Tennessee is currently home to 1922 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Nashville, Memphis, Knoxville and Chattanooga. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: The University of Tennessee Health Science Center, Memphis, Tennessee
Conditions: Burn Injury
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Physiologic Pacing for Symptomatic First-Degree Heart Block
NCT06245304
Recruiting
The purpose of this study is to determine if physiologic pacing will improve symptoms and outcomes in patients with symptomatic first-degree heart block (pr interval ≥250ms).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Ascension Saint Thomas Midtown, Nashville, Tennessee
Conditions: Symptomatic First-degree Heart Block
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Subscapularis Repair in Reverse Shoulder Arthroplasty
NCT05438914
Recruiting
This study will evaluate the subscapularis repair versus non-repair during a reverse shoulder arthroplasty (RSA).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/29/2024
Locations: The Campbell Clinic, Collierville, Tennessee
Conditions: Rotator Cuff Tear Arthropathy
Register for Updates
Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)
NCT04296864
Recruiting
This is a multi-center, double-masked, randomized, placebo-controlled, parallel-group, efficacy, safety, and tolerability study evaluating the efficacy of Dupilumab in the treatment of signs and symptoms of atopic keratoconjunctivitis (AKC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Blink Research Center, Memphis, Tennessee
Conditions: Atopic Keratoconjunctivitis
Register for Updates
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Gastro One - Germantown Office - Wolf Park Drive, Germantown, Tennessee
Conditions: NASH - Nonalcoholic Steatohepatitis
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Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias
NCT01013714
Recruiting
The purpose of this research study is to examine the effect of cardiac sympathetic denervation (CSD) surgery on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death. Subjects will be asked to participate in this research study if they have recurrent ventricular tachycardia (at least one ICD shock for ventricular tachycardia) and have undergone at least one catheter ablation procedure or have ventricular tachycard... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: Vanderbilt University, Nashville, Tennessee
Conditions: Sudden Cardiac Death, Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy
Register for Updates
Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)
NCT06178679
Recruiting
A Phase 3 Multi-Center, Randomized, Double Masked, Vehicle Controlled Study to Assess the Safety and Efficacy of ST-100 (vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed with Dry Eye Disease (DED)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Total Eye Care, PA, Memphis, Tennessee
Conditions: Dry Eye Disease
Register for Updates
Evaluation of Safety and Efficacy of Morpheus8 Applicator for the Treatment of Focal Hyperhidrosis of the Axillae Using Radio Frequency
NCT05860972
Recruiting
The InMode radio frequency Pro System with the Morpheus8 Applicator is a computerized system generating radio frequency energy, based on the underlying technology of Fractional RF. The Morpheus8 Applicator and 24 pin tip is used for the treatment of primary hyperhidrosis of the axillae
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Southeastern Dermatology, Knoxville, Tennessee
Conditions: Hyperhidrosis Primary Focal Axilla
Register for Updates
C-Brace Prospective Registry
NCT04640584
Recruiting
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
Gender:
ALL
Ages:
All
Trial Updated:
01/09/2024
Locations: Excel P&O, Kingsport, Tennessee
Conditions: Pareses, Lower Extremity
Register for Updates
Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke
NCT05941962
Recruiting
This study wants to know if using handheld dynamometry (HHD) to test leg strength in persons who have had a stroke, will reduce mistakes and give therapists better information to use for therapy. This study will collect normal values of leg muscle peak force production, cumulative peak force production, and sustained peak force production in patients with chronic stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Chronic Stroke, Weakness, Muscle
Register for Updates
The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma
NCT04047030
Recruiting
The study will prospectively enroll and follow 300 participants ages 18-60 surgically treated for a lower-extremity articular injury including fractures of the tibial plateau, pilon, ankle, and calcaneus.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/22/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Gait
Register for Updates
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT03941379
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: St. Thomas Health / Tennessee Retina, PC, Nashville, Tennessee
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
Register for Updates