Connecticut is currently home to 1218 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Impact of Work Activity on SUD Outcomes
NCT04969081
Recruiting
To date, there are no studies of the therapeutic effects of varied work-focused programs in Veterans undergoing outpatient substance use disorder (SUD) treatment. The investigators propose a randomized clinical trial to test the effects of work-focused programs on improving sobriety and other clinical outcomes in Veterans early in the course of recovery from SUD. Veterans will be randomized to either receive or not receive referral for work-focused therapeutic programs. Primary aim is to examine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Substance-related Disorders
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Pharmacological and Behavioral Treatment After Bariatric Surgery
NCT05157698
Recruiting
This study will compare the effectiveness of behavioral and pharmacologic treatment, alone and combined, for improvements in weight loss, cardiovascular risk factors, and psychosocial functioning following metabolic and bariatric surgery.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Obesity
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Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the OASIS Trial
NCT04809064
Recruiting
This clinical trial will investigate the effects of three surgical procedures and the associated post-operative rehabilitation to optimize time to return to military duty, work and sports, and patient-reported physical function for military personnel and civilians with traumatic anterior shoulder instability and 10-20% glenoid bone loss.
Gender:
ALL
Ages:
Between 17 years and 50 years
Trial Updated:
10/08/2024
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
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Aspiration in Acute Respiratory Failure Survivors 2
NCT05108896
Recruiting
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Dysphagia, Aspiration
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A Study of Sacituzumab Govitecan (IMMU-132) in Platinum-resistant Ovarian Cancer Patients
NCT06028932
Recruiting
This is a non-randomized Phase 2 study of sacituzumab govitecan (IMMU-132) in subjects with recurrent or persistent platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancers.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut
Conditions: Ovarian Carcinoma
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The Impact of Preoperative Olanzapine on Quality of Recovery After Discharge from Ambulatory Surgery
NCT05676294
Recruiting
The primary objective of this phase 2 randomized controlled trial is to determine whether the pre-operative administration of olanzapine (5 mg PO) improves quality of recovery (assessed by the Quality of Recovery-40 (QoR-40) survey) on postoperative day 1 in patients having ambulatory surgery with general anesthesia. The secondary objectives of this study are to determine whether there are differences in quality of recovery on postoperative day 2, presence of post-discharge nausea, presence of... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
10/04/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Postoperative Nausea and Vomiting
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
NCT06209359
Recruiting
Randomized double-blind placebo-controlled crossover study design
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure, Diuretic Resistance
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Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
NCT06172660
Recruiting
The purpose of this study is to continue evaluating how well the RSV vaccines work as they are currently being used in routine clinical practice. Some of the questions that the investigators hope to answer with this study are: 1) What is the overall effectiveness of these vaccines? 2) How long does immunity last? 3) How effective are the vaccines against new strains? 3) Does the vaccine's effectiveness vary by age?
Gender:
ALL
Ages:
12 months and below
Trial Updated:
10/03/2024
Locations: Yale Child Health Research Center, New Haven, Connecticut
Conditions: RSV Infection
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Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
NCT04131829
Recruiting
The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/03/2024
Locations: Yale OCD Research Clinic - CMHC/CNRU, 34 Park ST, New Haven, Connecticut
Conditions: Obsessive-Compulsive Disorder
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ABC-CT Pre-School Feasibility Study
NCT06413316
Recruiting
This is a multicenter study that aims to determine whether the EEG and ET experiments studied in the ABC-CT Phase 1 and ABC-CT Confirmation studies can be successfully used with 3-5-year-old children and to determine the viability of these measures as potential biomarkers in 3-5-year-old children with ASD. Blood (DNA) samples will be collected from participants with ASD and biological parents for future genomic analyses, and raw, processed, and analyzed data will be shared to create a community... Read More
Gender:
ALL
Ages:
Between 3 years and 5 years
Trial Updated:
10/01/2024
Locations: Yale Child Study Center, New Haven, Connecticut
Conditions: Autism Spectrum Disorder
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240
Recruiting
Study LTI-401 is an open-label, multicenter study which will evaluate the safety and tolerability of LIQ861 in subjects who have WHO Group 1 \& 3 PH.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/01/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Pulmonary Hypertension, Interstitial Lung Disease
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Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
NCT05784805
Recruiting
In this study, the investigators propose Pulsed Low-Intensity Focused Ultrasound (PLIFU) stimulation of brain regions that modulate (thalamus) or generate focal motor seizures (primary motor cortex), with the goal of ameliorating seizure activity in subjects in non-convulsive or focal motor status epilepticus. The course of treatment will consist of an initial 10 minute PLIFU treatment session with an option for a 2nd session if necessary. The primary objective of this study is to determine whe... Read More
Gender:
ALL
Ages:
Between 19 years and 85 years
Trial Updated:
10/01/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Seizures
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