Rhode Island is currently home to 493 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Providence, Warwick, East Providence and Johnston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes
NCT05723445
Recruiting
This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults with cystic fibrosis-related diabetes (CFRD). We will use continuous glucose monitors (CGM) to assess the LGL diet both in a controlled setting (via a meal delivery company) and in free-living conditions.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/09/2024
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis With Intestinal Manifestations
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Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews
NCT06354465
Recruiting
This qualitative study investigates the potential benefits and challenges of using a once-a-month injectable medication, known as extended-release buprenorphine (XR-B), to treat individuals with opioid use disorder (OUD) within a correctional setting. The research aims to understand if XR-B can be a feasible and effective alternative to the standard daily treatment and to identify which groups within the prison population may benefit the most from this treatment. In-depth interviews are conducte... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/04/2024
Locations: Rhode Island Department of Corrections, Cranston, Rhode Island
Conditions: Opioid Use Disorder, Criminal Justice, Treatment Adherence and Compliance
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Control Systems Engineering for Weight Loss Maintenance
NCT06244888
Recruiting
This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance using behavioral, psychosocial, and environmental indicators evaluated in a system identification experiment. A 6-month behavioral obesity treatment will be administered to produce weight loss. Participants losing at least 3% of initial body weight will be followed for an additional 12 months via daily smartphone surveys that incorporates pas... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/01/2024
Locations: Miriam Hospital Weight Control and Diabetes Resarch Center, Providence, Rhode Island
Conditions: Overweight and Obesity
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Intranasal Insulin for Treatment of Alcohol Use Disorder
NCT05988632
Recruiting
This is a randomized controlled trial (RCT), within-subject, crossover, double-blind, placebo-controlled in non-treatment-seeking individuals with Alcohol Use Disorder (AUD) (N=40, 50% female) randomized to IN insulin or placebo. In a bar laboratory setting, randomized participants will receive a single dose of IN insulin (80IU) or an IN matched placebo (0.9% Saline). Participants will undergo a cue-reactivity paradigm followed by an alcohol challenge that includes an alcohol drink designed to r... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/25/2024
Locations: Brown University, Providence, Rhode Island
Conditions: Alcohol Use Disorder
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Joyuus - A Web-based Tool for Postpartum Care Self-care for Underserved Women
NCT05876559
Recruiting
The goal of this RCT is to evaluate the effectiveness of Joyuus on improving maternal functioning with postpartum moms. The main questions it aims to answer are: * The primary hypothesis is that participants of the Joyuus program will demonstrate improved functional status compared to the control arm participants at 3-month follow-up. * The secondary hypotheses are that participants using the Joyuus tool will demonstrate improvement in depression, anxiety, resilience, social support, and knowle... Read More
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
03/22/2024
Locations: Lisa Marceau, Westerly, Rhode Island
Conditions: Maternal Health
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High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)
NCT05589181
Recruiting
This project, involving two distinct clinical trials, tests whether induction to a higher than currently recommended buprenorphine (BUP) induction dose is safe and can improve the proportion of patients who engage in comprehensive addiction services within 7-day of induction. Trial 1 is a head-to-head comparison of the safety, tolerability and feasibility of high dose BUP induction (32 mg). The study involves two cohorts, (1) a 12mg cohort (standard) to determine baseline data and (2) a 32 mg (... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Rhode Island Hospital Emergency Department, Providence, Rhode Island
Conditions: Opioid Use Disorder
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Metastatic Tumor Research and Outcomes Network
NCT02830451
Recruiting
The registry aims to collect patient information such as patient demographics, co-morbidities, clinical, diagnostic, and therapeutic data, as well as information on adverse events and HRQOL outcomes specific for patients with metastatic spine tumor(s).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: The Warren Alpert Medical School of Brown university Department of Neurosurgery, Providence, Rhode Island
Conditions: Metastatic Spine Tumor
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Primary Tumor Research and Outcomes Network
NCT02790983
Recruiting
This project aims to establish a network of spine oncology centers dedicated to prospective multicenter research of patients diagnosed with a primary tumor of the spine and will include a comprehensive prospective clinical database which will serve as a shared research platform. Demographic, clinical, diagnostic, and therapeutic variables will be used to answer questions about survival and local recurrence, as well as questions about adverse events (AEs), morbidity data, and health-related quali... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/19/2024
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Spinal Column Tumor
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Complex Adult Deformity Surgery (CADS)
NCT04194138
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: University Orthopedics, Providence, Rhode Island
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Reducing Alcohol Use and Sexual Dysfunction in Survivors of Sexual Trauma
NCT05599620
Recruiting
The goal of this clinical trial is to develop and evaluate the preliminary efficacy of an intervention to address alcohol use, sexual distress, and sexual assault risk among college women with a history of sexual victimization. The main questions it aims to answer are: 1) what is the feasibility of the recruitment method, research design, interventionist training methods, and delivery of the intervention; 2) does the intervention, relatively to control, the 2- and 6-month follow-up produces redu... Read More
Gender:
FEMALE
Ages:
Between 18 years and 24 years
Trial Updated:
02/14/2024
Locations: Rhode Island Hospital, Providence, Rhode Island
Conditions: Alcohol Use, Unspecified, Sexual Dysfunction, Sexual Assault
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NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits
NCT05662280
Recruiting
Working memory (WM) deficits are a transdiagnostic feature of adolescent psychopathology that substantially contribute to poor clinical and functional outcomes. This proposal will utilize a multimodal neuroscientific approach to investigate whether non-invasive brain stimulation can modulate the neural mechanisms underlying adolescent WM deficits. Directly in line with NIMH priorities, the researchers will identify the contributing roles of prefrontal and parietal regions in WM processes, as wel... Read More
Gender:
ALL
Ages:
Between 12 years and 18 years
Trial Updated:
01/30/2024
Locations: E. P. Bradley Hospital, East Providence, Rhode Island
Conditions: Working Memory
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Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With Dupilumab
NCT05694884
Recruiting
Multicenter, randomized, double-blind, placebo-controlled, parallel arm clinical study designed to evaluate the efficacy and safety of eblasakimab in participants with moderate-to-severe atopic dermatitis (AD) previously treated with dupilumab.The study consists of a 16-week treatment period and an 8-week follow-up period up to Week 24. Eligible participants will be randomized into one of the 2 treatment arms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: ASLAN Investigative Site, Johnston, Rhode Island
Conditions: Atopic Dermatitis
Register for Updates