Ohio is currently home to 3314 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
NCT05783297
Recruiting
This research study uses a cluster randomized controlled trial design to evaluate the effectiveness of Treatment Text (TXTXT) intervention on adherence and viral load suppression at 3- and 6- months post intervention initiation for youth and young adults with HIV. A total of 12 clinics will be randomized into one of the following two conditions: Comparison Arm (n=6 clinics)- Clinics randomized to the comparison arm will have participants receive the standard of care for 3 months, followed by a... Read More
Gender:
All
Ages:
Between 16 years and 35 years
Trial Updated:
06/29/2023
Locations: University of Cincinnati, Cincinnati, Ohio
Conditions: HIV Infections
Register for Updates
Evaluate the Safety and Efficacy of Dura Sealant Patch in Reducing CSF Leakage Following Elective Cranial Surgery
NCT04086550
Recruiting
The objective of the study is to clinically assess the safety and effectiveness of LIQOSEAL® as a means of reducing intra- as well as post-operative CSF leakage in patients undergoing elective cranial intradural surgery with a dural closure procedure to show noninferiority compared to a control group.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/29/2023
Locations: University of Cincinnatti, Cincinnati, Ohio
Conditions: Cerebrospinal Fluid Leak
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A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
NCT03588975
Recruiting
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/29/2023
Locations: Akron Children's Hospital, Akron, Ohio
Conditions: Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Osteochondritis Dissecans (OCD)
Register for Updates
IMPACT - AndHealth Autoimmune Research Registry
NCT05883371
Recruiting
This is a patient research registry aimed at evaluating the effectiveness of a comprehensive, root-cause medical approach ("AndHealth program") for autoimmune disorders. This approach involves a combination of pharmacological and non-pharmacological therapies offered under the care of a licensed physician with the support of health coaches. While protocol guidance is provided, the therapeutic approach is personalized to the individual needs of patients. The autoimmune disorders of focus in this... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/28/2023
Locations: AndHealth, Columbus, Ohio
Conditions: Arthritis, Rheumatoid, Arthritis, Psoriatic, Psoriasis, Ankylosing Spondylitis, Autoimmune Diseases
Register for Updates
Zinc Effect on Inflammation and Cardiovascular Risk in HIV
NCT05085834
Recruiting
To study the effect of short-term zinc supplementation on improving inflammation, metabolic, and cardiovascular risk among HIV infected patients on stable anti-retroviral therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
06/28/2023
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Inflammation, Cardiovascular Diseases, Zinc Deficiency
Register for Updates
The PulsePoint Study
NCT04806958
Recruiting
This randomized controlled trial will evaluate whether use of the PulsePoint system increases bystander CPR or defibrillator use compared to standard dispatch procedures in patients who suffer non-traumatic, out-of-hospital cardiac arrest in a public location. Half of all suspected cardiac arrest 9-1-1 calls in a public location will receive PulsePoint alerts (treatment arm). The other half of this eligible patient cohort will receive standard dispatch procedures (control arm).
Gender:
All
Ages:
All
Trial Updated:
06/28/2023
Locations: Columbus Division of Fire, Columbus, Ohio
Conditions: Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
Register for Updates
Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT
NCT04702373
Recruiting
This is a Phase III randomized controlled trial of a passive ROM exercise program that will be performed in infants with HLHS and other single right ventricle anomalies following the Norwood procedure at PHN and Auxiliary Centers.
Gender:
All
Ages:
29 days and below
Trial Updated:
06/28/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Congenital Heart Disease
Register for Updates
Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery
NCT04233385
Recruiting
About 25-50% of women who undergo breast cancer surgery develop persistent chest wall pain and shoulder mobility limitations following surgery. The pain and mobility limitations adversely affect quality of life, sleep, and body image. Unfortunately, current treatments for pain and mobility limitations have variable efficacy. Based on a review of relevant pre-, intra-, and post-operative factors, investigators reasoned that myofascial massage may address contributors to pain and mobility limitati... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/28/2023
Locations: MetroHealth Medical Center, Cleveland, Ohio
Conditions: Breast Cancer, Mastectomy; Lymphedema, Pain, Shoulder, Mobility Limitation
Register for Updates
Nasal Obstruction and Olfactory Losses
NCT05920330
Recruiting
About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more in... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/27/2023
Locations: Eye and Ear Institute, 915 Olentangy River Road, ENT, Suite 4000, Columbus, Ohio
Conditions: Nasal Obstruction
Register for Updates
Implant for Walking After Stroke
NCT05740540
Recruiting
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes installing the device and setting the individual up for home use, creating advanced controllers for walking and evaluating the effect of the device over sever... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
06/27/2023
Locations: Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
Conditions: Stroke, Hemiplegia, Gait, Hemiplegic
Register for Updates
A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment
NCT04928677
Recruiting
The purpose of this study to find out whether codrituzumab is a safe treatment that causes few or mild side effects in children and young adults who have solid tumors that express the protein GPC3. The researchers also want to study the way codrituzumab is absorbed, distributed, and cleared from the body.
Gender:
All
Ages:
Between 1 year and 21 years
Trial Updated:
06/27/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Primary Extra-cranial Solid Tumor, Recurrent or Refractory Glypican 3 (GPC3)
Register for Updates
Uncertainty and Firearms: Obtaining Secure Storage
NCT05818696
Recruiting
The goal of this clinical trial is to test whether inclusion of cognitive behavioral therapy (CBT) for Uncertainty-Enhanced (CUE) with Lethal Means Counseling (LMC) is acceptable, feasible, and efficacious in addressing secure firearm storage and associated psychological constructs in active duty servicemembers. The clinical trial aims to: Assess the preliminary efficacy of a LMC intervention, augmented with CUE, on firearm storage practices Examine mechanisms through which CUE and LMC increase... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: Ohio State University Department of Psychiatry and Behavioral Health, Columbus, Ohio
Conditions: Anxiety
Register for Updates