Connecticut is currently home to 1245 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Diabetes Learning in Virtual Environments Just in Time for Community Reentry
NCT05286892
Recruiting
The proposed study will use a randomized clinical trial design with non-equivalent control group and longitudinal design to evaluate the feasibility, acceptability, and preliminary effects of the Diabetes LIVE JustICE application. The design will incorporate repeated measures at 0, 6, and 12 weeks. Outcome variables will include recruitment assessments, participation, engagement, user experience, and measures proximally related to behavior change - e.g., diabetes knowledge, diabetes-related dist... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
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INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
NCT03037164
Recruiting
Stage A: To evaluate the safety and efficacy of red blood cells (RBCs) prepared with the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in patients who require RBC transfusion support. Stage B: To provide early access to the INTERCEPT pathogen reduction system for RBC in regions where a substantial proportion of the population has been infected or is at risk of a transfusion-transmissible infection. The objectives and design of... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
09/11/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Anemia
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Opioid Package Prototype (OPP)
NCT04598074
Recruiting
The overall objective of this clinical trial is to identify the impact of selected package features, known as the Opioid Package Prototype (OPP), on the safe and effective use of opioids. Our specific aims are: (Aim 1) to evaluate the effectiveness of OPP on prescribing, dispensing, and patient use of oxycodone among orthopaedic surgery patients receiving post-operative outpatient oxycodone for post-surgical pain management, and (Aim 2) to determine the feasibility of OPP for orthopaedic surgery... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/05/2023
Locations: UConn Health, Farmington, Connecticut
Conditions: Opioid Use, Opioid Prescribing, Dispensing, and Patient Use
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A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
NCT05181137
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Ulcerative Colitis
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Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
NCT05884190
Recruiting
The investigators primary project goal is to improve clinical outcomes, including mental health outcomes, among postpartum at-risk women experiencing health disparities by increasing awareness, detection, and timely care of postpartum hypertension, mental health and cardiovascular complications. The investigators will accomplish this by comparing the effectiveness of two multi-component multi-level healthcare delivery models focused on early detection and control of postpartum hypertension and t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Postpartum Hypertension
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Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)
NCT01196182
Recruiting
Congenital heart defects (CHD) are the most common major human birth malformation, affecting \~8 per 1,000 live births. CHD are associated with significant morbidity and mortality, and are second only to infectious diseases in contributing to the infant mortality rate. Current understanding of the etiology of pediatric cardiovascular disorders is limited. The Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) is a multi-center, prospective observational cohort study. Participants will b... Read More
Gender:
ALL
Ages:
99 years and below
Trial Updated:
08/29/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Congenital Heart Defects
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OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
NCT05405374
Recruiting
The objective of this clinical study is to compare OSTEOAMP SELECT Fibers to Infuse Bone Graft, in terms of effectiveness and safety, when used as a bone graft substitute in in skeletally mature patients qualified for 2-lumbar interbody fusion (LIF) by means of an intra-patient control model.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
08/25/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
Register for Updates
Kids Rehydration During Exercise
NCT05989607
Recruiting
The present study aims to measure the impact of consuming a lower sugar flavored water compared to an equal amount of plain water during exercise on selected rehydration markers in healthy children. Participants will complete two experimental visits designed to examine the differentiating effects of one of two selected beverages (1) lower sugar flavored water beverage and 2) plain water) on certain hydration markers and related perceptual variables during repeated bouts of exercise in a warm env... Read More
Gender:
ALL
Ages:
Between 8 years and 10 years
Trial Updated:
08/04/2023
Locations: University of Hartford, West Hartford, Connecticut
Conditions: Dehydration in Children, Dehydration Following Exertion (Disorder)
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Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol
NCT05968729
Recruiting
The purpose of this work is to conduct a comparative research-focused study to evaluate the effectiveness of how purposefully induced asymmetric walking protocols restore healthy, symmetric limb loading in individuals following post-anterior cruciate ligament reconstruction (ACLR) surgery. Additionally, computational modeling and machine learning to model knee loading in the clinic to determine the optimal asymmetric walking protocol to restore healthy gait in post-ACLR individuals.
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
07/27/2023
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Anterior Cruciate Ligament Reconstruction
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Total Shoulder Arthroplasty Multi-Center Registry
NCT03511586
Recruiting
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/27/2023
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Shoulder Arthroplasty
Register for Updates
The Impact of a Telephone Reminiscence Program
NCT05977608
Recruiting
The purpose of this study is to better understand how a telephone reminiscence program impacts reminiscence functions and mental health outcomes in community-dwelling older adults.This study will take 12 weeks to complete and will include approximately 90 study participants. Participants will be randomly assigned to one of two telephone reminiscence groups.They will be either assigned to begin a telephone reminiscence program immediately or in 6 weeks. Participants will receive automatic calls t... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
07/26/2023
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Mental Health, Loneliness, Social Isolation
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Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0
NCT05965934
Recruiting
This study is a multi-center, prospective, randomized (2:1), open-label study to evaluate the safety and efficacy of DSR therapy using the Infusate 2.0 peritoneal solution (composed of 30% icodextrin and 10% dextrose) in diuretic resistant patients with HF and persistent volume overload.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure, Volume Overload
Register for Updates