Connecticut is currently home to 1248 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Evaluation of Hip Preservation Outcomes
NCT05746533
Recruiting
The purpose of this study is to assess outcomes of hip preservation surgeries including open and arthroscopic treatment of femoroacetabular impingement (FAI).
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/24/2025
Locations: Yale New Haven Health, New Haven, Connecticut
Conditions: Hip Arthroscopy, Femoroacetabular Impingement
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Promoting Alcohol Treatment Engagement Post-hospitalization
NCT05338151
Recruiting
This study is a 3-arm randomized clinical trial to evaluate the effectiveness of hospital-initiated Alcohol Use Disorder treatment, involving a Brief Negotiated Interview (with referral and telephone booster) alone, BNI+facilitated provision of MAUD, BNI+facilitated provision of MAUD+CBT4CBT on AUD treatment engagement, alcohol use and healthcare utilization.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Alcohol Use Disorder
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Long-term Safety of Nipple Sparing Mastectomy in Women With GPV in Breast Cancer
NCT06888388
Recruiting
Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple sparing mastectomy (NSM) is associated with improved psychosocial and sexual well-being and is significantly better for body image and reducing feelings of disfigur... Read More
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
04/23/2025
Locations: Yale University, New Haven, Connecticut
Conditions: Breast Cancer Surgery
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Integrated Treatment for Enhancing Growth in Recovery During Adolescence
NCT06395467
Recruiting
This is a Phase II parallel group randomized controlled trial with 294 adolescents (age: 14-21 years) with alcohol and other drug \[AOD\] use disorder (hereafter substance use disorder), that compares two different active psychosocial interventions designed to address adolescent substance use disorder. Participants are recruited from our clinical settings and the community at two sites: one in the metro Boston, Massachusetts (MA) area and the other in the metro Farmington, Connecticut (CT), area... Read More
Gender:
ALL
Ages:
Between 14 years and 21 years
Trial Updated:
04/23/2025
Locations: UConn Health, Farmington, Connecticut
Conditions: Alcohol Use Disorder, Cannabis Use Disorder
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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
NCT06329401
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: UCONN Health, Farmington, Connecticut
Conditions: Progressive Pulmonary Fibrosis
Register for Updates
Becoming United in Lifestyle Decisions
NCT05796141
Recruiting
The goal of this project is to investigate how to enhance the effects of an online-only (mHealth) couples weight loss program. This study will use an innovative methodological framework, the Multiphase Optimization Strategy (MOST), to test four different strategies for weight loss and partner support in addition to a core intervention (i.e., dyadic action planning, joint feedback on goal progress, autonomy support training, and home environment modifications).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/23/2025
Locations: UConn's Weight Management Research Group, Hartford, Connecticut
Conditions: Overweight and Obesity
Register for Updates
A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa)
NCT06735755
Recruiting
This is a Phase 1/2, multicenter, open-label, single-ascending-dose study to evaluate the safety, tolerability, and efficacy of BEAM-301 in adult patients with GSDIa homozygous or compound heterozygous for the G6PC1 c.247C\>T (p.R83C) variant and to determine the optimal biological dose.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Clinical Study Site, Farmington, Connecticut
Conditions: Glycogen Storage Disease Type Ia
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Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)
NCT06214065
Recruiting
The goal of this observational study is to test the modulation effect of different transcranial magnetic stimulation (TMS) on the neural network supporting our ability to create mental representations of others (also known as mentalizing) in young adults with autism. The main question it aims to answers is can stimulation of the right temporoparietal junction can change brain activity related to mentalizing during social interaction in the stimulation area and other brain areas connected to it.... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
04/22/2025
Locations: Olin Neuropsychiatry Research Center (ONRC), Hartford, Connecticut
Conditions: Autism Spectrum Disorder
Register for Updates
Stepped Care for Patients to Optimize Whole Recovery
NCT05155163
Recruiting
This is a prospective, randomized clinical trial of 204 patients with opioid use disorder (OUD) and chronic pain (CP) to test the effectiveness of treatment as usual compared with Stepped Care for Patients to Optimize Whole Recovery (SC-POWR) to reduce pain interference (Aim 1) and decrease illicit opioid use, alcohol use, anxiety, depression, and stress, and improve sleep (Aim 2). Eligible participants will begin medications for opioid use disorder (MOUD) and will be randomized to receive SC-PO... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: APT Foundation, New Haven, Connecticut
Conditions: Opioid Use Disorder, Chronic Pain
Register for Updates
Black Church Treatment Study
NCT04580810
Recruiting
This study will conduct a randomized clinical trial comparing levels of treatment initiation, engagement, and alcohol outcomes for a novel treatment strategy (CBT4CBT delivered in the Black church) compared with traditional outpatient specialty addiction treatment for a large sample of Black adults with AUD. The purpose of this randomized clinical trial is to determine which setting (church or specialty clinic) (1) has better treatment initiation and retention rates and (2) better AUD outcomes... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Beulah Heights First Pentecostal Church, New Haven, Connecticut
Conditions: Alcohol Use Disorder
Register for Updates
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
NCT05803941
Recruiting
The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide tetraxetan also known as \[177Lu\]Lu-PSMA-617 or 177Lu-PSMA-617 and hereinafter referred to as AAA617. The study also seeks to further characterize (as possible) any other AAA617 causally related serious adverse event(s) in the long-term in adults with prostate cancer who received at least one dose of AAA617 from interventional, Phase I-IV Novartis... Read More
Gender:
MALE
Ages:
Between 18 years and 100 years
Trial Updated:
04/21/2025
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Prostate Cancer
Register for Updates
STOP AF First Post-Approval Study
NCT05227053
Recruiting
The STOP AF First PAS is a prospective, global, multi-center, observational trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/21/2025
Locations: Cardiology Associates of Fairfield County, Stamford, Connecticut
Conditions: Paroxysmal Atrial Fibrillation
Register for Updates