Ohio is currently home to 3227 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
NCT03776162
Recruiting
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL using a blood-enriched implant. BEAR will be compared to bone to patellar tendon to bone autograft (BPTB) reconstruction, a standard ACL surgical reconstruction technique that replaces a torn portion of the ACL with transplanted patellar tendon tissue, and thus requires a... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
05/31/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Anterior Cruciate Ligament Tear
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Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function
NCT06078683
Recruiting
This study is being done to evaluate how a ketone ester (KE) beverage affects heart function and health in people with heart failure compared to a placebo beverage (a beverage made with standard food ingredients that do not contain ketone esters).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/30/2024
Locations: The Ross Heart Hospital, Columbus, Ohio
Conditions: Heart Failure With Preserved Ejection Fraction, Type 2 Diabetes, Metabolic Syndrome
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Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
NCT04197596
Recruiting
BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
Gender:
ALL
Ages:
Between 1 month and 79 years
Trial Updated:
05/30/2024
Locations: Nationwide Children's Hosptial, Columbus, Ohio
Conditions: Viral Infection, Primary Immune Deficiency Disorder
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Registry Study for Radiation Therapy Outcomes
NCT01255748
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: University of Cincinnati Medical Center, Cincinnati, Ohio
Conditions: Neoplasms
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Let's K-Talk - HPV Study for Ethnic Koreans
NCT05884697
Recruiting
The goal of this clinical trial is to test the feasibility, acceptability, and preliminary efficacy of a storytelling video-based intervention using AI chatbot technology (K-Talk) to promote HPV vaccination behavior among Korean Americans aged 18 to 45. The main questions this study aims to answer are: * Is the K-Talk intervention feasible for use among Korean Americans aged 18 to 45? * Is the K-Talk intervention acceptable to the target population? * What is the preliminary efficacy of the K-... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/29/2024
Locations: Minjin Kim, Cincinnati, Ohio
Conditions: Human Papillomavirus Viruses, Papillomavirus Vaccines
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Impact of 60 Days Powdered Tart Cherry Supplementation on Metabolic Syndrome
NCT05614947
Recruiting
Metabolic syndrome (MetSyn) is a growing health concern, with up to 25% of the worlds population having the syndrome. MetSyn is a primary risk factor for cardiovascular disease and type II diabetes development, and is independently associated with all-cause mortality, making it an important disease target. The primary treatment for MetSyn is exercise and weight loss, along with medically necessary treatment. Exercise, along with dietary changes such as increased fiber and polyphenol intake can p... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
05/29/2024
Locations: Ohio University Exercise Physiology Lab, Athens, Ohio
Conditions: Metabolic Syndrome
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NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome
NCT04977388
Recruiting
The purpose of this study is to evaluate whether Northera (Droxidopa) is safe and effective in young adults with Menkes disease who survived the most severe complications of their illness or adults with occipital horn syndrome (OHS), who have trouble with intermittent low blood pressure and other symptoms of dysautonomia. The outcomes and information from this study may help adult survivors of Menkes disease and individuals with OHS lead more normal day-to-day lives.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
05/29/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Menkes Disease, Occipital Horn Syndrome
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Histologic Comparison of Ablative Techniques for Endometriosis
NCT06414083
Recruiting
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy native endometriosis tissue in humans.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Good Samaritan Hospital, Cincinnati, Ohio
Conditions: Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic, Endometriosis; Peritoneum
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IS-001 Injection in Patients Undergoing Robotic-Assisted Gynecological Surgery
NCT05954767
Recruiting
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
05/28/2024
Locations: The Ohio State Unversity, Columbus, Ohio
Conditions: Ureter Injury
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Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: The Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Register for Updates
Solarplast (R) Supplementation Effects Following High-intensity Resistance Exercise
NCT06432868
Recruiting
The primary goal of this investigation is to assess whether Solarplast (R) supplementation will improve recovery following heavy resistance exercise in active adults. The primary questions to be addressed are: Does Solarplast (R) decrease muscle damage and inflammation associated with heavy resistance exercise? Does Solarplast (R) reduce the decline in performance associate with heavy resistance exercise? Researchers will compare Solarplast (R) to a placebo (a look-alike substance that contai... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
05/22/2024
Locations: Kent State University - Exercise Science & Exercise Physiology, Kent, Ohio
Conditions: Muscle Damage
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HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
NCT04904588
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
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