There are currently 2879 clinical trials in Houston, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including M D Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Baylor College of Medicine and The University of Texas - MD Anderson Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
NCT05107765
Recruiting
The purpose of this study is to examine the effects of pioglitazone on stress-induced relapse risk in a laboratory model and to examine the effects of pioglitazone on drinking, stress/anxiety, and alcohol craving in the natural environment
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: The University of Texas Health Science Center of Houston, Houston, Texas
Conditions: Alcohol Use Disorder
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Marfan Syndrome Moderate Exercise Trial II
NCT05809323
Recruiting
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given limited evidence from in-vitro studies, and theoretical concerns, the majority of patients with MFS are restricted from certain physical activities. The lack of exercise and deconditioning have detrimental effects including increasing weakness, joint pain, decreased endurance, and... Read More
Gender:
ALL
Ages:
Between 10 years and 25 years
Trial Updated:
01/23/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Marfan Syndrome
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Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury
NCT06213012
Recruiting
It has been demonstrated that the human lumbosacral spinal cord can be neuromodulated with epidural (ESS) and transcutaneous (TSS) spinal cord stimulation to enable recovery of standing and volitional control of the lower limbs after complete motor paralysis due to spinal cord injury (SCI). The work proposed herein will examine and identify distinct electrophysiological mechanisms underlying transcutaneous spinal stimulation (TSS) and epidural spinal stimulation (ESS) to define how these approac... Read More
Gender:
ALL
Ages:
Between 22 years and 60 years
Trial Updated:
01/18/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Spinal Cord Injuries, Neuromodulation
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Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)
NCT05265169
Recruiting
To demonstrate that microwave ablation (MWA) of up to 3 hepatic metastases, each with a maximum diameter of ≤ 2.5 cm will result in a 2-year local progression free survival of at least 90%. This is a standard of care (SOC) study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Colorectal Liver Metastases
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Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)
NCT05752448
Recruiting
This study will enroll 120 women living with ovarian cancer following completion of initial treatment. Our objective is to test an intervention designed to provide support during the survivorship transition for this population, who live with a high degree of morbidity related to the illness and its treatment as well as a high risk of recurrence. Study participants will be randomly assigned to receive survivorship care using the POSTCare-O process or usual care. The primary outcome is quality of... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Dan L Duncan Comprehensive Cancer Center at the O'Quinn Medical Tower at Baylor St. Luke's Medical Center, Houston, Texas +1 locations
Conditions: Quality of Life, Depressive Symptoms, Ovarian Neoplasm
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Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
NCT04269239
Recruiting
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several ph... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/10/2024
Locations: Baylor College of Medicine Medical Center, Houston, Texas +1 locations
Conditions: Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
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The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma
NCT04047030
Recruiting
The study will prospectively enroll and follow 300 participants ages 18-60 surgically treated for a lower-extremity articular injury including fractures of the tibial plateau, pilon, ankle, and calcaneus.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/22/2023
Locations: University of Texas Health Science Center - Houston, Houston, Texas
Conditions: Gait
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CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
NCT05143996
Recruiting
CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/22/2023
Locations: MD Anderson, Houston, Texas
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
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A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
NCT04775485
Recruiting
FIREFLY-1 is an ongoing, Phase 2, multi center, open-label study to evaluate the safety and efficacy of oral pan-RAF inhibitor DAY101 in pediatric, adolescent, and young adult patients with recurrent or progressive low-grade glioma or an advanced solid tumor harboring a known RAF alteration.
Gender:
ALL
Ages:
Between 6 months and 25 years
Trial Updated:
12/21/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Low-grade Glioma, Advanced Solid Tumor
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A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT03941379
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Retina Consultants of Houston, Houston, Texas
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
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Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation
NCT06140810
Recruiting
Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements to guide post transplant treatment regiments. These procedures are done under general anesthesia which promotes lung tissue collapse (atelectasis). What is not known is the effect of atelectasis on intracardiac pressures which are a critical area of monitoring post-transplant patients for rejection.
Gender:
ALL
Ages:
All
Trial Updated:
12/20/2023
Locations: Texas Childrens Hospital, Houston, Texas
Conditions: Heart Transplant Failure, Anesthesia
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Substance Abuse Pre-Treatment Screening Study
NCT00439049
Recruiting
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/19/2023
Locations: University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute, Houston, Texas
Conditions: Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
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