Ohio is currently home to 3226 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Overlapping Pain Trajectory Study
NCT05752396
Recruiting
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/20/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
Register for Updates
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
NCT05476276
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Clinical Inquest Center, Beavercreek, Ohio
Conditions: Painful Diabetic Neuropathy
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Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
NCT06460272
Recruiting
This study is a human-centered, three-arm, parallel-group, randomized control, implementation trial (n=75) to compare MTM (Medically Tailored Meals) only (14 meals delivered weekly for 10 weeks) vs. MTM + SMA (Shared Medical Appointments; once weekly sessions for 10 weeks) vs. a wait-list control group (MTM-Later) in patients with hypertension, type 2 diabetes, obesity, and/or metabolic syndrome. All intervention components will be culturally congruent (e.g., MTMs will include food that converge... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Hypertension, Type2diabetes, Metabolic Syndrome, Obesity
Register for Updates
Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)
NCT06133101
Recruiting
A randomized, controlled study of standard soy milk consumption compared to 2% fat cow's milk consumption in children with Non-alcoholic Fatty Liver Disease (NAFLD). The investigators hypothesize that the daily consumption of soy isoflavones found in the soy milk will be beneficial in reducing NAFLD and other obesity-related comorbidities. The investigators do not expect any adverse endocrine or metabolomic effects from the consumption of soy isoflavones.
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
08/19/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates
Identifying the Neural Signature of Exercise to Advance Treatment of PD Cognitive Declines
NCT05972759
Recruiting
Twenty-five participants with PD utilizing the Medtronic Percept PC DBS system will be enrolled for this project and complete a single bout of both FE and VE. The 150-minute experimental session will be completed in the OFF antiparkinsonian and Off-DBS state.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Parkinson Disease
Register for Updates
Physiological Effects Ketone Ester in Heart
NCT05924802
Recruiting
The study is aimed to phenotype with cardiac MRI the physiological effects of ketone esters on the heart. Patients with heart failure will be recruited and given ketone esters or placebo in a randomized fashion. Cardiac MRI will be performed at baseline and after 12weeks follow up.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Cardiovascular Innovation Research Center, Cleveland, Ohio
Conditions: Heart Failure
Register for Updates
The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease
NCT05905302
Recruiting
Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication. Bilateral neural activity of the STN will be continuously recorded for 130 minutes (pre-, during FE or VE and post-exercise). The Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III Motor Exam and upper extremity force-tracking task will be used to determine motor response to exercise.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Parkinson Disease, Deep Brain Stimulation
Register for Updates
Sleep Timing, Eating and Activity Measurement Study
NCT04992611
Recruiting
There is strong reason to believe that sleep promotion during adolescence could yield long-term health rewards; the investigators' data show that, when they get more sleep, Morning Larks have impressively reduced intake of overall calories and foods high in glycemic load that are linked to long-term health risk. Before that can be translated into major public health interventions, however, the field needs to understand why similar changes in sleep had no effect, or even an adverse effect, on ado... Read More
Gender:
ALL
Ages:
Between 14 years and 18 years
Trial Updated:
08/19/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Sleep, Circadian Rhythm Disorders, Dietary Habits
Register for Updates
Childhood Cancer Survivor Study
NCT01120353
Recruiting
The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximately 50,000 survivors of cancer, diagnosed before 21 years of age, between 1970 and 1999 and 10,000 sibling controls. This project will study children and young adults exposed to specific therapeutic mod... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/19/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Cancer
Register for Updates
Visual Performance of Center Distance Daily Disposable Multifocal Lenses
NCT06475053
Recruiting
The purpose of this study is to compare visual performance (high and low contrast acuity, reading acuity, contrast sensitivity, stereoacuity, accommodative response, eye hand coordination, far near vision, and dynamic vision) between Visioneering Technologies, Inc. NaturalVue Multifocal and CooperVivion MiSight.
Gender:
ALL
Ages:
Between 9 years and 30 years
Trial Updated:
08/16/2024
Locations: The Ohio State University College of Optometry, Columbus, Ohio
Conditions: Myopia
Register for Updates
Comparing Two Models of Well-Child Care for Black Families
NCT05852392
Recruiting
Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT) is a team-based approach to care that utilizes a community health worker in a health educator role ("Parent's Coach") to provide many of the Well-Child Care (WCC) services that children and families should receive, addresses specific needs faced by families in low-income communities, and decreases reliance on the clinician as the primary provider of WCC services. The model was developed in partnership with clinics and parents... Read More
Gender:
ALL
Ages:
Between 9 months and 15 months
Trial Updated:
08/16/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Pediatric, Well Child Care
Register for Updates
A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
NCT04496349
Recruiting
The goal of this study is to evaluate the pharmacokinetics (PK), safety, and efficacy of APG-115 as a single agent or in combination with APG-2575 in patients with T-PLL and NHL.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2024
Locations: Ohio State University, Columbus, Ohio
Conditions: T-Prolymphocytic Leukemia, Non-Hodgkins Lymphoma
Register for Updates