There are currently 2868 clinical trials in Houston, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including M D Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Baylor College of Medicine and The University of Texas - MD Anderson Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Trauma-Informed Sleep Intervention for Children in Foster Care
NCT05646095
Recruiting
Sleep disturbances are pervasive and impairing among children who spend time in foster care but not a single prevention or intervention program for this fragile group targets sleep health. Poor sleep undermines effective self-regulation and stable biological rhythms, amplifying the negative impacts of early adversity/trauma on immediate and long-term functioning. Consistent with evidence that optimizing sleep is critical for trauma recovery, the investigators will adapt cognitive-behavioral trea... Read More
Gender:
ALL
Ages:
Between 6 years and 10 years
Trial Updated:
12/12/2023
Locations: Sleep and Anxiety Center of Houston, Houston, Texas
Conditions: Sleep Disturbance, Child Development, Mental Disorder, Child
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Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas
NCT05479123
Recruiting
The purpose of this study is to assess the baseline sleep pattern disruption for patients starting oral propranolol at the standard BID dosing regimen compared to the control (timolol) group and to determine if there is a significant improvement in the sleep patterns in infants taking oral propranolol on the TID dosing regimen versus the control (timolol) group
Gender:
ALL
Ages:
18 months and below
Trial Updated:
12/08/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Infantile Hemangioma
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Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
NCT04134780
Recruiting
This work explores the possibility of using ultrasound imaging and spectroscopy as a way of monitoring cell death, hence, tumour response to treatment. The hypothesis here is that it can be used as a way of monitoring early response to cancer treatment and predicting which patients continue on in their therapy to have a complete pathological response as a primary endpoint and tumour size decrease as a secondary endpoint. If this work is successful it could be used in the future early on in a can... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/07/2023
Locations: MD Anderson, Houston, Texas
Conditions: Breast Cancer
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Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
NCT06074315
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: West Houston Clinical Research Service, Houston, Texas
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
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Recovery and Outcomes From Stroke
NCT04007757
Recruiting
The investigators will perform follow-up on 500 cases of deep and lobar intracerebral hemorrhage to perform advanced neuroimaging before 45 days post stroke, and evaluations of motor and cognitive function at baseline, 3 months and 6 months to determine predictors of recovery, progressive cognitive or functional impairment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2023
Locations: Houston Methodist, Houston, Texas
Conditions: Intracerebral Hemorrhage
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International CDKL5 Clinical Research Network
NCT05558371
Recruiting
Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments and cortical visual impairment. While capability for disease modifying therapies is accelerating, there is a critical barrier for clinical trial readiness that may result in failure of these therapies, not due to lack of efficacy but due to lack of validated outcome mea... Read More
Gender:
ALL
Ages:
Between 1 month and 100 years
Trial Updated:
12/05/2023
Locations: Baylor College of Medicine/ Texas Children's Hospital, Houston, Texas
Conditions: CDKL5, CDKL5 Deficiency Disorder, CDD
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Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors
NCT04450732
Recruiting
Phase I Dose Finding Study for GQ1001 in Patients with HER2-Positive Advanced Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2023
Locations: M.D. Anderson Cancer Center, Houston, Texas
Conditions: HER2-positive Breast Cancer, HER2-positive Biliary Tract Cancer, HER2-Positive Salivary Gland Carcinomas, HER2-Positive Advanced Solid Tumor
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Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
NCT01937949
Recruiting
The purpose of this study is to evaluate clinical outcomes and quality of life measures in treated by endovascular aortic repair of juxtarenal, suprarenal, and type IV thoracoabdominal aortic aneurysms using custom-made Cook Zenith® Fenestrated AAA Endovascular Graft.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
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Complex Abdominal, TAAA, Aortic Arch Aneurysm or Dissections With Fenestrated/Branched Stent Graft
NCT02089607
Recruiting
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Complex Abdominal Aortic Aneurysm, Aortic Arch Dissection
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Solution Temperature and Fluid Deficit During Hysteroscopy
NCT05622097
Recruiting
Hysteroscopic surgery is widely used for the treatment of gynecological diseases, such as septum, synechiae, polyp and intrauterine fibroids. The complication rate is estimated as 0.22% and includes uterine perforation, massive bleeding, and fluid overload. Operative hysteroscopy intravascular absorption (OHIA) syndrome refers to fluid overload complications from operative hysteroscopies and is considered a major complication. Report describing the clinical association between irrigation fluid t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: University of Texas, Houston, Texas
Conditions: Surgery
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Laparoscopic Incision Closure s in Obese Patients
NCT05622110
Recruiting
Several methods for closure of trocar wounds are known in laparoscopic surgery including mostly transcutaneous or subcuticular suture or adhesive paper tape. Studies comparing laparoscopic incision closure in bariatric population are limited .This is a prospective study that will be conducted in a single tertiary medical center. s obese population comprise most of our surgical candidates, and due to the aforementioned, the aim of our study is to compare the outcomes of both techniques in obese w... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: University of Texas, Houston, Texas
Conditions: Obesity, Incision, Surgical
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Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension
NCT05881252
Recruiting
The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
12/01/2023
Locations: UT Houston, Houston, Texas
Conditions: Maternal Hypertension
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