Rhode Island is currently home to 488 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Providence, Warwick, East Providence and Johnston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Early Phase Clinical Trial to Test the Feasibility of an ACT-based Physical Activity Promotion Program for Adults With Depressive Symptoms
NCT05407935
Recruiting
The goal of the proposed project is to conduct a feasibility clinical trial comparing group-based acceptance and commitment therapy for physical activity, (ACT; ACTivity) to a time- and attention-matched standard PA intervention (i.e., PA education, goal-setting, and self-monitoring) plus relaxation training comparison condition (Relaxercise) among 60 low-active adults (ages 18-65) with elevated depressive symptoms. Participants will be randomized to treatment condition, followed for 6 months, i... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/18/2022
Locations: Brown University, Providence, Rhode Island
Conditions: Physical Inactivity
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Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults
NCT05285748
Recruiting
We will randomly assign (blocked on Gender (female, male, other), body mass index (BMI; overweight [25 < BMI < 30]) or obese (30 < BMI <40) and pain status (chronic pain vs not)) adults ages 50-64 into either; (a) self-selected intensity (i.e., SELF-PACED) or (b) prescribed moderate intensity (i.e., PRESCRIBED) conditions. Prior to randomization, persons responding to our ads will participate in the following: (1) telephone screening with the study research assistant (RA) to establish eligibilit... Read More
Gender:
All
Ages:
Between 50 years and 64 years
Trial Updated:
07/18/2022
Locations: Brown University, Providence, Rhode Island
Conditions: Physical Inactivity
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RCT of Pain Perception With Fast and Slow Tenaculum Application
NCT05458037
Recruiting
This project will be a randomized controlled trial (RCT) measuring pain perception with two different tenaculum placement techniques on the uterine cervix. A tenaculum is an instrument used to hold the cervix (the opening to the uterus or womb) in place. The trial will measure pain perception with a Visual Analog Scale (VAS) from 0 to 100 mm for two different tenaculum placement techniques, fast and slow closure on the uterine cervix. The main objective of this study is to determine if there is... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/13/2022
Locations: Women and Infants Hospital, Providence, Rhode Island
Conditions: Pain, Acute, Pain, Procedural
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A Study to Monitor Ambulatory Blood Pressure Monitoring in Hypogonadal Men Treated With Nasal Testosterone Gel
NCT04976595
Recruiting
The purpose of this study is to assess the change in 24-hour ambulatory blood pressure monitoring (ABPM) between baseline (Day 0) and Day 120 following 4 months of testosterone therapy with Natesto.
Gender:
Male
Ages:
Between 18 years and 80 years
Trial Updated:
07/04/2022
Locations: Warren Alpert School of Medicine Brown University, Providence, Rhode Island
Conditions: Hypogonadism
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Safety and Efficacy of the CGuard™ Carotid Stent System in Carotid Artery Stenting
NCT04900844
Recruiting
The objective of this pivotal study is to evaluate the safety and efficacy of the CGuard™ Carotid Stent System in the treatment of carotid artery stenosis in symptomatic and asymptomatic patients undergoing carotid artery stenting (CAS) to a performance goal developed from published CAS literature.
Gender:
All
Ages:
Between 19 years and 80 years
Trial Updated:
06/16/2022
Locations: Miriam Hospital, Providence, Rhode Island
Conditions: Carotid Artery Stenosis
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Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response
NCT02498951
Recruiting
This randomized phase II trial studies how well obinutuzumab works as maintenance treatment in patients with central nervous system lymphoma who have achieved the disappearance of all signs of cancer in response to treatment (complete response) or a decrease in the size of a tumor, or in the extent of cancer in the body, in response to treatment (partial response). Immunotherapy with obinutuzumab, may induce changes in body's immune system and may interfere with the ability of tumor cells to gro... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/09/2022
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Central Nervous System B-Cell Non-Hodgkin Lymphoma
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Biomarkers For Immune Checkpoint Inhibitors
NCT04204434
Recruiting
This is a laboratory, non-treatment study. Immune checkpoint inhibitors are a type of immunotherapy that stimulates a patients immune system to fight their cancer. Immune checkpoint inhibitors are standard, FDA approved treatment for certain types of cancers such as melanoma, lung cancer, kidney cancer and bladder cancer. The laboratories of Dr. Jack Elias and Dr. Chun Geun Lee at Brown University are studying how immune checkpoint inhibitors work.Kintai Therapeutics is a biotech company in Camb... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/19/2022
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Advanced Cancer, Neoplasms
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Trauma Informed Guilt Reduction Therapy
NCT02512445
Recruiting
The goal of this project is to determine if a 6-session psychotherapy intervention will help Veterans feel less deployment-related guilt and less distress related to their guilt. Half of the participants will receive the guilt focused intervention and half will receive a supportive intervention. A supplemental pilot study added in FY2021 will examine the intervention for pandemic-related guilt events.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/04/2022
Locations: VA Providence Medical Center, Providence, Rhode Island
Conditions: Guilt, Shame, Post-traumatic Stress Disorders
Register for Updates
Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections
NCT04552171
Recruiting
The proposed study involves conducting a larger-scale study exploring Game Plan's effects among MSM in the real-world, alongside innovative approaches for expanding HIV testing. Using a hybrid 1 effectiveness-implementation approach, the investigators will recruit up to 360 high-risk, heavy drinking MSM online from several high-incidence areas in the US to participate in a program providing home-based HIV/STI self-tests in the mail at regular intervals over a year (baseline, 6 months, 12 months)... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
03/29/2022
Locations: Brown University School of Public Health, Providence, Rhode Island
Conditions: Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Register for Updates
Improving the Experience of Exercise Among Individuals With Internalized Weight Bias Using Acceptance-based Strategies
NCT05119504
Recruiting
The goal of this study is to test whether an acceptance based intervention can modify the relationship between heart rate and perceived exertion/negative during physical activity among individuals who have a high degree of internalized weight bias.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
11/11/2021
Locations: Weight Control and Diabetes Research Center, Providence, Rhode Island
Conditions: Overweight and Obesity
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Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery
NCT04785885
Recruiting
The efficiency and promptness of heparin anticoagulation is necessary during the structural heart procedures to minimize time from insertion of cannulae to valve deployment in cardiac surgery. The goal of this study is to determine how rapidly the adequacy of heparin induced anticoagulation occurs using two different point of care activated clotting time technologies (iSTAT and Hemochron).
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
09/28/2021
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Transcatheter Aortic Valve Replacement, Cardiac Valve Annuloplasty
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Hand Holding During Light Sedation for Minimally Invasive Spine Surgery Improves Outcomes
NCT05058079
Recruiting
The investigators want to determine whether handholding improves patient satisfaction and reduce patient's anxiety during minimally invasive outpatient spine surgery with monitored anesthesia care.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/16/2021
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Spine, Minimally Invasive
Register for Updates