730
Recruiting
This is a Phase 1, single-center, open-label, single-arm, dose-escalation positron emission tomography study to assess the safety and tolerability, immunogenicity, Pharmacokinetics, dosimetry, and biodistribution after GEH200521 (18F) Injection is co-administered with GEH200520 Injection in healthy volunteers. The estimated study duration for each subject is approximately 28 days. The primary study objective is to evaluate the safety and tolerability of the IMPs, the selected mass doses of GEH... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Healthy Volunteers
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Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
NCT06125743
Recruiting
The goal of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) to improve LEF self-management and reduce LEF-associated symptom burden, functional deficits, and improve quality of life in head and neck cancer (HNC) survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: Barbara Murphy, Nashville, Tennessee
Conditions: Lymphedema of the Head and Neck
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Enhanced Recovery After Surgery in Extremity Sarcoma
NCT04461171
Recruiting
The purpose of this study is to demonstrate the efficacy of implementing the enhanced recovery after surgery (ERAS) pathway in a prospective manner to patients undergoing surgical treatment for extremity sarcoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Sarcoma
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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
NCT06256588
Recruiting
The goal of this study is to assess the safety and effectiveness of Dostarlimab compared to Placebo in adult participants with HNSCC (Head and Neck Squamous Cell Carcinoma)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2024
Locations: GSK Investigational Site, Germantown, Tennessee
Conditions: Neoplasms, Head and Neck
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A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules
NCT06074133
Recruiting
This is a prospective, multicenter observational study aim at estimating the potential clinical utility of the CBM and at establishing the SOPs and protocols for a future randomized control trial.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
07/26/2024
Locations: Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Conditions: Pulmonary Nodule
Register for Updates
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
NCT05546580
Recruiting
Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat will be given in combination with gilteritinib, a drug that is already approved to treat patients with FLT3-mutated R/R AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2024
Locations: Sarah Cannon Research Institute, LLC, Nashville, Tennessee
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
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Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults
NCT05428228
Recruiting
The aim of the clinical trial is to evaluate the efficacy of two novel hydration products on rehydration following exercise.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
07/26/2024
Locations: The University of Memphis, Memphis, Tennessee
Conditions: Dehydration, Rehydration, Exercise Performance, Exercise Recovery, Cognitive Performance
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FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101)
NCT05950334
Recruiting
This is a phase 1 study of FT522 administered with rituximab in participants with relapsed/refractory B-cell lymphoma (R/R BCL). The primary objectives of the study are to evaluate the safety and tolerability of FT522 in combination with rituximab, and to determine the recommended phase 2 dose (RP2D) of FT522 in combination with rituximab; each objective will be assessed with or without conditioning chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Tennessee Oncology, Nashville, Tennessee
Conditions: Relapsed/Refractory B-Cell Lymphoma
Register for Updates
ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1
NCT05507203
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: Gastroenterology Center of the MidSouth PC, Germantown, Tennessee
Conditions: Ulcerative Colitis
Register for Updates