Indiana is currently home to 1189 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Indianapolis, South Bend, Fort Wayne and Evansville. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Impact of Beef on Muscle Fatigue in Older Adults
NCT05860088
Recruiting
The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults. The aims are: AIM 1: To test the hypothesis that muscle fatigue is attenuated in older adults consuming beef compared to older adults consuming a plant-based diet. AIM2: To test the hypothesis that daily beef consumption improves biochemical indicators related to muscle fatigue. Participants will be randomized to consume either a beef-based diet or... Read More
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
02/07/2024
Locations: Indiana University Bloomington, Bloomington, Indiana
Conditions: Muscle Weakness, Muscle; Fatigue, Heart, Older Adults
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Pediatric Cardiomyopathy Mutation Analysis
NCT02432092
Recruiting
The goal of this protocol is to obtain information from individuals with cardiomyopathy and from their families in order to elucidate the molecular genetics of this disorder. This will provide the basis for future genetic counseling as well as contribute to elucidating the biology of normal and abnormal cardiac function.
Gender:
ALL
Ages:
All
Trial Updated:
02/05/2024
Locations: IU School of Medicine, Indianapolis, Indiana
Conditions: Cardiomyopathies, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Restrictive Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy, Left Ventricular Non-compaction Cardiomyopathy
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Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
NCT02432079
Recruiting
The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder. The knowledge gained from the analysis of this information will provide the basis for future genetic counseling as well as contribute to knowledge about the biology of normal and abnormal development of left-right anatomic asymmetry.
Gender:
ALL
Ages:
All
Trial Updated:
02/05/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Heterotaxy Syndrome, Congenital Heart Defects
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Prevalence of Hemorrhagic Myocardial Infarction in the United States
NCT06162039
Recruiting
Registry analysis for prevalence of hemorrhagic myocardial infarction in the United States
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2024
Locations: Krannert Cardiovascular Research Center, Indianapolis, Indiana
Conditions: Acute Myocardial Infarction
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STAT: Standard Therapy Plus Active Therapy
NCT04368117
Recruiting
The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury. This randomized multi-center trial is designed with two parallel treatment groups: STAT and ST. Efficacy of the STAT protocol will be determined through comparison to the ST only group. It will be conducted at seven burn centers.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: Health and Hospital Corporation dba Eskenazi Health, Indianapolis, Indiana
Conditions: Burn Injury, Physical Injury, Thermal Burn
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Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder
NCT06229210
Recruiting
This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia or bipolar disorder.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/26/2024
Locations: Clinical Site, Indianapolis, Indiana
Conditions: Schizophrenia, Bipolar Disorder
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The Indiana Myeloma Registry
NCT03616483
Recruiting
This is a prospective, non-interventional, observational study. The purpose of this study is to collect data and bio-specimens that will support future research
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: Indiana University Simon Cancer Center, Indianapolis, Indiana
Conditions: Plasma Cell Dyscrasias
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: ASHA Clinical Research - Munster, Hammond, Indiana
Conditions: NASH - Nonalcoholic Steatohepatitis
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ACL Bone Health and Loading Study
NCT04682392
Recruiting
The purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health. Hypothesis: The BFR group will have decreased bone mineral loss and improved functional performance compared to control group.
Gender:
ALL
Ages:
Between 16 years and 22 years
Trial Updated:
01/19/2024
Locations: Parkview Athletic Rehab, Fort Wayne, Indiana
Conditions: ACL Tear
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Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With Dupilumab
NCT05694884
Recruiting
Multicenter, randomized, double-blind, placebo-controlled, parallel arm clinical study designed to evaluate the efficacy and safety of eblasakimab in participants with moderate-to-severe atopic dermatitis (AD) previously treated with dupilumab.The study consists of a 16-week treatment period and an 8-week follow-up period up to Week 24. Eligible participants will be randomized into one of the 2 treatment arms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: ASLAN Investigative Site, New Albany, Indiana
Conditions: Atopic Dermatitis
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C-Brace Prospective Registry
NCT04640584
Recruiting
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
Gender:
ALL
Ages:
All
Trial Updated:
01/09/2024
Locations: Kenney Orthopedics - Evansville, Evansville, Indiana
Conditions: Pareses, Lower Extremity
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Coflex PS3 Actual Conditions for Use Study
NCT02555280
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: 24_Unity Surgical Center, LLC, Lafayette, Indiana
Conditions: Spinal Stenosis Lumbar
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