Tennessee Clinical Trials

A listing of Tennessee clinical trials actively recruiting patient volunteers.

Tennessee is a lively and lovely state known as the birthplace of bluegrass and the site of Graceland and Dollywood. It's also the place to go to see one of America's most iconic national parks, The Great Smoky Mountain National Park. Nashville is where you can immerse yourself in the history of the music business, while Memphis, Knoxville, and Gatlinburg each offer their own perks and sights. In any of these cities and beyond, sound healthcare is easy to find. Vanderbilt University Medical Center has been ranked #1 in the state, with more than 1,000 acute care beds in service.

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2204 trials found

Breast MRI in Women With Known or Suspected Breast Cancer and in Healthy Participants

NCT00474604

RATIONALE: Diagnostic procedures, such as MRI, may help diagnose breast cancer. It may also help doctors predict a patient's response to treatment. PURPOSE: This clinical trial is studying breast MRI in women with known or suspected breast cancer and in healthy participants.

Conditions: Breast Cancer
Phase: Not Applicable

Psoriasis Longitudinal Assessment and Registry

NCT00508547

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and guselkumab in patients with plaque and other forms of psoriasis. The study also includes patients receiving other therapies, such as non-biologic and other biologic agents. The registry also evaluates patient and disease characteristics, including patient-reported assessment of psoriatic arthritis (PsA); and clinical and quality of life outcomes.

Conditions: Psoriasis

ExploRâ„¢ Modular Radial Head Data Collection

NCT00521846

The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the ExploR Modular Radial Head.

Conditions: Elbow Fracture

Physiological Brain Atlas Development

NCT00575081

The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume. This initially was used to improve DBS implants for Parkinson's Disease, Dystonia, Essential Tremor, and OCD, but now includes data acquired during all stereotactic brain procedures.

Conditions: Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor, Epilepsy

Pathophysiology of Orthostatic Intolerance

NCT00608725

The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies. The syndrome is of undetermined etiology, but the syndrome causes impairment of a number of young adults, females more than males, with symptoms of tachycardia, fatigue, lightheadedness, palpitations, blurred vision, chest discomfort, difficulty concentrating, and dizziness with the upright posture. It is believed that many different pathophysiological processes can ...

Conditions: Tachycardia, Postural Orthostatic Tachycardia Syndrome
Phase: Not Applicable

Optical Spectroscopy in Evaluating Tumor Margins in Patients Who Have Undergone Surgery for Breast Tumors

NCT00625417

RATIONALE: Diagnostic procedures, such as optical spectroscopy, may help learn the extent of disease and allow doctors to plan better treatment. PURPOSE: This phase I trial is studying optical spectroscopy to see how well it works in evaluating tumor margins in patients who have undergone surgery for breast cancer.

Conditions: Breast Cancer
Phase: Not Applicable

Transthyretin Amyloidosis Outcome Survey (THAOS)

NCT00628745

THAOS is a global, multi-center, longitudinal observational survey open to all patients with transthyretin amyloidosis (ATTR), including ATTR-PN (polyneuropathy), ATTR-CM (cardiomyopathy) and wild-type ATTR-CM. It is open-ended with a minimum duration of 10 years. Patients will be followed as long as they are able to participate. The principal aims of this outcome survey are to better understand and characterize the natural history of the disease by studying a large and heterogenous patient popu ...

Conditions: Transthyretin Amyloidosis, Transthyretin Gene Mutations

HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

NCT00670735

The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric hydrocephalus. In addition to philanthropic funding, the HCRN has also received an NIH NINDS Challenge Grant to support the network infrastructure which allows for the conduct of this and other network studies. The HCRN consists of multiple Clinical Centers and the Data Coordinating Center (DCC). The HCRN ...

Conditions: Pediatric Hydrocephalus

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

NCT00673842

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack in the prior 5 years, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.

Conditions: Myocardial Infarction, Sudden Death

The Pediatric Anesthesia Quality Improvement Project

NCT00674388

The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.

Conditions: Surgery, Anesthesia, Children

Protocol For Collecting Data On Patients With Childhood Cancer

NCT00684580

Progress in the development of curative therapy for pediatric malignancies has resulted in increasing numbers of long-term childhood cancer survivors. This protocol is a means to provide continuing review of outcome and late toxicity for all patients actively being treated and previously treated for childhood cancer at St. Jude Children's Research Hospital.

Conditions: Childhood Cancer

Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

NCT00695279

This protocol (GENEFU) provides a mechanism for the 15-year followup period that the FDA requires for all participants in gene transfer protocols and assures that adequate followup can be maintained for a wide variety of participants on different individual gene therapy protocols at St. Jude Children's Research Hospital. GENEFU serves as an umbrella protocol for long-term follow-up (LTFU) for recipients of gene therapy/gene marked (GT/GM) products at St. Jude Children's Research Hospital. The F ...

Conditions: Severe Combined Immunodeficiency, Malignancy, Hematologic, Neuroblastoma, Neoplasm, Mucopolysaccharidosis I