Indiana is currently home to 1219 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Indianapolis, South Bend, Fort Wayne and Evansville. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
NCT05124808
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
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I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms in Hispanic Individuals
NCT06099197
Recruiting
This study is a randomized, controlled trial (RCT) to evaluate usability and acceptability, and met and unmet needs from a caregiver intervention app, Brain CareNotes, among unpaid Hispanic caregivers of patients with dementia. Brain CareNotes provides support for management of the behavioral and psychological symptoms of dementia (BPSD) displayed by care recipients. Over 10 months, the trial will enroll 40 Hispanic caregivers of community-dwelling patients diagnosed with Alzheimer's disease or... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: Indiana University, Bloomington, Indiana
Conditions: Caregiver Burden, Alzheimer Disease
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Temporal Interference Neurostimulation and Addiction
NCT04432064
Recruiting
This project aims to develop a line of research using new non-invasive neurostimulation technology to treat adults with opioid use disorders (OUDs). In the short term, the investigators aim to identify novel target brain regions for neurostimulation treatment and characterize their effects behaviorally and neurally. In the longer term, investigators aim to use these preliminary data to justify NIH sponsored clinical trials to apply transcranial direct current stimulation and non-invasive deep br... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
06/07/2024
Locations: Indiana University, Bloomington, Indiana
Conditions: Nicotine Use Disorder, Substance Use Disorders
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Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application
NCT05506085
Recruiting
Deep Brain Stimulation (DBS) is a neurosurgical procedure used to treat tremors, and dystonia. This study will enroll people who have a form of focal dystonia that affects their vocal cords called Adductor Laryngeal dystonia (ADLD). Participants will undergo Deep Brain Stimulation surgery to treat laryngeal dystonia as part of their clinical care. Before surgery, as part of the study they will have specialized testing to study the movement of the vocal cords, as well as functional magnetic reson... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/06/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
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Functional Assessment in Liver Transplantation
NCT03228290
Recruiting
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive function. Subjects will again undergo assessments at every clinic visit through 12 months after transplant. Then, they will be followed annuall... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: End Stage Liver Disease
Register for Updates
High-Intensity, Dynamic-stability Gait Training in People With Multiple Sclerosis
NCT05735691
Recruiting
The goal of this clinical trial is to improve walking speed, balance, and walking in the community for people with multiple sclerosis. This trial involves intense exercise combined with walking on a shaky treadmill. Walking on a shaky treadmill helps to practice balance and intense exercise promotes the ability to walk faster and farther. In this study, participants will train with a combination of high or low intensity, and with a stable or shaky treadmill. Walking speed and endurance, balance... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/03/2024
Locations: Rehabilitation Hospital of Indiana, Indianapolis, Indiana
Conditions: Multiple Sclerosis
Register for Updates
Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Riley Hospital for Children at IU Health, Indianapolis, Indiana
Conditions: Bronchiolitis Acute Viral
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A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas
NCT05641844
Recruiting
The goal of this clinical trial is to assesses the safety of autologous RD2 Ver.02 as compared to a control for managing transsphincteric and intersphinsteric anal fistulas. The main questions it aims to answer are: Assess the safety and efficacy of RD2 Ver.02 in anal fistula application, compared to control. Complication rate by 6 months of anal fistula treatment with RD2 Ver.02 compared to control. Recurrence of anal fistula at 12 months post-treatment Incidence of perirectal infection by... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2024
Locations: Franciscan Health, Indianapolis, Indiana
Conditions: Anal Fistula
Register for Updates
Postprandial Effects of Animal Versus Plant-Based Protein
NCT06445296
Recruiting
Shifting away from diets high in animal products towards more plant predominant diets is recommended by many health organizations to both reduce the negative environmental impacts of animal agriculture and to improve health outcomes. As a result, a number of plant-based meat alternatives such as Beyond Meat have been formulated to promote increased plant consumption. However, evidence is limited on the impact of newer plant-based meat alternatives on common cardiometabolic risk factors. The inve... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
05/31/2024
Locations: Health Professions Building, Ball State University, Muncie, Indiana
Conditions: Overweight or Obesity
Register for Updates
The Movie Theater Study
NCT06444984
Recruiting
Increasing attention has been paid to meals with unusual characteristics that are consumed on a semi-regular basis (e.g., "tailgating," pizza buffets). The purpose of this study is to describe the acute cardiometabolic effects of a cinema-style meal rich in refined sugar, total carbohydrate, and moderate in fat (i.e., soda, popcorn, candy).
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/31/2024
Locations: Health Professions Building, Ball State University, Muncie, Indiana
Conditions: Hyperglycemia, Postprandial, Hyperinsulinemia
Register for Updates
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
NCT05462106
Recruiting
The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndrome.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
05/30/2024
Locations: Indiana University / IU Health, Indianapolis, Indiana
Conditions: Alzheimer's Disease, Prodromal Alzheimer's Disease, Amyloid Plaque, Beta-Amyloid, Alzheimer's Disease in Down Syndrome
Register for Updates
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
NCT04400071
Recruiting
Music therapy has become a standard palliative care service in many pediatric and adult hospitals; however, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. This study builds on prior work examining the psychosocial mechanisms of action underlying an Active Music Engagement (AME) intervention, designed to help manage emotional distress and improve positive health outcomes in young childre... Read More
Gender:
ALL
Ages:
Between 3 years and 8 years
Trial Updated:
05/29/2024
Locations: Riley Hospital for Children, Indianapolis, Indiana
Conditions: Acute Lymphoblastic Leukemia, Pediatric, Pediatric Cancer
Register for Updates