Minnesota is currently home to 2107 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
ProACT Post-Approval Study
NCT03767595
Recruiting
The ProACT Post Approval Study is a 5-year prospective, open-label, multi-center study designed to evaluate the long-term incidence of urethral stricture and device erosion after ProACT implantation. In addition, the study will evaluate whether treatment with ProACT affects clinical outcomes after subsequent SUI therapies.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
11/25/2024
Locations: CentraCare- St. Cloud, Saint Cloud, Minnesota
Conditions: Stress Urinary Incontinence
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NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
NCT05992883
Recruiting
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).
Gender:
ALL
Ages:
40 years and above
Trial Updated:
11/22/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Thumb Osteoarthritis
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His Bundle Pacing in Bradycardia and Heart Failure
NCT03008291
Recruiting
Participants in this study will either have heart failure (HF) and are scheduled to undergo pace maker (PM) implantation, cardiac resynchronization therapy pacemaker (CRT-P), cardiac resynchronization therapy defibrillator (CRT-D) implantation, His bundle pacing (HIBP) or left bundle area pacing (LBAP) (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders), or have atrioventricular (AV) block or bradycardia and are scheduled to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Bradycardia, Heart Failure
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AI-SCREENDCM Decentralized Clinical Trial - Pilot Study
NCT06609174
Recruiting
The purpose of this study is to assess the feasibility and impact of screening FDR of DCM probands using a mobile ECG with the ability to transmit the ECG for cloud-based AI analysis to detect reduced left ventricular ejection fraction (LVEF). This protocol will examine the impact of incorporating the screening AI enhanced ECG into standard of care recommendations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cardiomyopathy
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Remote Trial - Tobacco Product Standard (VLNC)
NCT06442384
Recruiting
The goal of this pilot project is to explore the feasibility of a real-world marketplace study design examining the effects of a reduced nicotine product standard for cigarettes on smoking in the context of a flavor restriction vs. no restriction on e-cigarettes in smokers switched to very low nicotine content cigarettes.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Tobacco Use
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A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
NCT05824975
Recruiting
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-102 as a single agent and in combination with conventional anti-cancer drugs, pembrolizumab or trastuzumab deruxtecan(T-DXd) over a range of advanced and/or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mayo Clinic in Minnesota, Rochester, Minnesota
Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Soft Tissue Sarcoma (STS), Platinum-resistant Ovarian Cancer (PROC), Hepatocellular Carcinoma (HCC), Colorectal Cancer (CRC), HER2 Negative Breast Cancer, Cutaneous Melanoma, Renal Cell Carcinoma (RCC)
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Vyvanse in Children Aged 6 to 12 Years
NCT05416125
Recruiting
This study will randomize children who have difficulty maintaining a healthy weight to one of two treatment groups: lifestyle therapy plus lisdexamfetamine or lifestyle therapy plus placebo.
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
11/21/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Childhood
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A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
NCT06234605
Recruiting
This is a Phase 1b, open-label, multicenter, safety, tolerability and efficacy study of HC-7366 in combination with belzutifan (WELIREG™). This is a multipart study that consists of a HC-7366 monotherapy cohort, a combination dose escalation, and a combination dose expansion. Approximately 80 patients will be enrolled in this study (up to 20 patients will be enrolled into the HC-7366 monotherapy cohort, up to 30 patients into the combination dose escalation, and up to 30 patients into the combin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: HealthPartners Cancer Research Center, Saint Paul, Minnesota
Conditions: Renal Cell Carcinoma
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Study of Transcranial Direct Current Stimulation to Treat Epilepsy
NCT05673915
Recruiting
The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
11/20/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Focal Epilepsy, Generalized Onset Epilepsy, Sleep-related Epileptic Encephalopathy
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Non- Vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction
NCT05073276
Recruiting
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or combined PCL, anterior cruciate ligament (ACL), fibular collateral ligament (FCL), posterolateral corner (PLC), and MCL reconstructions (or any combination of multiple ligaments) can safely begin partial controlled weightbearing for the first six weeks after surgery.
Gender:
ALL
Ages:
Between 14 years and 59 years
Trial Updated:
11/20/2024
Locations: Twin Cities Orthopedics, Edina, Minnesota
Conditions: Knee Injuries
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Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction
NCT05073263
Recruiting
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing fibular collateral ligament (FCL) reconstruction alone or combined FCL and anterior cruciate ligament (ACL) reconstructions can safely begin full controlled weightbearing for the first six weeks after surgery.
Gender:
ALL
Ages:
Between 14 years and 59 years
Trial Updated:
11/20/2024
Locations: Twin Cities Orthopedics, Edina, Minnesota
Conditions: Knee Injuries
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Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke
NCT04968743
Recruiting
The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory rhythm (mu frequency) on motor excitability in stroke individuals.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Stroke
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